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[189495_at] cysteine protease

Description F26E4.3 /REP_DB=WormBase Gene ID /WP=CE17714 /TR=P90850 /GB=CAB03007.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cysteine protease
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 21      4grp_high_8_8 > 59      6grp_highest_nonorm > 41      6grp_total > 22      4grp_total > 60      6grp_highest_sub > De      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1015
1 2 3 4 range
A 833.2
(1.8)
P 		1021.9
(3)
P 		889.6
(2.2)
P 		61.7
(-3)
A 		960
B 1077.1
(3)
P 		930
(2.1)
P 		997.8
(2.5)
P 		66
(-3)
P 		1011
C 1026.3
(3)
P 		836.6
(1.8)
P 		993.6
(2.8)
P 		97.7
(-3)
A 		929
avr 978.9
(3) 		929.5
(2.7) 		960.3
(2.9) 		75.1
(-3) 		904

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 894
1 2 3 4 5 6 range
A 651.4
(1.1)
P 		836.1
(3)
P 		687.4
(1.5)
P 		758.8
(2.2)
P 		520.5
(-0.2)
P 		239.5
(-3)
P 		597
B 774.1
(0.9)
P 		805.5
(1.1)
P 		1084.5
(3)
P 		634.8
(-0)
P 		479.4
(-1.1)
P 		191
(-3)
P 		894
C 956.1
(3)
P 		958.4
(3)
P 		839
(2)
P 		837
(1.9)
P 		419
(-1.7)
P 		265.4
(-3)
P 		693
avr 793.9
(2.3) 		866.7
(3) 		870.3
(3) 		743.5
(1.8) 		473
(-0.7) 		232
(-3) 		638
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 337
1 2 3 4 range
A 303.4
(3)
P 		221.8
(1.3)
P 		232.6
(1.6)
P 		9
(-3)
A 		294
B 343.5
(3)
P 		229.7
(0.9)
P 		231.2
(1)
P 		14.1
(-3)
P 		329
C 339.7
(2.9)
P 		240.5
(1.1)
P 		346.3
(3)
P 		16.5
(-3)
A 		330
avr 328.9
(3) 		230.7
(1.1) 		270
(1.9) 		13.2
(-3) 		316

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 296
1 2 3 4 5 6 range
A 120.1
(-1.4)
P 		297.4
(3)
P 		149.7
(-0.7)
P 		192.4
(0.4)
P 		157.1
(-0.5)
P 		58.3
(-3)
P 		239
B 269.4
(3)
P 		268.1
(3)
P 		263.3
(2.8)
P 		168.1
(-0.1)
P 		194.8
(0.7)
P 		71.2
(-3)
P 		198
C 354.4
(3)
P 		292.4
(1.6)
P 		213.5
(-0.2)
P 		168.3
(-1.2)
P 		135.6
(-1.9)
P 		88.9
(-3)
P 		266
avr 248
(1.9) 		286
(3) 		208.8
(0.8) 		176.3
(-0.1) 		162.5
(-0.5) 		72.8
(-3) 		213
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189495_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1634
Sequence Type Exemplar sequence
Representative Public ID F26E4.3 NCBI
Target Description F26E4.3 /REP_DB=WormBase Gene ID /WP=CE17714 /TR=P90850 /GB=CAB03007.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cysteine protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060192(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060192 NCBI Caenorhabditis elegans F26E4.3 (F26E4.3) mRNA, complete cds. 11/11 None
SNAP00000026223 ENSEMBL cdna:SNAP chromosome:CEL140:I:9770693:9774437:-1 11/11 None
GENEFINDER00000026239 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9770693:9775905:-1 11/11 None
F26E4.3 ENSEMBL cdna:known chromosome:CEL140:I:9770081:9776066:-1 gene:F26E4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9770623-9775997(-) 100.0 100.0
Public Domain and Genome References
Gene Title cysteine protease
Ensembl F26E4.3
Entrez Gene 172827 Entrez gene
SwissProt P90850 EMBL-EBI
WormBase CE17714 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.17212.1.S1_S_AT similar to P3ECSL cfa
DROSOPHILA_2:1641413_S_AT dm
DROSGENOME1:153218_AT dm
CHICKEN:GGAAFFX.11339.1.S1_AT similar to lipocalin 7; glucocorticoid-inducible protein gga
HG-U133_PLUS_2:219058_X_AT tubulointerstitial nephritis antigen-like 1 hs
HG-FOCUS:219058_X_AT tubulointerstitial nephritis antigen-like 1 hs
HG-U133A:219058_X_AT tubulointerstitial nephritis antigen-like 1 hs
HG-U133A_2:219058_X_AT tubulointerstitial nephritis antigen-like 1 hs
U133_X3P:G11545917_3P_X_AT tubulointerstitial nephritis antigen-like 1 hs
U133_X3P:219058_3P_X_AT tubulointerstitial nephritis antigen-like 1 hs
HG-U95E:90686_R_AT tubulointerstitial nephritis antigen-like 1 hs
MU11KSUBA:C80271_RC_AT tubulointerstitial nephritis antigen-like mm
MU11KSUBA:C80271_RC_G_AT tubulointerstitial nephritis antigen-like mm
MU11KSUBB:MSA.7029.0_S_AT tubulointerstitial nephritis antigen-like mm
MG-U74AV2:160613_AT tubulointerstitial nephritis antigen-like mm
MOE430A:1417109_AT tubulointerstitial nephritis antigen-like mm
MOUSE430A_2:1417109_AT tubulointerstitial nephritis antigen-like mm
MOUSE430_2:1417109_AT tubulointerstitial nephritis antigen-like mm
MU19KSUBA:TC15388_S_AT Tubulointerstitial nephritis antigen-like, mRNA (cDNA clone MGC:11828 IMAGE:3596560) mm
MU19KSUBA:TC21895_F_AT Tubulointerstitial nephritis antigen-like, mRNA (cDNA clone MGC:11828 IMAGE:3596560) mm
MU11KSUBA:D18782_RC_AT Tubulointerstitial nephritis antigen-like, mRNA (cDNA clone MGC:11828 IMAGE:3596560) mm
RG-U34C:RC_AI231321_AT lipocalin 7 rn
RG-U34C:RC_AI179892_AT lipocalin 7 rn
RAE230A:1367650_AT lipocalin 7 rn
RAT230_2:1367650_AT lipocalin 7 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03007 Hypothetical protein F26E4.3 [Caenorhabditis elegans] ref|NP_492593.1| F26E4.3 [Caenorhabditis elegans] 0.0
blast CAE60233 Hypothetical protein CBG03805 [Caenorhabditis briggsae] 0.0
blast XP_535330 PREDICTED: similar to P3ECSL [Canis familiaris] 3.0E-99
Protein Domains
Database ID Description E-Value
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.5E-78
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 3.8E-55
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.5E-78
Sequence
Target Sequence 
>C. ELEGANS:189495_AT
aggagtcgtcggagatcattgttatccatatgtgtctggacaaagccgagaacctgggca
ttgcctgattccaaagagagattatacaaatcgacaaggacttcggtgtccaagtggatc
tcaagatagtaccgcttttaaaatgactccgccgtacaaagtgtcaagtcgtgaggaaga
tattcaaactgaacttatgacaaatggcccagtacaagcaacttttgtagttcacgagga
tttctttatgtatgctggaggagtttatcaacattctgatcttgctgctcaaaaaggagc
atcttccgttgcagagggatatcattcggttcgagttttgggatggggagttgatcactc
aacaggaaaaccaatcaaatactggttgtgtgccaattcatggggaactcagtggggaga
agatggatatttcaaagttttaagaggagagaatcattgtgaaattgaaagctttgttat
tggagcctggggcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGGAGTCGTCGGAGATCATTGTTAT 230 57 927 Antisense
GTGTCTGGACAAAGCCGAGAACCTG 286 485 958 Antisense
GAACCTGGGCATTGCCTGATTCCAA 200 347 976 Antisense
AGGACTTCGGTGTCCAAGTGGATCT 238 55 1023 Antisense
TACCGCTTTTAAAATGACTCCGCCG 72 649 1056 Antisense
GACTCCGCCGTACAAAGTGTCAAGT 508 361 1071 Antisense
AATGGCCCAGTACAAGCAACTTTTG 99 161 1129 Antisense
TCAACATTCTGATCTTGCTGCTCAA 645 629 1194 Antisense
AAAGGAGCATCTTCCGTTGCAGAGG 279 121 1219 Antisense
GCAGAGGGATATCATTCGGTTCGAG 545 311 1237 Antisense
GCTTTGTTATTGGAGCCTGGGGCAA 27 281 1397 Antisense
Sequence Source Affymetrix Proprietary Database