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[189565_at] C2 domain protein

Description T23H2.2 /REP_DB=WormBase Gene ID /WP=CE14108 /TR=P91493 /GB=AAC48201.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=C2 domain protein
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 16      4grp_highest_8_8 > 61      4grp_high_8_8 > 18      6grp_highest_nonorm > 13      6grp_total > 14      4grp_total > 30      6grp_highest_sub > De      6grp_cgc > 30      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3901
1 2 3 4 range
A 5389.8
(3)
P 		2935.2
(-1)
P 		1700.1
(-3)
P 		4702.4
(1.9)
P 		3690
B 5600.8
(3)
P 		2735.3
(-1.6)
P 		1841.6
(-3)
P 		4449
(1.2)
P 		3759
C 4878.6
(3)
P 		2320.8
(-2)
P 		1805.5
(-3)
P 		4134.7
(1.5)
P 		3073
avr 5289.7
(3) 		2663.8
(-1.5) 		1782.4
(-3) 		4428.7
(1.5) 		3507

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2264
1 2 3 4 5 6 range
A 3630.9
(2.7)
P 		3712.4
(3)
P 		2052
(-2.9)
P 		2724.8
(-0.5)
P 		2035.7
(-3)
P 		2542.4
(-1.2)
P 		1677
B 3220
(3)
P 		3182
(2.8)
P 		2564.8
(0.2)
P 		2589.4
(0.3)
P 		1808.5
(-3)
P 		1960.5
(-2.4)
P 		1412
C 4072.7
(3)
P 		3028.5
(0.1)
P 		3259.6
(0.7)
P 		2846.5
(-0.4)
P 		2455.2
(-1.5)
P 		1910.4
(-3)
P 		2162
avr 3641.2
(3) 		3307.6
(1.7) 		2625.5
(-1) 		2720.2
(-0.6) 		2099.8
(-3) 		2137.8
(-2.9) 		1541
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1536
1 2 3 4 range
A 1962.4
(3)
P 		637.2
(-2.2)
P 		444.4
(-3)
P 		688.3
(-2)
P 		1518
B 1786
(3)
P 		675.6
(-1.9)
P 		426.7
(-3)
P 		948.1
(-0.7)
P 		1359
C 1615
(3)
P 		667.2
(-2.8)
P 		629.3
(-3)
P 		697.2
(-2.6)
P 		986
avr 1787.8
(3) 		660
(-2.3) 		500.1
(-3) 		777.9
(-1.7) 		1288

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1063
1 2 3 4 5 6 range
A 669.3
(-1.5)
P 		1320.3
(3)
P 		446.9
(-3)
P 		691.1
(-1.3)
P 		614.3
(-1.9)
P 		619
(-1.8)
P 		873
B 1120.4
(3)
P 		1059.2
(2.3)
P 		622.8
(-3)
P 		685.8
(-2.2)
P 		734.8
(-1.6)
P 		731.1
(-1.7)
P 		498
C 1509.6
(3)
P 		924.1
(-0.7)
P 		829.6
(-1.4)
P 		572.4
(-3)
P 		794.5
(-1.6)
P 		639.5
(-2.6)
P 		937
avr 1099.8
(3) 		1101.2
(3) 		633.1
(-3) 		649.8
(-2.8) 		714.5
(-2) 		663.2
(-2.6) 		468
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189565_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2226
Sequence Type Exemplar sequence
Representative Public ID T23H2.2 NCBI
Target Description T23H2.2 /REP_DB=WormBase Gene ID /WP=CE14108 /TR=P91493 /GB=AAC48201.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=C2 domain protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059452(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059452 NCBI Caenorhabditis elegans SyNapTotagmin family member (snt-4) (snt-4) mRNA, complete cds. 11/11 A 
SNAP00000032983 ENSEMBL cdna:SNAP chromosome:CEL140:I:6444207:6449032:1 11/11 None
GENEFINDER00000032992 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6444286:6449032:1 11/11 None
T23H2.2 ENSEMBL cdna:known chromosome:CEL140:I:6444286:6449032:1 gene:T23H2.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6445816-6448961(+) 100.0 100.0
Public Domain and Genome References
Gene Title C2 domain protein
Gene Symbol snt-4
Ensembl T23H2.2
Entrez Gene 172346 Entrez gene
SwissProt P91493 EMBL-EBI
WormBase CE30456 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM15607 Synaptotagmin protein 4 [Caenorhabditis elegans] ref|NP_491853.2| SyNapTotagmin family member (snt-4) [Caenorhabditis elegans] 0.0
blast CAE67192 Hypothetical protein CBG12628 [Caenorhabditis briggsae] 0.0
blast T28967 hypothetical protein T23H2.2 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000008 EMBL-EBI C2 domain 3.2E-24
Pfam IPR000008 EMBL-EBI C2 domain 5.8E-30
Pfam IPR000008 EMBL-EBI C2 domain 3.2E-24
Pfam IPR000008 EMBL-EBI C2 domain 5.8E-30
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_491853.2 1 15-37
T23H2.2 1 15-37
SNAP00000032983 1 36-58
GENEFINDER00000032992 1 15-37
Sequence
Target Sequence 
>C. ELEGANS:189565_AT
accaccagcccagtttatgaggagcaatttgcaatgtatggagtcactcacgagcaagtt
aactttgccacgttgcacttccaggtcgtcgcattcgatcgttactcccgagacactgtc
gttggagaatgtgtctacagattggctgatgcagaacttcaagttcacaatgagatgaga
gttgaactccctctcctcccacgtgccactgatactgtagctgctcgtggagagcttctt
ctctcattgacatatcaagctgcattcaacaatttgacagttgttgttctcaaagcccgt
ggactcggaggacgaaacgatgccggaactgcagatccatttgtcaagttatacttgcgc
aaggaaagtggagaacgtatcgttaaaaagagaacacatgtgagaaggtctactttgaat
cctgtctacaacgaatcgtttgtctttgaacttccagatgatagattggaacattctgtt
attgacttgcaggtgatcaatcatgaccgtgttaaccgtaatgatgtaattggccgtgcc
cttcttaatat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACCACCAGCCCAGTTTATGAGGAGC 709 85 562 Antisense
AGTTAACTTTGCCACGTTGCACTTC 693 61 618 Antisense
CAGGTCGTCGCATTCGATCGTTACT 19 209 643 Antisense
TTACTCCCGAGACACTGTCGTTGGA 77 675 663 Antisense
ACGTGCCACTGATACTGTAGCTGCT 507 95 762 Antisense
GAGCTTCTTCTCTCATTGACATATC 343 389 793 Antisense
GACAGTTGTTGTTCTCAAAGCCCGT 458 367 837 Antisense
CAAAGCCCGTGGACTCGGAGGACGA 76 189 852 Antisense
ACGATGCCGGAACTGCAGATCCATT 535 93 878 Antisense
GGTCTACTTTGAATCCTGTCTACAA 172 503 968 Antisense
TAATTGGCCGTGCCCTTCTTAATAT 337 633 1088 Antisense
Sequence Source Affymetrix Proprietary Database