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[189580_at] cysteine protease

Description M04G12.2 /REP_DB=WormBase Gene ID /WP=CE12424 /TR=P92005 /GB=CAB03209.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=cysteine protease
Cluster 6grp_highest_10_10 > 02      6grp_high1_10_10 > 10      4grp_highest_8_8 > 44      4grp_high_8_8 > 08      6grp_highest_nonorm > 36      6grp_total > 50      4grp_total > 23      6grp_cgc > 60      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2128
1 2 3 4 range
A 6046.6
(3)
P 		4079
(-3)
P 		4969.9
(-0.3)
P 		5218.9
(0.5)
P 		1968
B 6207
(3)
P 		4263.7
(-2.8)
P 		4208.5
(-3)
P 		6032.8
(2.5)
P 		1999
C 5924.4
(3)
P 		4632.3
(-3)
P 		5127.6
(-0.7)
P 		5294.4
(0.1)
P 		1292
avr 6059.3
(3) 		4325
(-3) 		4768.7
(-1.5) 		5515.4
(1.1) 		1734

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3089
1 2 3 4 5 6 range
A 4135.4
(-0.3)
P 		4936.7
(1.3)
P 		4534.1
(0.5)
P 		5771.6
(3)
P 		2780.1
(-3)
P 		3046.4
(-2.5)
P 		2992
B 4297.1
(3)
P 		3840.6
(1.3)
P 		3312.4
(-0.7)
P 		3649.5
(0.6)
P 		3176.1
(-1.2)
P 		2682.4
(-3)
P 		1615
C 5257.8
(2.6)
P 		3540.2
(-1.6)
P 		5420.6
(3)
P 		4608.8
(1)
P 		3578.1
(-1.5)
P 		2989.3
(-3)
P 		2431
avr 4563.4
(2.6) 		4105.8
(1.1) 		4422.4
(2.1) 		4676.6
(3) 		3178.1
(-2.1) 		2906
(-3) 		1771
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1438
1 2 3 4 range
A 2201.6
(3)
P 		885.4
(-2.5)
P 		1299.2
(-0.8)
P 		763.9
(-3)
P 		1438
B 1979.4
(3)
P 		1053
(-2.5)
P 		975.2
(-3)
P 		1285.6
(-1.1)
P 		1004
C 1961.1
(3)
P 		1331.8
(-0.5)
P 		1787.1
(2)
P 		892.7
(-3)
P 		1068
avr 2047.4
(3) 		1090.1
(-2.4) 		1353.8
(-0.9) 		980.7
(-3) 		1067

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1207
1 2 3 4 5 6 range
A 762.3
(-2.9)
P 		1755.7
(3)
P 		987.4
(-1.5)
P 		1463.8
(1.3)
P 		838.9
(-2.4)
P 		741.7
(-3)
P 		1014
B 1495.2
(3)
P 		1278.4
(1.1)
P 		804.3
(-3)
P 		966.6
(-1.6)
P 		1290.4
(1.2)
P 		1000.2
(-1.3)
P 		691
C 1948.8
(3)
P 		1080.2
(-2.1)
P 		1379.6
(-0.3)
P 		926.8
(-3)
P 		1157.8
(-1.6)
P 		1000.7
(-2.6)
P 		1022
avr 1402.1
(3) 		1371.4
(2.6) 		1057.1
(-1.2) 		1119.1
(-0.5) 		1095.7
(-0.8) 		914.2
(-3) 		488
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189580_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13867
Sequence Type Exemplar sequence
Representative Public ID M04G12.2 NCBI
Target Description M04G12.2 /REP_DB=WormBase Gene ID /WP=CE12424 /TR=P92005 /GB=CAB03209.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=cysteine protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073917(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073917 NCBI Caenorhabditis elegans CathePsin Z family member (cpz-2) (cpz-2) mRNA, complete cds. 11/11 None
SNAP00000041635 ENSEMBL cdna:SNAP chromosome:CEL140:V:13383856:13385584:1 11/11 None
GENEFINDER00000041638 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:13383856:13385584:1 11/11 None
M04G12.2 ENSEMBL cdna:known chromosome:CEL140:V:13383781:13385653:1 gene:M04G12.2 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:13383855-13385584(+) 100.0 100.0
Public Domain and Genome References
Gene Title cysteine protease
Gene Symbol cpz-2
Ensembl M04G12.2
Entrez Gene 179818 Entrez gene
SwissProt P92005 EMBL-EBI
WormBase CE12424 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03209 Hypothetical protein M04G12.2 [Caenorhabditis elegans] ref|NP_506318.1| CathePsin Z family member (cpz-2) [Caenorhabditis elegans] 0.0
blast CAE62609 Hypothetical protein CBG06727 [Caenorhabditis briggsae] 0.0
blast tpg|DAA01510.1 TPA: cathepsin Z-like enzyme; CPZ-1 [Caenorhabditis elegans] gb|AAB54210.2| Cathepsin z protein 1 [Caenorhabditis elegans] ref|NP_491023.2| CathePsin Z family member (cpz-1) [Caenorhabditis elegans] 9.0E-91
Protein Domains
Database ID Description E-Value
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 2.8E-61
Sequence
Target Sequence 
>C. ELEGANS:189580_AT
aacgatcgtttcaacgttgctcgcaagggaagatggccaatgactcaattgtcgccacag
gaaattattgactgcaatggaaagggaaattgtcaaggtggagaaatcggaaatgtgcta
gagcacgctaagatccaaggacttgtggaggaaggatgcaatgtctacagagccacaaat
ggagaatgtaacccataccatcgctgtggatcttgctggccaaacgagtgcttctccctt
accaactacactcgttattacgttaaggattacggacaggtccagggacgtgacaaaatc
atgtctgaaatcaagaaaggaggaccaattgcatgtgccattggagcaacaaagaaattc
gagtatgaatatgtgaaaggagtctactcagagaagagtgatctcgaatccaatcatatc
atttcactcactggatggggagttgatgagaacggagttgagtactggatcgccagaaac
agttggggagaagcttggggagagctcggatggttccgtgtggtcacttcaaagtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACGATCGTTTCAACGTTGCTCGCA 672 143 793 Antisense
GGCCAATGACTCAATTGTCGCCACA 449 543 827 Antisense
TAGAGCACGCTAAGATCCAAGGACT 140 653 911 Antisense
GGATGCAATGTCTACAGAGCCACAA 640 513 946 Antisense
AACCCATACCATCGCTGTGGATCTT 643 145 982 Antisense
GATCTTGCTGGCCAAACGAGTGCTT 464 419 1001 Antisense
TACCAACTACACTCGTTATTACGTT 617 623 1032 Antisense
AGGAGGACCAATTGCATGTGCCATT 584 55 1110 Antisense
CAATCATATCATTTCACTCACTGGA 394 179 1203 Antisense
GGGGAGAGCTCGGATGGTTCCGTGT 613 497 1289 Antisense
GGTTCCGTGTGGTCACTTCAAAGTT 489 505 1304 Antisense
Sequence Source Affymetrix Proprietary Database