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[189520_at]

Description T06A4.3 /REP_DB=WormBase Gene ID /WP=CE18212 /TR=Q9TZH2 /GB=AAC67474.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster 6grp_total > 10      4grp_total > 02      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 65
1 2 3 4 range
A 6
(-2.9)
A 		5.4
(-3)
A 		10.6
(-2.5)
A 		68.6
(3)
A 		63
B 24.2
(-0.7)
A 		12.6
(-3)
A 		27.2
(-0.1)
A 		42.9
(3)
A 		30
C 12.1
(-2.1)
A 		27.9
(-0.6)
A 		3.3
(-3)
A 		64.1
(3)
A 		61
avr 14.1
(-2.9) 		15.3
(-2.8) 		13.7
(-3) 		58.5
(3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 10.2
(-0.8)
A 		3.4
(-2.8)
A 		23.6
(3)
A 		17.8
(1.3)
A 		3
(-2.9)
A 		2.7
(-3)
A 		21
B 7.4
(-3)
A 		9.2
(-2.6)
A 		33.1
(2.9)
A 		33.4
(3)
A 		20.2
(-0)
A 		28.8
(1.9)
A 		26
C 6.4
(-2.5)
A 		51.7
(3)
A 		2.5
(-3)
A 		2.5
(-3)
A 		30.6
(0.4)
A 		18.4
(-1.1)
A 		49
avr 8
(-3) 		21.4
(3) 		19.7
(2.2) 		17.9
(1.4) 		17.9
(1.4) 		16.6
(0.9) 		13
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 2.2
(-2.3)
A 		1.2
(-3)
A 		2.8
(-1.9)
A 		10
(3)
A 		9
B 7.7
(1.5)
A 		3.1
(-3)
A 		6.3
(0.1)
A 		9.2
(3)
A 		6
C 4
(-1.3)
A 		8
(1.3)
A 		1.2
(-3)
A 		10.8
(3)
A 		10
avr 4.6
(-1.9) 		4.1
(-2.4) 		3.4
(-3) 		10
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 15
1 2 3 4 5 6 range
A 1.9
(-1.4)
A 		1.2
(-2.3)
A 		5.1
(3)
A 		4.5
(2.2)
A 		0.9
(-2.7)
A 		0.7
(-3)
A 		4
B 2.6
(-3)
A 		3.1
(-2.6)
A 		8
(1)
A 		8.8
(1.6)
A 		8.2
(1.1)
A 		10.7
(3)
A 		8
C 2.4
(-2.3)
A 		15.8
(3)
A 		0.6
(-3)
A 		0.5
(-3)
A 		9.9
(0.7)
A 		6.2
(-0.8)
A 		15
avr 2.3
(-3) 		6.7
(3) 		4.6
(0.1) 		4.6
(0.1) 		6.3
(2.5) 		5.9
(1.9) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189520_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3
Sequence Type Exemplar sequence
Representative Public ID T06A4.3 NCBI
Target Description T06A4.3 /REP_DB=WormBase Gene ID /WP=CE18212 /TR=Q9TZH2 /GB=AAC67474.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026440
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
GENEFINDER00000004754 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:763677:770627:1 None
T06A4.3a ENSEMBL cdna:known chromosome:CEL140:I:763335:770706:1 gene:T06A4.3 A 
NM_001026440 NCBI Caenorhabditis elegans T06A4.3a (carboxypeptidase) mRNA, complete cds. None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:763676-770721(+) 100.0 100.0
Public Domain and Genome References
Ensembl T06A4.3
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_001021611 T06A4.3a [Caenorhabditis elegans] gb|AAT81187.1| Hypothetical protein T06A4.3a [Caenorhabditis elegans] 0.0
blast CAE61323 Hypothetical protein CBG05160 [Caenorhabditis briggsae] 0.0
blast NP_001021612 T06A4.3b [Caenorhabditis elegans] gb|AAT81188.1| Hypothetical protein T06A4.3b [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 1.2E-10
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 4.5E-39
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 5.5E-34
Pfam IPR003146 EMBL-EBI Peptidase M14A, carboxypeptidase activation peptide 2.1E-6
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 1.2E-10
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 8.3E-35
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 5.5E-34
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001021611.1 1 7-29
T06A4.3a 1 7-29
GENEFINDER00000004754 1 7-29
Sequence
Target Sequence 
>C. ELEGANS:189520_AT
tttttctcggtctccgatactttctcggctaccaactttttctcggccaccaactttttc
tcggccacagatttttttctcggccattaatttttgacggccaccgaaattttttcggtc
accgatatttttcacggccattgatatttttttcggtcaccgatactttctcggccacaa
atattttctcggccaccgaaatttttcgcggtcatctatattttctcggcctcagccatc
gatatttttctggaccgtctagtttttttttggcggccaagccccaaaagctcgcggatt
ccgattcggcgacggcaccgaaggatcatgtttcgatgtccgacacgcgtgcaaacgatg
ggttcaggaacgggaggagctgtgcaggacggtgccaattttcatgcgcgagaactgtgc
ctactcttgcaatttctgttgatttttttggtgtgccacttctttttttctgtacatata
tccattttgtcttctacat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTTTCTCGGTCTCCGATACTTTCT 556 673 1481 Antisense
TCTCGGCCACAGATTTTTTTCTCGG 211 611 1539 Antisense
TTTCTCGGCCATTAATTTTTGACGG 363 671 1556 Antisense
GGTCACCGATATTTTTCACGGCCAT 339 503 1597 Antisense
CACGGCCATTGATATTTTTTTCGGT 239 199 1613 Antisense
TTTCGGTCACCGATACTTTCTCGGC 494 669 1631 Antisense
GCCACAAATATTTTCTCGGCCACCG 334 279 1654 Antisense
CGCGGTCATCTATATTTTCTCGGCC 503 255 1687 Antisense
TCGATATTTTTCTGGACCGTCTAGT 448 603 1719 Antisense
TTTTGGCGGCCAAGCCCCAAAAGCT 706 663 1748 Antisense
CATATATCCATTTTGTCTTCTACAT 287 215 1955 Antisense
Sequence Source Affymetrix Proprietary Database