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[189581_at] cytochrome P450

Description T10B9.7 /REP_DB=WormBase Gene ID /WP=CE01659 /TR=SW:Q27518 /GB=CAA88607.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=cytochrome P450
Cluster 6grp_high1_10_10 > 74      4grp_highest_8_8 > 03      4grp_high_8_8 > 38      6grp_total > 64      4grp_total > 41      6grp_cgc > 56      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 625
1 2 3 4 range
A 91.7
(-3)
P 		636.9
(3)
P 		492.8
(1.4)
P 		431.5
(0.7)
P 		545
B 123.4
(-3)
P 		716.2
(3)
P 		612.1
(1.9)
P 		475.3
(0.6)
P 		593
C 145.2
(-3)
P 		708.5
(3)
P 		625.5
(2.1)
P 		442.7
(0.2)
P 		563
avr 120.1
(-3) 		687.2
(3) 		576.8
(1.8) 		449.8
(0.5) 		567

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 332
1 2 3 4 5 6 range
A 66.1
(-3)
A 		152.8
(-1.1)
P 		337.4
(3)
P 		187.4
(-0.3)
P 		193.1
(-0.2)
P 		266.2
(1.4)
P 		271
B 52.6
(-3)
P 		148.5
(-1)
P 		341.5
(3)
P 		199.4
(0)
P 		196.1
(-0)
P 		323.8
(2.6)
P 		289
C 58.3
(-3)
P 		176.1
(-0.8)
P 		287.8
(1.2)
P 		212.5
(-0.2)
P 		274.3
(1)
P 		384.7
(3)
P 		326
avr 59
(-3) 		159.1
(-0.7) 		322.2
(2.9) 		199.8
(0.2) 		221.2
(0.7) 		324.9
(3) 		266
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 185
1 2 3 4 range
A 33.4
(-3)
P 		138.3
(3)
P 		128.8
(2.5)
P 		63.2
(-1.3)
P 		105
B 39.3
(-3)
P 		176.9
(3)
P 		141.8
(1.5)
P 		101.3
(-0.3)
P 		138
C 48.1
(-3)
P 		203.7
(2.5)
P 		218
(3)
P 		74.6
(-2.1)
P 		170
avr 40.3
(-3) 		173
(3) 		162.9
(2.5) 		79.7
(-1.2) 		133

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 117
1 2 3 4 5 6 range
A 12.2
(-3)
A 		54.3
(1.1)
P 		73.5
(3)
P 		47.5
(0.5)
P 		58.3
(1.5)
P 		64.8
(2.1)
P 		61
B 18.3
(-3)
P 		49.4
(-1.2)
P 		82.9
(0.8)
P 		52.8
(-1)
P 		79.7
(0.6)
P 		120.7
(3)
P 		102
C 21.6
(-3)
P 		53.7
(-1.2)
P 		73.3
(-0.1)
P 		42.7
(-1.8)
P 		88.8
(0.8)
P 		128.8
(3)
P 		107
avr 17.4
(-3) 		52.5
(-0.6) 		76.6
(1.1) 		47.7
(-0.9) 		75.6
(1) 		104.8
(3) 		87
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189581_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3710
Sequence Type Exemplar sequence
Representative Public ID T10B9.7 NCBI
Target Description T10B9.7 /REP_DB=WormBase Gene ID /WP=CE01659 /TR=SW:Q27518 /GB=CAA88607.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=cytochrome P450
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063708(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063708 NCBI Caenorhabditis elegans CYtochrome P450 family member (cyp-13A2) (cyp-13A2) mRNA, complete cds. 11/11 None
SNAP00000024363 ENSEMBL cdna:SNAP chromosome:CEL140:II:9783729:9787264:-1 11/11 None
GENEFINDER00000024379 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9779256:9787264:-1 10/11 None
T10B9.7 ENSEMBL cdna:known chromosome:CEL140:II:9783729:9787264:-1 gene:T10B9.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9783725-9787261(-) 100.0 100.0
Public Domain and Genome References
Gene Title cytochrome P450
Gene Symbol cyp-13A2
Ensembl T10B9.7
Entrez Gene 188360 Entrez gene
SwissProt Q27518 EMBL-EBI
WormBase CE01659 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.6939.1.S1_S_AT similar to Thromboxane-A synthase (TXA synthase) (TXS) cfa
CHICKEN:GGAAFFX.8112.1.S1_AT similar to thromboxane synthase gga
CHICKEN:GGAAFFX.8112.2.S1_AT similar to thromboxane synthase gga
CHICKEN:GGAAFFX.8112.3.S1_S_AT similar to thromboxane synthase gga
HG-U133_PLUS_2:208130_S_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U133A:208130_S_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
PLASMODIUM_ANOPHELES:208130_S_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-FOCUS:208130_S_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U133A_2:208130_S_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HU35KSUBD:RC_R76437_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HUGENEFL:M80647_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
U133_X3P:G13699839_3P_S_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U95AV2:33777_AT thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
U133_X3P:HS2.375661.1.S1_3P_X_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
U133_X3P:1566501_3P_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U133_PLUS_2:1566501_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U133B:236345_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U133_PLUS_2:236345_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HG-U95B:58066_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
HU35KSUBC:RC_AA044825_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
U133_X3P:HS.103446.0.A1_3P_AT Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) hs
MOE430A:1416827_AT thromboxane A synthase 1, platelet mm
MOUSE430A_2:1416827_AT thromboxane A synthase 1, platelet mm
MOUSE430_2:1416827_AT thromboxane A synthase 1, platelet mm
MU11KSUBA:L18868_S_AT thromboxane A synthase 1, platelet mm
MG-U74AV2:92387_AT thromboxane A synthase 1, platelet mm
MG-U74AV2:162136_R_AT Thromboxane A synthase 1, platelet, mRNA (cDNA clone MGC:32210 IMAGE:5007629) mm
RG-U34A:D28773_S_AT thromboxane A synthase 1 rn
RAE230A:1368027_AT thromboxane A synthase 1 rn
RAT230_2:1368027_AT thromboxane A synthase 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88607 Hypothetical protein T10B9.7 [Caenorhabditis elegans] ref|NP_496109.1| CYtochrome P450 family member (cyp-13A2) [Caenorhabditis elegans] sp|Q27518|C13A2_CAEEL Putative cytochrome P450 CYP13A2 0.0
blast CAE57972 Hypothetical protein CBG01033 [Caenorhabditis briggsae] 0.0
blast CAA88610 Hypothetical protein T10B9.8 [Caenorhabditis elegans] ref|NP_496108.1| CYtochrome P450 family member (cyp-13A1) [Caenorhabditis elegans] sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 0.0
blast CAE57997 Hypothetical protein CBG01060 [Caenorhabditis briggsae] 1.0E-175
Protein Families
Method ID Description E-Value
p450 CP13_ONCMY Animalia; CYP1A3; tro; CP13_ONCMY; Trout; Q92109 1.0E-125
p450 CP13_ONCMY Animalia; CYP1A3; tro; CP13_ONCMY; Trout; Q92109 1.0E-132
Protein Domains
Database ID Description E-Value
Pfam IPR001128 EMBL-EBI Cytochrome P450 3.9E-81
Pfam IPR001128 EMBL-EBI Cytochrome P450 9.8E-81
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.5E-21
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.3E-66
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496109.1 1 5-27
T10B9.7 1 5-27
SNAP00000024363 1 5-27
GENEFINDER00000024379 1 5-27
Sequence
Target Sequence 
>C. ELEGANS:189581_AT
atacaactgcattatcactatcatatgttacttacctattagctgttaatccaaaaattc
aagaaaaagtaattgaagaaattgctcgtgaattcggaacttcagaagtagaatttgaga
agcttgggaggctgaaatatatggattgtgtgatcaaggaagctctccgtctgtatccat
tagcttctatttcaaattcccgaaagtgtatgaaaacaacaactgtgaatggtgtaaaga
ttgaagctggtgtatacgttcaaatggacacttggtctcttcattatgatccagaattat
ggggagaagatgtcaaagaattcaagccagaacgatggtccaccgacgagccattagagc
acaaaggagcatatcttccatttggacttggaccacgtcagtgtattggaatgaggctgg
ctattatggagcagaagattctactgactcatttattaaaaaattatacatttgagacag
gaaataagactagaattcctttgaaactggtgggaagtgctactacatcgcctgaagat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATACAACTGCATTATCACTATCATA 220 25 989 Antisense
ATATGTTACTTACCTATTAGCTGTT 450 19 1011 Antisense
TCAAGGAAGCTCTCCGTCTGTATCC 491 631 1142 Antisense
GTCTGTATCCATTAGCTTCTATTTC 679 471 1157 Antisense
GTTCAAATGGACACTTGGTCTCTTC 14 445 1246 Antisense
CTTGGTCTCTTCATTATGATCCAGA 163 219 1259 Antisense
TCAAGCCAGAACGATGGTCCACCGA 588 629 1310 Antisense
TCCACCGACGAGCCATTAGAGCACA 598 589 1327 Antisense
AGGAGCATATCTTCCATTTGGACTT 694 55 1353 Antisense
GGACTTGGACCACGTCAGTGTATTG 150 525 1372 Antisense
AAGTGCTACTACATCGCCTGAAGAT 344 155 1503 Antisense
Sequence Source Affymetrix Proprietary Database