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[189579_at]

Description C37A2.4 /REP_DB=WormBase Gene ID /WP=CE24832 /GEN=cye-1 /TR=O01501 /GB=AAK68235.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=cyclin
Cluster 6grp_total > 67      4grp_total > 09      6grp_cgc > 48      6grp_cgc_sub > Da      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 111
1 2 3 4 range
A 3.7
(-3)
A 		14.2
(3)
A 		4
(-2.8)
A 		13.2
(2.4)
A 		11
B 18.4
(3)
A 		11
(-0.3)
A 		5.1
(-3)
A 		14.7
(1.3)
A 		13
C 5.3
(-3)
A 		7.4
(-2.9)
A 		29.1
(-1.7)
A 		114.9
(3)
A 		110
avr 9.1
(-3) 		10.9
(-2.7) 		12.7
(-2.4) 		47.6
(3) 		39

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 83
1 2 3 4 5 6 range
A 5.3
(-3)
A 		15.1
(-1.9)
A 		11
(-2.3)
A 		7.5
(-2.7)
A 		7.8
(-2.7)
A 		57.7
(3)
A 		52
B 12.1
(-1.8)
A 		5.2
(-2.8)
A 		6.4
(-2.6)
A 		3.5
(-3)
A 		24.1
(-0.1)
A 		45.9
(3)
A 		42
C 10.9
(-2.4)
A 		46.4
(0.1)
A 		3.2
(-3)
A 		8.2
(-2.6)
A 		5.1
(-2.9)
A 		86.5
(3)
A 		83
avr 9.4
(-2.7) 		22.2
(-1.3) 		6.9
(-2.9) 		6.4
(-3) 		12.3
(-2.4) 		63.4
(3) 		57
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 18
1 2 3 4 range
A 1.3
(-2.1)
A 		3.1
(3)
A 		1
(-3)
A 		1.9
(-0.4)
A 		2
B 5.9
(3)
A 		2.7
(-1.1)
A 		1.2
(-3)
A 		3.1
(-0.6)
A 		5
C 1.8
(-3)
A 		2.1
(-2.9)
A 		10.1
(-0.2)
A 		19.4
(3)
A 		18
avr 3
(-2.6) 		2.6
(-3) 		4.1
(-1.4) 		8.1
(3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 28
1 2 3 4 5 6 range
A 1
(-3)
A 		5.4
(-1)
A 		2.4
(-2.4)
A 		1.9
(-2.6)
A 		2.4
(-2.4)
A 		14
(3)
A 		13
B 4.2
(-1.8)
A 		1.7
(-2.7)
A 		1.6
(-2.7)
A 		0.9
(-3)
A 		9.8
(0.3)
A 		17.1
(3)
A 		16
C 4.1
(-2.3)
A 		14.2
(-0.1)
A 		0.8
(-3)
A 		1.7
(-2.8)
A 		1.7
(-2.8)
A 		29
(3)
A 		28
avr 3.1
(-2.5) 		7.1
(-1.2) 		1.6
(-3) 		1.5
(-3) 		4.6
(-2) 		20
(3) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189579_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1001
Sequence Type Exemplar sequence
Representative Public ID C37A2.4 NCBI
Target Description C37A2.4 /REP_DB=WormBase Gene ID /WP=CE24832 /GEN=cye-1 /TR=O01501 /GB=AAK68235.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=cyclin
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001025856(11), NM_001025857(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001025856 NCBI Caenorhabditis elegans CYclin E family member (cye-1) (cye-1) mRNA, complete cds. 11/11 None
NM_001025857 NCBI Caenorhabditis elegans CYclin E family member (cye-1) (cye-1) mRNA, complete cds. 11/11 None
SNAP00000014176 ENSEMBL cdna:SNAP chromosome:CEL140:I:6788955:6792014:1 11/11 None
GENEFINDER00000014190 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6788955:6795204:1 11/11 None
C37A2.4a ENSEMBL cdna:known chromosome:CEL140:I:6788940:6792032:1 gene:C37A2.4 11/11 None
C37A2.4b ENSEMBL cdna:known chromosome:CEL140:I:6788955:6792493:1 gene:C37A2.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6788883-6791943(+) 100.0 100.0
Public Domain and Genome References
Ensembl C37A2.4
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAK68235 Cyclin e protein 1, isoform a [Caenorhabditis elegans] ref|NP_001021027.1| CYclin E family member (cye-1) [Caenorhabditis elegans] gb|AAM78547.1| cyclin E [Caenorhabditis elegans] sp|O01501|CCNE_CAEEL G1/S-specific cyclin E gb|AAC63505.1| cyclin E [Caenorhabditis elegans] 0.0
blast AAP13781 Cyclin e protein 1, isoform b [Caenorhabditis elegans] ref|NP_001021028.1| CYclin E family member (cye-1) [Caenorhabditis elegans] 0.0
blast T30156 hypothetical protein C37A2.4 - Caenorhabditis elegans 0.0
blast AAB52448 Hypothetical protein C37A2.3 [Caenorhabditis elegans] ref|NP_491942.1| C37A2.3 [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec ACDL_HUMAN (P28330) Acyl-CoA dehydrogenase, long-chain specific, mitochondrial precursor (EC 1.3.99.13) (LCAD) 1.0E-131
Protein Domains
Database ID Description E-Value
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 4.9E-49
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 4.9E-49
Pfam IPR006090 EMBL-EBI Acyl-CoA dehydrogenase, C-terminal 7.0E-55
Pfam IPR006091 EMBL-EBI Acyl-CoA dehydrogenase, central domain 4.3E-58
Pfam IPR006092 EMBL-EBI Acyl-CoA dehydrogenase, N-terminal 1.4E-9
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 8.9E-13
Sequence
Target Sequence 
>C. ELEGANS:189579_AT
atcgattttgctcatctcaccgatagtgcattcacctgtgataatattcgaactatggaa
gttcttatcgtcaagtatattgggtggagtcttgggccaatcacaagtattcaatggctc
tcaacatatcttcaattactcggaaccggcaaaaagaacaagtctgatcactacgaagag
caaaacatgtacgtgccagaattactccgttcagaatatcttgaaatgtgtaaaattctc
gattttctgctatttgagatcgactcatttactttctcctatcgtaccatcgctgctgct
gttctttttgtcaactatgagccaacttgtgctgttgagaaggctaccggatttatgcag
gctcaacttgaaaaagttattgaatatgttgaaccggtgtgccgggcgttcgccaaacaa
cgacaact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCGATTTTGCTCATCTCACCGATA 55 37 997 Antisense
CTCACCGATAGTGCATTCACCTGTG 208 227 1012 Antisense
GGGTGGAGTCTTGGGCCAATCACAA 610 495 1078 Antisense
GGCTCTCAACATATCTTCAATTACT 570 539 1112 Antisense
GTACGTGCCAGAATTACTCCGTTCA 346 459 1185 Antisense
TCGACTCATTTACTTTCTCCTATCG 535 601 1256 Antisense
CTGCTGCTGTTCTTTTTGTCAACTA 493 237 1289 Antisense
TGTGCTGTTGAGAAGGCTACCGGAT 198 557 1324 Antisense
GCTACCGGATTTATGCAGGCTCAAC 313 301 1339 Antisense
TGTTGAACCGGTGTGCCGGGCGTTC 151 561 1383 Antisense
GGGCGTTCGCCAAACAACGACAACT 591 491 1400 Antisense
Sequence Source Affymetrix Proprietary Database