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[189499_at] aminotransferase

Description T01C8.4 /REP_DB=WormBase Gene ID /WP=CE07461 /TR=Q22066 /GB=AAB00577.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=aminotransferase
Cluster 6grp_total > 21      4grp_total > 21      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 35
1 2 3 4 range
A 6.1
(-2.4)
A 		12.4
(3)
A 		11.3
(2.1)
A 		5.4
(-3)
A 		7
B 23.7
(3)
A 		2.5
(-3)
A 		6.5
(-1.9)
A 		6.8
(-1.8)
A 		21
C 11.8
(-2.1)
A 		22.6
(0)
A 		7.5
(-3)
A 		37.3
(3)
A 		30
avr 13.9
(1.1) 		12.5
(0) 		8.4
(-3) 		16.5
(3) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 23
1 2 3 4 5 6 range
A 7.6
(-1.6)
A 		17.1
(1)
A 		24.7
(3)
A 		6.5
(-1.9)
A 		5.4
(-2.2)
A 		2.4
(-3)
A 		22
B 12.7
(2.7)
A 		13.3
(3)
A 		5.2
(-1.5)
A 		2.5
(-3)
A 		2.7
(-2.9)
A 		3.5
(-2.4)
A 		11
C 1.8
(-3)
A 		5.3
(-0.5)
A 		4.9
(-0.8)
A 		3.3
(-1.9)
A 		4.1
(-1.4)
A 		10.2
(3)
A 		8
avr 7.4
(-0.5) 		11.9
(3) 		11.6
(2.8) 		4.1
(-3) 		4.1
(-3) 		5.4
(-2) 		8
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 7
1 2 3 4 range
A 2.2
(0.8)
A 		2.7
(2.2)
A 		3
(3)
A 		0.8
(-3)
A 		2
B 7.5
(3)
A 		0.6
(-3)
A 		1.5
(-2.2)
A 		1.4
(-2.3)
A 		7
C 3.9
(-1)
A 		6.5
(3)
A 		2.6
(-3)
A 		6.3
(2.7)
A 		4
avr 4.5
(3) 		3.3
(-0.4) 		2.4
(-3) 		2.8
(-1.9) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6
1 2 3 4 5 6 range
A 1.4
(-2.1)
A 		6.1
(3)
A 		5.4
(2.2)
A 		1.7
(-1.8)
A 		1.6
(-1.9)
A 		0.6
(-3)
A 		6
B 4.4
(3)
A 		4.4
(3)
A 		1.3
(-2)
A 		0.7
(-3)
A 		1.1
(-2.4)
A 		1.3
(-2)
A 		4
C 0.7
(-3)
A 		1.6
(-1)
A 		1.2
(-1.9)
A 		0.7
(-3)
A 		1.3
(-1.7)
A 		3.4
(3)
A 		3
avr 2.2
(-0.6) 		4
(3) 		2.6
(0.2) 		1
(-3) 		1.3
(-2.4) 		1.8
(-1.4) 		3
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189499_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17581
Sequence Type Exemplar sequence
Representative Public ID T01C8.4 NCBI
Target Description T01C8.4 /REP_DB=WormBase Gene ID /WP=CE07461 /TR=Q22066 /GB=AAB00577.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=aminotransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078307(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078307 NCBI Caenorhabditis elegans T01C8.4 (aminotransferase) mRNA, complete cds. 11/11 None
SNAP00000021220 ENSEMBL cdna:SNAP chromosome:CEL140:X:16787545:16788465:-1 11/11 None
GENEFINDER00000021226 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:16787545:16788465:-1 11/11 None
T01C8.4 ENSEMBL cdna:known chromosome:CEL140:X:16787545:16789138:-1 gene:T01C8.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:16787544-16789138(-) 100.0 100.0
Public Domain and Genome References
Gene Title aminotransferase
Ensembl T01C8.4
Entrez Gene 187948 Entrez gene
SwissProt Q22066 EMBL-EBI
WormBase CE07461 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6520 amino acid metabolism inferred from electronic annotation QuickGO AmiGO
9058 biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8483 transaminase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB00577 Hypothetical protein T01C8.4 [Caenorhabditis elegans] ref|NP_510708.1| T01C8.4 [Caenorhabditis elegans] 0.0
blast CAE69898 Hypothetical protein CBG16248 [Caenorhabditis briggsae] 1.0E-122
blast AAB00577 Hypothetical protein T01C8.4 [Caenorhabditis elegans] ref|NP_510708.1| T01C8.4 [Caenorhabditis elegans] 1.0E-121
blast AAB00578 Hypothetical protein T01C8.5 [Caenorhabditis elegans] ref|NP_510709.1| T01C8.5 [Caenorhabditis elegans] sp|Q22067|AATC_CAEEL Probable aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate oxaloacetate transaminase-1) 1.0E-119
blast CAE69898 Hypothetical protein CBG16248 [Caenorhabditis briggsae] 2.0E-79
Protein Families
Method ID Description E-Value
ec AATC_HUMAN (P17174) Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase-1) 1.0E-110
ec AATC_HUMAN (P17174) Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase-1) 1.0E-179
Protein Domains
Database ID Description E-Value
Pfam IPR004839 EMBL-EBI Aminotransferase, class I and II 5.0E-42
Pfam IPR004839 EMBL-EBI Aminotransferase, class I and II 1.0E-37
Sequence
Target Sequence 
>C. ELEGANS:189499_AT
gattagcttctggcgacgctgatgcagatgcttgggctgttcggttctttgtcgaacagg
gtttggaaatgattgtctctcaatctttctcaaagaattttgggctttacaatgatcgtg
ttggaagccttactgtgatcgtgaacaaaccaagtcatattgcgaacctaaaatcccaac
tgacacttgttaatgtttctaatttttctaaccctccagcttacggagcacgtattgtgc
atgagattctcaagtcgccgaagtacagagaacaatggcaaaattccattaaaatgatgg
cttttcgtattaagaaaacaagacaagaactgattcgagagttgaatatgcttcaaactt
ctggaaaatgggatcgtattactcaacaatcggggttgttcagttataccggattgacgc
cttgtcaagtcgaccatctcatagcccatcacaagatctaccttctcagtgacggtcgta
ttaatatctgcgggc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTAGCTTCTGGCGACGCTGATGC 677 429 527 Antisense
TGCAGATGCTTGGGCTGTTCGGTTC 358 577 549 Antisense
ATTGTCTCTCAATCTTTCTCAAAGA 287 5 598 Antisense
GTTGGAAGCCTTACTGTGATCGTGA 310 435 646 Antisense
GCGAACCTAAAATCCCAACTGACAC 574 287 688 Antisense
TAACCCTCCAGCTTACGGAGCACGT 687 637 735 Antisense
AGTTATACCGGATTGACGCCTTGTC 615 61 928 Antisense
TTGTCAAGTCGACCATCTCATAGCC 174 707 948 Antisense
ATAGCCCATCACAAGATCTACCTTC 115 23 967 Antisense
ATCTACCTTCTCAGTGACGGTCGTA 480 29 982 Antisense
GACGGTCGTATTAATATCTGCGGGC 169 377 997 Antisense
Sequence Source Affymetrix Proprietary Database