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[189532_at] guanylate kinase

Description T03F1.8 /REP_DB=WormBase Gene ID /WP=CE13110 /TR=P91425 /GB=AAB42236.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=guanylate kinase
Cluster 6grp_highest_10_10 > 0      6grp_high1_10_10 > 07      4grp_highest_8_8 > 32      4grp_high_8_8 > 51      6grp_highest_nonorm > 75      6grp_total > 09      4grp_total > 60      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 516
1 2 3 4 range
A 927.9
(2.4)
P
759.4
(0.4)
P
980.4
(3)
P
471.4
(-3)
P
509
B 919.3
(1.8)
P
987.6
(3)
P
903.1
(1.5)
P
649.8
(-3)
P
338
C 961.3
(3)
P
956.2
(2.9)
P
835.5
(1.4)
P
480.3
(-3)
P
481
avr 936.2
(3)
901.1
(2.5)
906.3
(2.6)
533.8
(-3)
402

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 264
1 2 3 4 5 6 range
A 937.4
(3)
P
777.4
(-1.3)
P
746.5
(-2.2)
P
894.9
(1.9)
P
715.2
(-3)
P
752.4
(-2)
P
222
B 858.4
(3)
P
782.3
(0.1)
P
701.2
(-3)
P
793.3
(0.5)
P
759.7
(-0.8)
P
791.5
(0.4)
P
157
C 965.3
(3)
P
886.6
(1.1)
P
717.3
(-3)
P
911.7
(1.7)
P
723.1
(-2.9)
P
811.2
(-0.7)
P
248
avr 920.4
(3)
815.4
(-0.2)
721.7
(-3)
866.6
(1.4)
732.7
(-2.7)
785
(-1.1)
199
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 269
1 2 3 4 range
A 337.8
(3)
P
164.8
(-0.9)
P
256.3
(1.2)
P
69
(-3)
P
269
B 293.2
(3)
P
243.9
(1.1)
P
209.3
(-0.3)
P
138.5
(-3)
P
155
C 318.2
(3)
P
274.9
(1.9)
P
291.2
(2.3)
P
81
(-3)
P
237
avr 316.4
(3)
227.9
(0.6)
252.3
(1.3)
96.2
(-3)
220

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 195
1 2 3 4 5 6 range
A 172.8
(-2.5)
P
276.5
(3)
P
162.6
(-3)
P
227
(0.4)
P
215.8
(-0.2)
P
183.2
(-1.9)
P
114
B 298.7
(2.6)
P
260.4
(0.9)
P
170.3
(-3)
P
210.1
(-1.3)
P
308.7
(3)
P
295.2
(2.4)
P
138
C 357.8
(3)
P
270.5
(0)
P
182.6
(-3)
P
183.3
(-3)
P
234
(-1.2)
P
271.6
(0)
P
175
avr 276.4
(3)
269.1
(2.6)
171.8
(-3)
206.8
(-1)
252.8
(1.6)
250
(1.5)
105
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189532_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.293
Sequence Type Exemplar sequence
Representative Public ID T03F1.8 NCBI
Target Description T03F1.8 /REP_DB=WormBase Gene ID /WP=CE13110 /TR=P91425 /GB=AAB42236.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=guanylate kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058842(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_058842 NCBI Caenorhabditis elegans T03F1.8 (T03F1.8) mRNA, complete cds. 11/11 None
GENEFINDER00000013133 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:3854248:3860577:-1 10/11 None
SNAP00000013116 ENSEMBL cdna:SNAP chromosome:CEL140:I:3859686:3860577:-1 10/11 None
T03F1.8 ENSEMBL cdna:known chromosome:CEL140:I:3859401:3862554:-1 gene:T03F1.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:3859685-3860677(-) 98.57 100.0
Public Domain and Genome References
Gene Title guanylate kinase
Ensembl T03F1.8
Entrez Gene 171963 Entrez gene
SwissProt P91425 EMBL-EBI
WormBase CE29460 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:267537_AT guanylate kinase 1 (GK-1) at
CANINE:1589784_AT similar to Guanylate kinase (GMP kinase) cfa
CANINE_2:CFA.15059.1.A1_AT similar to Guanylate kinase (GMP kinase) cfa
CANINE_2:CFAAFFX.2651.1.S1_AT similar to Guanylate kinase (GMP kinase) cfa
CANINE_2:CFAAFFX.2651.1.S1_S_AT similar to Guanylate kinase (GMP kinase) cfa
DROSOPHILA_2:1640421_AT dm
DROSGENOME1:152077_AT dm
CHICKEN:GGA.9602.1.S1_AT similar to Guk1 protein gga
PLASMODIUM_ANOPHELES:200075_S_AT guanylate kinase 1 hs
HG-U133B:200075_S_AT guanylate kinase 1 hs
HG-U133A:200075_S_AT guanylate kinase 1 hs
HG-U133_PLUS_2:200075_S_AT guanylate kinase 1 hs
HG-FOCUS:200075_S_AT guanylate kinase 1 hs
HG-U133A_2:200075_S_AT guanylate kinase 1 hs
U133_X3P:200075_S_AT guanylate kinase 1 hs
HG-U95AV2:905_AT guanylate kinase 1 hs
HC-G110:905_AT guanylate kinase 1 hs
HUGENEFL:L76200_AT guanylate kinase 1 hs
U133_X3P:G13623296_3P_S_AT guanylate kinase 1 hs
HG-U133_PLUS_2:213621_S_AT Guanylate kinase 1 hs
HG-U133A_2:213621_S_AT Guanylate kinase 1 hs
HG-FOCUS:213621_S_AT Guanylate kinase 1 hs
HG-U133A:213621_S_AT Guanylate kinase 1 hs
HG-U95AV2:41541_AT Guanylate kinase 1 hs
U133_X3P:HS.3764.1.A1_3P_A_AT Guanylate kinase 1 hs
MU11KSUBA:U53514_S_AT guanylate kinase 1 mm
MG-U74AV2:98544_AT guanylate kinase 1 mm
MOE430A:1416395_AT guanylate kinase 1 mm
MOUSE430A_2:1416395_AT guanylate kinase 1 mm
MOUSE430_2:1416395_AT guanylate kinase 1 mm
MU11KSUBB:MSA.38834.0_S_AT Guanylate kinase 1, mRNA (cDNA clone MGC:25313 IMAGE:4485215) mm
MU19KSUBB:TC27368_AT Guanylate kinase 1, mRNA (cDNA clone MGC:25313 IMAGE:4485215) mm
RG-U34A:RC_AA800291_AT guanylate kinase 1 (predicted) rn
RAE230A:1371743_AT guanylate kinase 1 (predicted) rn
RAT230_2:1371743_AT guanylate kinase 1 (predicted) rn
YEAST_2:1770082_AT Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_491242 T03F1.7 [Caenorhabditis elegans] gb|AAB42235.2| Hypothetical protein T03F1.7 [Caenorhabditis elegans] 0.0
blast CAE66633 Hypothetical protein CBG11970 [Caenorhabditis briggsae] 1.0E-171
blast NP_491243 T03F1.8 [Caenorhabditis elegans] gb|AAB42236.2| Hypothetical protein T03F1.8 [Caenorhabditis elegans] 1.0E-121
blast CAE66635 Hypothetical protein CBG11972 [Caenorhabditis briggsae] 1.0E-109
blast NP_491243 T03F1.8 [Caenorhabditis elegans] gb|AAB42236.2| Hypothetical protein T03F1.8 [Caenorhabditis elegans] 1.0E-107
blast NP_491243 T03F1.8 [Caenorhabditis elegans] gb|AAB42236.2| Hypothetical protein T03F1.8 [Caenorhabditis elegans] 1.0E-106
blast CAE66635 Hypothetical protein CBG11972 [Caenorhabditis briggsae] 1.0E-100
blast AAH59563 Guk1 protein [Danio rerio] 4.0E-55
Protein Domains
Database ID Description E-Value
Pfam IPR008144 EMBL-EBI Guanylate kinase 2.5E-51
Pfam IPR008144 EMBL-EBI Guanylate kinase 2.5E-51
Pfam IPR001737 EMBL-EBI Ribosomal RNA adenine dimethylase 3.1E-33
Sequence
Target Sequence
>C. ELEGANS:189532_AT
aaaatgccgtgccggccgattgtgctctccggaccatcgggtggaggaaaaagtacgatt
ttgacgagagccatgcaggaatacccaaatagctttgctttcagcgtttctcacacaacg
agacagccaagagccggtgaggagcacggaaaacactattacttcacggaaaaggagaag
atgcaggaaatgattaaaaataacgagtttctggagttcgccacgtttagcggaaatact
tatggaactagcaagaaaaccgtcctagaaatcgaaaatagcggaaagatctgcgttctg
gatattgagttgcaaggagttcgaaacatcaagaatagtcatctcgacgccagatacatt
ctgatccgtgccccatccatcaagcttctcgaggaaagactcagagcaagaggaaccgaa
accgaggagagcctctcgaagcgtcttcaacatgcatctgaggatttagttgaaatcgaa
aaaaatccaacgctcttcgacaaagtgattgtgaacgatgatttggaacgtgcctataag
gaattcgtcgatcttcttcgt


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AAAATGCCGTGCCGGCCGATTGTGC 419 131 52 Antisense
GACGAGAGCCATGCAGGAATACCCA 565 377 114 Antisense
CTTTCAGCGTTTCTCACACAACGAG 276 223 149 Antisense
GACAGCCAAGAGCCGGTGAGGAGCA 116 369 173 Antisense
TAACGAGTTTCTGGAGTTCGCCACG 348 637 252 Antisense
GTCATCTCGACGCCAGATACATTCT 450 467 389 Antisense
CCCATCCATCAAGCTTCTCGAGGAA 445 259 423 Antisense
CGAGGAGAGCCTCTCGAAGCGTCTT 627 247 474 Antisense
GAAGCGTCTTCAACATGCATCTGAG 507 343 489 Antisense
AAAATCCAACGCTCTTCGACAAAGT 201 115 533 Antisense
TAAGGAATTCGTCGATCTTCTTCGT 346 637 588 Antisense
Sequence Source Affymetrix Proprietary Database