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[189538_s_at] guanylate kinase

Description C01B7.4 /REP_DB=WormBase Gene ID /WP=CE06728 /TR=Q17549 /GB=AAA96115.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=guanylate kinase
Cluster 6grp_highest_10_10 > 41      6grp_high1_10_10 > 03      4grp_highest_8_8 > 53      4grp_high_8_8 > 08      6grp_highest_nonorm > 61      6grp_total > 25      4grp_total > 31      6grp_highest_sub > De      6grp_cgc > 33      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 296
1 2 3 4 range
A 460
(3)
P 		219.8
(-2.7)
P 		206.7
(-3)
P 		393.8
(1.4)
P 		253
B 498.5
(3)
P 		245.1
(-2.8)
P 		235.2
(-3)
P 		344
(-0.5)
P 		263
C 470.5
(3)
P 		202.8
(-3)
P 		265.4
(-1.6)
P 		375.1
(0.9)
P 		268
avr 476.3
(3) 		222.6
(-3) 		235.8
(-2.7) 		371
(0.5) 		254

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 250
1 2 3 4 5 6 range
A 385
(0.9)
P 		433.9
(3)
P 		393.2
(1.2)
P 		343.1
(-1)
P 		329.2
(-1.6)
P 		296.5
(-3)
P 		137
B 371.1
(0.5)
P 		416.8
(3)
P 		347.2
(-0.9)
P 		308.6
(-3)
P 		333.6
(-1.6)
P 		334.5
(-1.6)
P 		108
C 546
(3)
P 		443.1
(0.2)
P 		361.4
(-1.9)
P 		364.4
(-1.9)
P 		322
(-3)
P 		375.4
(-1.6)
P 		224
avr 434
(3) 		431.3
(2.8) 		367.3
(-0.8) 		338.7
(-2.4) 		328.3
(-3) 		335.5
(-2.6) 		106
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 120
1 2 3 4 range
A 167.5
(3)
P 		47.7
(-3)
P 		54
(-2.7)
P 		57.6
(-2.5)
P 		120
B 159
(3)
P 		60.5
(-2.7)
P 		54.5
(-3)
P 		73.3
(-1.9)
P 		105
C 155.7
(3)
P 		58.3
(-3)
P 		92.5
(-0.9)
P 		63.2
(-2.7)
P 		97
avr 160.7
(3) 		55.5
(-3) 		67
(-2.3) 		64.7
(-2.5) 		105

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 131
1 2 3 4 5 6 range
A 71
(-3)
P 		154.3
(3)
P 		85.6
(-1.9)
P 		87
(-1.8)
P 		99.3
(-1)
P 		72.2
(-2.9)
P 		83
B 129.1
(2)
P 		138.7
(3)
P 		84.3
(-2.7)
P 		81.7
(-3)
P 		135.5
(2.7)
P 		124.7
(1.5)
P 		57
C 202.4
(3)
P 		135.2
(-0.1)
P 		92
(-2.1)
P 		73.3
(-3)
P 		104.2
(-1.6)
P 		125.7
(-0.6)
P 		129
avr 134.2
(2.2) 		142.7
(3) 		87.3
(-2.4) 		80.7
(-3) 		113
(0.1) 		107.5
(-0.4) 		62
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189538_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11677
Sequence Type Exemplar sequence
Representative Public ID C01B7.4 NCBI
Target Description C01B7.4 /REP_DB=WormBase Gene ID /WP=CE06728 /TR=Q17549 /GB=AAA96115.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=guanylate kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072864(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072864 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-117) (tag-117) mRNA, complete cds. 11/11 None
SNAP00000041467 ENSEMBL cdna:SNAP chromosome:CEL140:V:8795604:8798126:-1 11/11 None
GENEFINDER00000041472 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8795604:8803583:-1 11/11 None
C01B7.4 ENSEMBL cdna:known chromosome:CEL140:V:8795283:8798154:-1 gene:C01B7.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8795604-8798127(-) 98.6 100.0
Public Domain and Genome References
Gene Title guanylate kinase
Gene Symbol tag-117
Ensembl C01B7.4
Entrez Gene 3565703 Entrez gene
SwissProt Q17549 EMBL-EBI
WormBase CE06728 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.19428.1.S1_AT similar to membrane protein, palmitoylated 5 cfa
CANINE_2:CFAAFFX.25060.1.S1_AT similar to membrane protein, palmitoylated 5 cfa
DROSOPHILA_2:1639290_AT stardust dm
DROSGENOME1:144692_AT stardust dm
DROSGENOME1:150941_F_AT stardust dm
DROSOPHILA_2:1635004_AT stardust dm
DROSOPHILA_2:1623665_AT stardust dm
DROSGENOME1:151396_AT stardust dm
DROSGENOME1:144688_AT stardust dm
DROSOPHILA_2:1631732_S_AT stardust dm
DROSOPHILA_2:1631568_A_AT stardust dm
DROSGENOME1:144693_AT stardust dm
DROSGENOME1:144691_AT stardust dm
DROSGENOME1:144689_AT stardust dm
CHICKEN:GGA.11005.1.S1_S_AT similar to membrane protein, palmitoylated 5; MAGUK p55 subfamily member 5; stardust (Drosophila) gga
CHICKEN:GGAAFFX.22971.1.S1_S_AT similar to membrane protein, palmitoylated 5; MAGUK p55 subfamily member 5; stardust (Drosophila) gga
HG-U133_PLUS_2:219321_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133A:219321_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-FOCUS:219321_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133A_2:219321_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HU35KSUBA:AA248884_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HU35KSUBD:RC_AA485957_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
U133_X3P:G11968024_3P_X_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
U133_X3P:G11968024_3P_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
U133_X3P:HS.13399.0.S1_3P_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133_PLUS_2:226092_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133B:226092_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U95C:65177_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U95E:73186_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
U133_X3P:HS.199726.0.A1_3P_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133_PLUS_2:235864_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133B:235864_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U95E:86446_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133_PLUS_2:241020_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133B:241020_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133_PLUS_2:242779_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U133B:242779_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HG-U95C:61751_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HU35KSUBA:N77495_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
HU35KSUBC:RC_AA406482_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
U133_X3P:HS.109122.0.A1_3P_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
U133_X3P:HS.287334.0.A1_3P_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) hs
MOUSE430A_2:1421064_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MOE430A:1421064_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MOUSE430_2:1421064_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MG-U74BV2:113257_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MOE430A:1450113_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MOUSE430A_2:1450113_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MOUSE430_2:1450113_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) mm
MU19KSUBB:TC32816_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (Mpp5), mRNA mm
MU19KSUBC:TC36407_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (Mpp5), mRNA mm
RG-U34B:RC_AI031043_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RG-U34C:RC_AI171769_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAE230A:1374156_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAT230_2:1374156_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAE230B:1397535_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAT230_2:1397535_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAE230B:1382363_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAT230_2:1382363_AT membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAE230B:1398205_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
RAT230_2:1398205_AT Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA96115 Temporarily assigned gene name protein 117 [Caenorhabditis elegans] ref|NP_505265.1| Temporarily Assigned Gene name family member (tag-117) [Caenorhabditis elegans] 0.0
blast CAE57748 Hypothetical protein CBG00761 [Caenorhabditis briggsae] 0.0
blast XP_393395 PREDICTED: similar to ENSANGP00000010751 [Apis mellifera] 6.0E-89
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 2.0E-8
Pfam IPR008144 EMBL-EBI Guanylate kinase 1.9E-19
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 8.7E-8
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 2.0E-8
Pfam IPR008144 EMBL-EBI Guanylate kinase 1.9E-19
Sequence
Target Sequence 
>C. ELEGANS:189538_S_AT
accaaaagccacacatcgaagaccgattgttctctgtggagctgaaggagttggatgttt
gaagctgagagaccgtcttctggaatcagatcggataacgttagcttgcccagttccata
tacttctcgaaccccaaaagaaggcgaattcaacggagttcactatcattttgtatcaaa
acaaaaattccacgaagatgccaaatctggaaagtttgtcgaatttggtgaatatcaaaa
gttttggtacggaacagccaagaaggatgttgttaatgtaattgaacgtggaaaaacatg
tgtcatgacattgaaagctgagagtctcggagcgattcgatctccagatattcaaccata
cataatatttattgctgcaccatcactttatattcttcgaagacaacgagaagttgaagg
aacttttggagtgaaagatgatgagttgaaagcaattttgacacaaagcaaaagtattga
acagaaatacgggcaccttttcgatggaatcatagtcaacatcgattttgaaaaatcatt
ccgtgagctgaagcaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACCAAAAGCCACACATCGAAGACCG 285 85 1404 Antisense
TCGAAGACCGATTGTTCTCTGTGGA 330 601 1419 Antisense
TGAGAGACCGTCTTCTGGAATCAGA 61 569 1469 Antisense
AGATCGGATAACGTTAGCTTGCCCA 266 65 1491 Antisense
GAAGGCGAATTCAACGGAGTTCACT 48 333 1543 Antisense
GGAGTTCACTATCATTTTGTATCAA 696 517 1558 Antisense
GTCTCGGAGCGATTCGATCTCCAGA 300 471 1727 Antisense
GATCTCCAGATATTCAACCATACAT 467 419 1742 Antisense
GCTGCACCATCACTTTATATTCTTC 237 297 1777 Antisense
ATACGGGCACCTTTTCGATGGAATC 270 23 1890 Antisense
AAATCATTCCGTGAGCTGAAGCAAA 292 117 1936 Antisense
Sequence Source Affymetrix Proprietary Database