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[189575_at] cytochrome P450

Description T10B9.3 /REP_DB=WormBase Gene ID /WP=CE01657 /TR=SW:Q27515 /GB=CAA88605.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=cytochrome P450
Cluster 6grp_total > 19      4grp_total > 34      6grp_cgc > 0      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 51
1 2 3 4 range
A 37.4
(-3)
A 		79.6
(3)
A 		48.3
(-1.5)
A 		58
(-0.1)
A 		42
B 28.3
(-3)
A 		57.5
(3)
A 		48.4
(1.1)
A 		55.9
(2.7)
A 		29
C 59.5
(0.9)
A 		60.1
(1)
A 		41.7
(-3)
A 		69.3
(3)
A 		28
avr 41.7
(-3) 		65.7
(3) 		46.1
(-1.9) 		61.1
(1.9) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 120
1 2 3 4 5 6 range
A 88.8
(-1.3)
P 		74.3
(-3)
A 		106
(0.6)
P 		126.8
(3)
P 		104.9
(0.5)
P 		79
(-2.5)
A 		53
B 105.1
(3)
M 		26.7
(-1.8)
A 		6.5
(-3)
A 		84.9
(1.8)
A 		96.7
(2.5)
A 		87.3
(1.9)
P 		99
C 106.2
(3)
M 		47.1
(-3)
A 		82.8
(0.6)
A 		88.5
(1.2)
A 		89.4
(1.3)
P 		90.4
(1.4)
P 		59
avr 100
(3) 		49.4
(-3) 		65.1
(-1.1) 		100.1
(3) 		97
(2.6) 		85.6
(1.3) 		51
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 13.6
(0.5)
A 		17.3
(3)
A 		12.6
(-0.2)
A 		8.5
(-3)
A 		9
B 9
(-3)
A 		14.2
(3)
A 		11.2
(-0.5)
A 		11.9
(0.3)
A 		5
C 19.7
(3)
A 		17.3
(1.2)
A 		14.5
(-0.9)
A 		11.7
(-3)
A 		8
avr 14.1
(0.6) 		16.3
(3) 		12.8
(-0.7) 		10.7
(-3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 16.4
(-3)
P 		26.4
(0.8)
A 		23.1
(-0.5)
P 		32.2
(3)
P 		31.7
(2.8)
P 		19.2
(-1.9)
A 		16
B 36.6
(2.6)
M 		8.9
(-1.8)
A 		1.6
(-3)
A 		22.5
(0.3)
A 		39.3
(3)
A 		32.5
(1.9)
P 		38
C 39.4
(3)
M 		14.4
(-3)
A 		21.1
(-1.4)
A 		17.8
(-2.2)
A 		28.9
(0.5)
P 		30.3
(0.8)
P 		25
avr 30.8
(2.2) 		16.6
(-2.6) 		15.3
(-3) 		24.2
(-0) 		33.3
(3) 		27.3
(1) 		18
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189575_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2818
Sequence Type Exemplar sequence
Representative Public ID T10B9.3 NCBI
Target Description T10B9.3 /REP_DB=WormBase Gene ID /WP=CE01657 /TR=SW:Q27515 /GB=CAA88605.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=cytochrome P450
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063712(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063712 NCBI Caenorhabditis elegans CYtochrome P450 family member (cyp-13A6) (cyp-13A6) mRNA, complete cds. 11/11 None
SNAP00000024369 ENSEMBL cdna:SNAP chromosome:CEL140:II:9800771:9802632:-1 11/11 None
GENEFINDER00000024375 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9800771:9802632:-1 11/11 None
T10B9.3 ENSEMBL cdna:known chromosome:CEL140:II:9800672:9802632:-1 gene:T10B9.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9800767-9802629(-) 100.0 100.0
Public Domain and Genome References
Gene Title cytochrome P450
Gene Symbol cyp-13A6
Ensembl T10B9.3
Entrez Gene 188357 Entrez gene
SwissProt Q27515 EMBL-EBI
WormBase CE01657 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:19261_AT cytochrome P450 family protein at
ATH1-121501:266736_AT cytochrome P450 family protein at
CANINE:1591395_AT cytochrome P450 3A26 cfa
CANINE:1582392_S_AT cytochrome P450 3A26 cfa
CANINE_2:CFA.59.1.S1_S_AT cytochrome P450 3A26 cfa
CANINE_2:CFAAFFX.23044.1.S1_AT cytochrome P450 3A26 cfa
DROSOPHILA_2:1641428_AT Cytochrome P450-9c1 dm
DROSGENOME1:141780_AT Cytochrome P450-9c1 dm
HG-U133_PLUS_2:205765_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133A:205765_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-FOCUS:205765_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133A_2:205765_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HU35KSUBA:X90579_S_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HU35KSUBA:J04813_S_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HU35KSUBD:RC_N54855_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HUGENEFL:D00408_S_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133_PLUS_2:214234_S_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133A_2:214234_S_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133A:214234_S_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
U133_X3P:G4503230_3P_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
U133_X3P:HS.269340.0.S1_3P_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
U133_X3P:HS.166079.0.S1_3P_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133A_2:214235_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133_PLUS_2:214235_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133A:214235_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133_PLUS_2:243015_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133B:243015_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U95AV2:37124_I_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U95AV2:37125_F_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U95AV2:38229_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U95C:62681_AT cytochrome P450, family 3, subfamily A, polypeptide 5 hs
HG-U133_PLUS_2:238942_AT Cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 hs
HG-U133B:238942_AT Cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 hs
HG-U95C:53992_AT Cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 hs
HG-U95D:86397_AT Cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 hs
U133_X3P:HS.150276.0.A1_3P_AT Cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 hs
MU11KSUBB:X60452_F_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MU11KSUBB:MSA.2228.0_F_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MG-U74AV2:93770_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MG-U74AV2:101638_S_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MOE430A:1416809_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MOUSE430A_2:1416809_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MOUSE430_2:1416809_AT cytochrome P450, family 3, subfamily a, polypeptide 11 mm
MOUSE430_2:1419704_AT cytochrome P450, family 3, subfamily a, polypeptide 41 mm
MOE430A:1419704_AT cytochrome P450, family 3, subfamily a, polypeptide 41 mm
MOUSE430A_2:1419704_AT cytochrome P450, family 3, subfamily a, polypeptide 41 mm
MU11KSUBA:AA238348_F_AT cytochrome P450, family 3, subfamily a, polypeptide 41 mm
MOE430A:1426064_AT cytochrome P450, family 3, subfamily a, polypeptide 44 mm
MOUSE430A_2:1426064_AT cytochrome P450, family 3, subfamily a, polypeptide 44 mm
MOUSE430_2:1426064_AT cytochrome P450, family 3, subfamily a, polypeptide 44 mm
MU19KSUBA:TC22123_F_AT Cyp3a41 mRNA for cytochrome P450 mm
MU19KSUBB:TC33794_F_AT Cytochrome P450, family 3, subfamily a, polypeptide 11, mRNA (cDNA clone MGC:18636 IMAGE:4194909) mm
MU19KSUBC:TC40932_F_AT Cytochrome P450, family 3, subfamily a, polypeptide 11, mRNA (cDNA clone MGC:18636 IMAGE:4194909) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88605 Hypothetical protein T10B9.3 [Caenorhabditis elegans] ref|NP_496113.1| CYtochrome P450 family member (cyp-13A6) [Caenorhabditis elegans] sp|Q27515|C13A6_CAEEL Putative cytochrome P450 CYP13A6 0.0
blast CAE57966 Hypothetical protein CBG01027 [Caenorhabditis briggsae] 0.0
blast CAA88604 Hypothetical protein T10B9.2 [Caenorhabditis elegans] ref|NP_496112.1| CYtochrome P450 family member (cyp-13A5) [Caenorhabditis elegans] sp|Q27514|C13A5_CAEEL Putative cytochrome P450 CYP13A5 1.0E-167
Protein Families
Method ID Description E-Value
p450 CP14_CHICK Animalia; CYP1A4; chi; CP14_CHICK; Gallus gallus; P79760 1.0E-125
p450 CP14_CHICK Animalia; CYP1A4; chi; CP14_CHICK; Gallus gallus; P79760 1.0E-126
Protein Domains
Database ID Description E-Value
Pfam IPR001128 EMBL-EBI Cytochrome P450 5.4E-85
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.3E-60
Pfam IPR001128 EMBL-EBI Cytochrome P450 7.0E-18
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496113.1 1 2-24
T10B9.3 1 2-24
SNAP00000024369 1 2-24
GENEFINDER00000024375 1 2-24
Sequence
Target Sequence 
>C. ELEGANS:189575_AT
gtgtttcgtatttttagctgctggctttgacacaactgcattatctctctcatatgctac
atatcttcttgcaacacatccagaaatccaaacaaaattacaagaagaagtggacagaga
gtgtccagatcccgaaatcttctttgatcatttatcgaaactgaaatatttggagtgtgt
aatgaaagaaacgttgagattatatccattaggaacgacagcaaacacgagaaaatgtat
gcgagagacaacaatcaacggggtgaattttgatgagggaatgaacattcaagttgacac
atggacactacatcacaatccaagaatttggggagaagacgtagaagacttcaaacccga
aaggtgggaaaacggagcttgtgagcatttggagcacaatggatcgtacattccatttgg
ctcgggaccacgtcagtgcattggaatgagactagctcaaatggagcagaagattttatt
ggctcagattctcaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGTTTCGTATTTTTAGCTGCTGGC 698 485 963 Antisense
TTTTAGCTGCTGGCTTTGACACAAC 580 673 974 Antisense
TTGACACAACTGCATTATCTCTCTC 282 705 989 Antisense
ATTATCTCTCTCATATGCTACATAT 598 13 1002 Antisense
GCTACATATCTTCTTGCAACACATC 192 303 1018 Antisense
GCAACACATCCAGAAATCCAAACAA 461 319 1033 Antisense
CAGAGAGTGTCCAGATCCCGAAATC 11 207 1077 Antisense
ATCCCGAAATCTTCTTTGATCATTT 179 39 1091 Antisense
GACACATGGACACTACATCACAATC 288 367 1258 Antisense
CGGAGCTTGTGAGCATTTGGAGCAC 413 243 1335 Antisense
GATTTTATTGGCTCAGATTCTCAAA 383 429 1434 Antisense
Sequence Source Affymetrix Proprietary Database