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[189472_at] potassium channel

Description C32C4.1 /REP_DB=WormBase Gene ID /WP=CE05344 /TR=Q18351 /GB=CAA98109.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=potassium channel
Cluster 6grp_highest_10_10 > 71      6grp_high1_10_10 > 29      4grp_highest_8_8 > 46      4grp_high_8_8 > 02      6grp_highest_nonorm > 80      6grp_total > 27      4grp_total > 14      6grp_highest_sub > De      6grp_high1_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 263
1 2 3 4 range
A 284
(2.1)
P 		157.1
(-2.4)
P 		138.7
(-3)
P 		309.2
(3)
P 		171
B 292.6
(0.6)
P 		158.6
(-2.6)
P 		139.7
(-3)
P 		395.1
(3)
P 		255
C 276.5
(0.6)
P 		132
(-3)
P 		144
(-2.7)
P 		371.6
(3)
P 		240
avr 284.4
(1) 		149.2
(-2.8) 		140.8
(-3) 		358.6
(3) 		218

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 224
1 2 3 4 5 6 range
A 290.5
(3)
P 		228.3
(1.2)
P 		165.3
(-0.7)
P 		85.5
(-3)
P 		175.9
(-0.4)
P 		189.3
(0)
P 		205
B 309.7
(3)
P 		247.8
(0.7)
P 		163.3
(-2.4)
P 		148
(-3)
P 		181.6
(-1.8)
P 		173.3
(-2.1)
P 		162
C 280.9
(3)
P 		222.6
(0.3)
P 		155.6
(-2.7)
P 		150.1
(-3)
P 		172.6
(-2)
P 		181.6
(-1.6)
P 		131
avr 293.7
(3) 		232.9
(0.8) 		161.4
(-1.8) 		127.9
(-3) 		176.7
(-1.2) 		181.4
(-1.1) 		166
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 71
1 2 3 4 range
A 103.4
(3)
P 		34.1
(-3)
P 		36.3
(-2.8)
P 		45.3
(-2)
P 		69
B 93.3
(3)
P 		39.2
(-2.3)
P 		32.4
(-3)
P 		84.2
(2.1)
P 		61
C 91.5
(3)
P 		38
(-3)
P 		50.2
(-1.6)
P 		62.7
(-0.2)
P 		54
avr 96.1
(3) 		37.1
(-3) 		39.6
(-2.7) 		64.1
(-0.3) 		59

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 86
1 2 3 4 5 6 range
A 53.6
(0.2)
P 		81.2
(3)
P 		36
(-1.6)
P 		21.7
(-3)
P 		53.1
(0.2)
P 		46.1
(-0.5)
P 		60
B 107.8
(3)
P 		82.5
(0.8)
P 		39.7
(-3)
P 		39.2
(-3)
P 		73.8
(0)
P 		64.6
(-0.8)
P 		69
C 104.1
(3)
P 		67.9
(0.1)
P 		39.6
(-2.2)
P 		30.2
(-3)
P 		55.8
(-0.9)
P 		60.8
(-0.5)
P 		74
avr 88.5
(3) 		77.2
(1.8) 		38.4
(-2.2) 		30.4
(-3) 		60.9
(0.1) 		57.2
(-0.2) 		58
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189472_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13068
Sequence Type Exemplar sequence
Representative Public ID C32C4.1 NCBI
Target Description C32C4.1 /REP_DB=WormBase Gene ID /WP=CE05344 /TR=Q18351 /GB=CAA98109.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=potassium channel
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073324(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073324 NCBI Caenorhabditis elegans C32C4.1 (C32C4.1) mRNA, complete cds. 11/11 None
GENEFINDER00000003075 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10644615:10647378:1 10/11 None
C32C4.1 ENSEMBL cdna:known chromosome:CEL140:V:10644615:10647699:1 gene:C32C4.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000003070 8/11 Cross Hyb Matching Probes None
SNAP00000003071 2/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10644984-10647332(+) 100.0 100.0
Public Domain and Genome References
Gene Title potassium channel
Ensembl C32C4.1
Entrez Gene 183120 Entrez gene
SwissProt Q18351 EMBL-EBI
WormBase CE37877 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.6166.1.S1_AT similar to potassium voltage-gated channel, subfamily F, member 1 cfa
CHICKEN:GGAAFFX.10527.1.S1_AT similar to potassium voltage-gated channel, subfamily F, member 1; potassium channel KH1; potassium channel Kv5.1 gga
HG-U133_PLUS_2:210263_AT potassium voltage-gated channel, subfamily F, member 1 hs
HG-U133A:210263_AT potassium voltage-gated channel, subfamily F, member 1 hs
HG-FOCUS:210263_AT potassium voltage-gated channel, subfamily F, member 1 hs
HG-U133A_2:210263_AT potassium voltage-gated channel, subfamily F, member 1 hs
HU35KSUBB:RC_R45529_AT potassium voltage-gated channel, subfamily F, member 1 hs
HU35KSUBD:RC_Z38223_S_AT potassium voltage-gated channel, subfamily F, member 1 hs
U133_X3P:G12001823_3P_AT potassium voltage-gated channel, subfamily F, member 1 hs
HG-U95AV2:39268_AT potassium voltage-gated channel, subfamily F, member 1 hs
MU11KSUBB:MSA.13804.0_AT potassium voltage-gated channel, subfamily F, member 1 mm
MG-U74BV2:105507_AT potassium voltage-gated channel, subfamily F, member 1 mm
MOE430B:1454768_AT potassium voltage-gated channel, subfamily F, member 1 mm
MOUSE430_2:1454768_AT potassium voltage-gated channel, subfamily F, member 1 mm
MOE430B:1441300_AT potassium voltage-gated channel, subfamily F, member 1 mm
MOUSE430_2:1441300_AT potassium voltage-gated channel, subfamily F, member 1 mm
RN-U34:M81783_AT potassium voltage-gated channel, subfamily F, member 1 rn
RG-U34A:M81783_AT potassium voltage-gated channel, subfamily F, member 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8076 voltage-gated potassium channel complex inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98109 Hypothetical protein C32C4.1 [Caenorhabditis elegans] ref|NP_505725.3| C32C4.1 [Caenorhabditis elegans] 0.0
blast CAE64863 Hypothetical protein CBG09661 [Caenorhabditis briggsae] 0.0
blast AAA83447 Hypothetical protein F44A2.2 [Caenorhabditis elegans] ref|NP_505407.2| F44A2.2 [Caenorhabditis elegans] 8.0E-78
blast AAA83447 Hypothetical protein F44A2.2 [Caenorhabditis elegans] ref|NP_505407.2| F44A2.2 [Caenorhabditis elegans] 8.0E-75
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 9.3E-43
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 8.2E-40
Pfam IPR005821 EMBL-EBI Ion transport protein 6.7E-40
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505725.3 4 212-234,293-315,397-419,458-480
C32C4.1 4 212-234,293-315,397-419,458-480
GENEFINDER00000003075 4 212-234,293-315,397-419,456-478
Sequence
Target Sequence 
>C. ELEGANS:189472_AT
ttgatctctctacaattcttccattttatttggaaatctgtctcccactatttggagtag
agtcccgacttaaagaatttacaggtgcaatgttggttgttcgagttcttcgagttctac
gtatggccagggttttcaaattggccagatacagtacaagtctgcagacattcggacaca
cacttcagtcatcaatcacagaattgagcatgctgagcatgtttttgatcacaggaattg
tattcttctcaacaattatgtactatcttgagaaagacgaaccacatacagatttctaca
gtatccccgccggctgttggtggtgtgtggtcacaatggctacggtaggatatggagatg
caaaaccagtaacaactcttggaaaactcgtggcaacttctacatcaatttgcggaatta
tagttttggcgtttccaatttctatgatcgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGATCTCTCTACAATTCTTCCATT 260 705 899 Antisense
ATTTGGAAATCTGTCTCCCACTATT 135 17 926 Antisense
CAATGTTGGTTGTTCGAGTTCTTCG 319 181 986 Antisense
GAGTTCTTCGAGTTCTACGTATGGC 671 395 1001 Antisense
GTTCTACGTATGGCCAGGGTTTTCA 154 443 1012 Antisense
TGCAGACATTCGGACACACACTTCA 707 577 1061 Antisense
ACACACTTCAGTCATCAATCACAGA 427 111 1076 Antisense
ATACAGATTTCTACAGTATCCCCGC 218 25 1184 Antisense
GGCTGTTGGTGGTGTGTGGTCACAA 26 539 1210 Antisense
AACTCGTGGCAACTTCTACATCAAT 472 139 1283 Antisense
GGCGTTTCCAATTTCTATGATCGTT 586 541 1326 Antisense
Sequence Source Affymetrix Proprietary Database