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[189477_s_at] alpha-mannosidase

Description F58H1.1 /REP_DB=WormBase Gene ID /WP=CE06025 /TR=Q21010 /GB=CAB00104.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=alpha-mannosidase
Cluster 6grp_highest_10_10 > 35      6grp_high1_10_10 > 40      4grp_highest_8_8 > 35      4grp_high_8_8 > 48      6grp_highest_nonorm > 76      6grp_total > 40      4grp_total > 55      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 789
1 2 3 4 range
A 1397.6
(3)
P 		981.6
(-1.8)
P 		1029
(-1.3)
P 		877.9
(-3)
P 		520
B 1536.2
(3)
P 		935.5
(-3)
P 		1158
(-0.8)
P 		1025.8
(-2.1)
P 		601
C 1465.7
(3)
P 		747.1
(-3)
P 		1193.6
(0.7)
P 		951.1
(-1.3)
P 		719
avr 1466.5
(3) 		888.1
(-3) 		1126.9
(-0.5) 		951.6
(-2.3) 		578

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 691
1 2 3 4 5 6 range
A 1061.2
(-1.7)
P 		1409.6
(3)
P 		974.9
(-2.9)
P 		1272
(1.1)
P 		967.2
(-3)
P 		1049.5
(-1.9)
P 		442
B 1104.1
(0.1)
P 		963
(-1.8)
P 		1317
(3)
P 		1147.4
(0.7)
P 		877.1
(-3)
P 		875.3
(-3)
P 		442
C 1033.3
(-1)
P 		1146.5
(-0.1)
P 		1499.2
(3)
P 		1145
(-0.1)
P 		808.4
(-3)
P 		1035.7
(-1)
P 		691
avr 1066.2
(-0.1) 		1173
(1.6) 		1263.7
(3) 		1188.1
(1.8) 		884.2
(-3) 		986.8
(-1.4) 		380
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 380
1 2 3 4 range
A 508.9
(3)
P 		213.1
(-1.7)
P 		269
(-0.8)
P 		128.5
(-3)
P 		380
B 489.9
(3)
P 		231
(-2.7)
P 		268.3
(-1.9)
P 		218.6
(-3)
P 		271
C 485.2
(3)
P 		214.8
(-2)
P 		416
(1.7)
P 		160.4
(-3)
P 		325
avr 494.7
(3) 		219.6
(-2.1) 		317.8
(-0.3) 		169.2
(-3) 		326

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 306
1 2 3 4 5 6 range
A 195.6
(-3)
P 		501.3
(3)
P 		212.3
(-2.7)
P 		322.6
(-0.5)
P 		291.9
(-1.1)
P 		255.5
(-1.8)
P 		306
B 384.2
(3)
P 		320.5
(-1.8)
P 		319.8
(-1.8)
P 		303.9
(-3)
P 		356.3
(0.9)
P 		326.4
(-1.3)
P 		80
C 383
(3)
P 		349.8
(1.7)
P 		381.6
(2.9)
P 		230.3
(-3)
P 		261.6
(-1.8)
P 		346.7
(1.6)
P 		153
avr 320.9
(-1) 		390.5
(3) 		304.6
(-1.9) 		285.6
(-3) 		303.3
(-2) 		309.5
(-1.6) 		105
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189477_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14122
Sequence Type Exemplar sequence
Representative Public ID F58H1.1 NCBI
Target Description F58H1.1 /REP_DB=WormBase Gene ID /WP=CE06025 /TR=Q21010 /GB=CAB00104.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=alpha-mannosidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073594(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073594 NCBI Caenorhabditis elegans F58H1.1 (alpha-mannosidase) mRNA, complete cds. 11/11 None
SNAP00000006507 ENSEMBL cdna:SNAP chromosome:CEL140:V:11930420:11935745:-1 11/11 None
GENEFINDER00000006521 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11930323:11931504:-1 11/11 None
F58H1.1 ENSEMBL cdna:known chromosome:CEL140:V:11930260:11935815:-1 gene:F58H1.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11930419-11935815(-) 98.48 100.0
Public Domain and Genome References
Gene Title alpha-mannosidase
Ensembl F58H1.1
Entrez Gene 179632 Entrez gene
SwissProt Q21010 EMBL-EBI
WormBase CE06025 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.11999.1.S1_AT similar to mannosidase, alpha, class 2A, member 1 cfa
CANINE_2:CFAAFFX.12001.1.S1_S_AT similar to mannosidase, alpha, class 2A, member 1 cfa
DROSOPHILA_2:1626112_AT Mannosidase II dm
DROSGENOME1:142163_S_AT Mannosidase II dm
DROSGENOME1:142162_AT Mannosidase II dm
CHICKEN:GGAAFFX.155.1.S1_AT similar to Alpha-mannosidase II (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha-mannosidase II) (Mannosidase alpha class 2A member 1) gga
CHICKEN:GGAAFFX.156.1.S1_AT similar to Alpha-mannosidase II (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha-mannosidase II) (Mannosidase alpha class 2A member 1) gga
HG-FOCUS:205105_AT mannosidase, alpha, class 2A, member 1 hs
HG-U133A:205105_AT mannosidase, alpha, class 2A, member 1 hs
HG-U133_PLUS_2:205105_AT mannosidase, alpha, class 2A, member 1 hs
HG-U133A_2:205105_AT mannosidase, alpha, class 2A, member 1 hs
HU35KSUBD:RC_T95828_AT mannosidase, alpha, class 2A, member 1 hs
HUGENEFL:D63998_AT mannosidase, alpha, class 2A, member 1 hs
U133_X3P:G4758697_3P_AT mannosidase, alpha, class 2A, member 1 hs
HG-U95AV2:39663_AT mannosidase, alpha, class 2A, member 1 hs
HU35KSUBA:RC_AA236982_AT Mannosidase, alpha, class 2A, member 1 hs
U133_X3P:HS.63368.0.A1_3P_AT Mannosidase, alpha, class 2A, member 1 hs
U133_X3P:HS.204295.0.S1_3P_X_AT Mannosidase, alpha, class 2A, member 1 hs
U133_X3P:HS.204295.0.S1_3P_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U133_PLUS_2:226538_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U133B:226538_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U133_PLUS_2:235103_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U133B:235103_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U95E:77854_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U95C:52233_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U95C:56108_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U95C:56309_R_AT Mannosidase, alpha, class 2A, member 1 hs
HG-U95D:88860_AT Mannosidase, alpha, class 2A, member 1 hs
HU35KSUBB:RC_N34044_AT Mannosidase, alpha, class 2A, member 1 hs
HU35KSUBC:RC_W86997_AT Mannosidase, alpha, class 2A, member 1 hs
MU11KSUBB:X61172_S_AT mannosidase 2, alpha 1 mm
MG-U74AV2:104628_AT mannosidase 2, alpha 1 mm
MOE430A:1448647_AT mannosidase 2, alpha 1 mm
MOUSE430A_2:1448647_AT mannosidase 2, alpha 1 mm
MOUSE430_2:1448647_AT mannosidase 2, alpha 1 mm
MU19KSUBC:TC38515_S_AT Mannosidase 2, alpha 1 (Man2a1), mRNA mm
MU19KSUBC:TC41844_S_AT Mannosidase 2, alpha 1 (Man2a1), mRNA mm
RG-U34A:M24353_AT mannosidase 2, alpha 1 rn
RG-U34A:M24353_G_AT mannosidase 2, alpha 1 rn
RG-U34B:RC_AI045939_I_AT mannosidase 2, alpha 1 rn
RAE230B:1382594_AT Mannosidase 2, alpha 1 rn
RAT230_2:1382594_AT Mannosidase 2, alpha 1 rn
RG-U34C:RC_AA858860_AT Mannosidase 2, alpha 1 rn
RG-U34C:RC_AI070822_AT Mannosidase 2, alpha 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
5975 carbohydrate metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4559 alpha-mannosidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB00104 Hypothetical protein F58H1.1 [Caenorhabditis elegans] ref|NP_505995.1| F58H1.1 [Caenorhabditis elegans] 0.0
blast CAE75350 Hypothetical protein CBG23330 [Caenorhabditis briggsae] 0.0
blast AAH72937 MGC80473 protein [Xenopus laevis] 0.0
Protein Domains
Database ID Description E-Value
scop a.4.5.C-terminal fragment of elongation factor SelB All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; C-terminal fragment of elongation factor SelB 6.19999980926514
Pfam IPR000602 EMBL-EBI Glycoside hydrolase, family 38 1.0E-126
Pfam IPR000602 EMBL-EBI Glycoside hydrolase, family 38 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505995.1 1 7-26
F58H1.1 1 7-26
GENEFINDER00000006521 1 319-338
Sequence
Target Sequence 
>C. ELEGANS:189477_S_AT
ggcacaggctctcggagttagcagtctctcgtcgggacaaattgaaataatgcttgatcg
acgacttagttcagatgacaacagaggtcttcagcaaggagttagagacaacaaacgaac
agttgcacatttccgtattgttattgagccgatgtcttcatcgagtggtaataagaagga
agaacgagttggattccattcacatgttggtcatctcgctacgtggtctcttcattatcc
tcttgtcaaaatgattggagatgcaacaccaaaatctatttcttcgaaaaatgtggaaca
agagctgaactgtgacctgcatctagtgacatttagaacactggcatcgccgacaactta
cgaagccaacgaaagatctacggcagctgagaagaaagcagcgatggtgatgcatagagt
tgttccagactgtagatccaggcttaccctcccagacacgtcatgcttagctactggatt
agaaattgagccactcaaattgatctcgacactgaagtctgcgaaaaaaacgtcactaac
caatctttatgaaggaaacaaggctgaacaattccgactcca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCACAGGCTCTCGGAGTTAGCAGT 170 535 2826 Antisense
TTAGCAGTCTCTCGTCGGGACAAAT 701 679 2843 Antisense
GAACAGTTGCACATTTCCGTATTGT 12 351 2942 Antisense
ATTCACATGTTGGTCATCTCGCTAC 51 13 3023 Antisense
TCTCTTCATTATCCTCTTGTCAAAA 311 613 3052 Antisense
AGAGCTGAACTGTGACCTGCATCTA 253 69 3126 Antisense
GACATTTAGAACACTGGCATCGCCG 119 371 3153 Antisense
GCATCGCCGACAACTTACGAAGCCA 284 307 3169 Antisense
CAGACTGTAGATCCAGGCTTACCCT 639 205 3251 Antisense
CTCCCAGACACGTCATGCTTAGCTA 628 233 3274 Antisense
ACAAGGCTGAACAATTCCGACTCCA 443 113 3383 Antisense
Sequence Source Affymetrix Proprietary Database