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[189466_at] homeobox protein

Description ZK993.1 /REP_DB=WormBase Gene ID /WP=CE23489 /TR=Q9N4L2 /GB=AAF40014.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=homeobox protein
Cluster 6grp_high1_10_10 > 19      4grp_highest_8_8 > 60      4grp_high_8_8 > 26      6grp_total > 05      4grp_total > 38      6grp_cgc > 03      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 101
1 2 3 4 range
A 156.5
(3)
P 		82.2
(-2.3)
P 		73
(-3)
P 		149.1
(2.5)
P 		84
B 170.4
(3)
P 		98
(-1.3)
P 		69.1
(-3)
P 		99.8
(-1.2)
P 		101
C 158.6
(3)
P 		145.5
(2.1)
P 		70.7
(-3)
P 		100.8
(-0.9)
P 		88
avr 161.8
(3) 		108.6
(-0.5) 		70.9
(-3) 		116.6
(0) 		91

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 93
1 2 3 4 5 6 range
A 134.7
(2.9)
P 		136.3
(3)
P 		63.8
(-2.5)
P 		71.1
(-2)
P 		57.6
(-3)
M 		65.9
(-2.4)
P 		79
B 100.4
(3)
P 		89.7
(1.4)
P 		59
(-3)
P 		73.4
(-0.9)
P 		90
(1.5)
P 		63.2
(-2.4)
P 		41
C 122.1
(3)
P 		112.7
(2.3)
P 		58.1
(-1.9)
P 		84.2
(0.1)
P 		98.8
(1.2)
P 		43.4
(-3)
P 		79
avr 119.1
(3) 		112.9
(2.4) 		60.3
(-2.7) 		76.2
(-1.2) 		82.1
(-0.6) 		57.5
(-3) 		62
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 41
1 2 3 4 range
A 57
(3)
P 		17.8
(-3)
P 		19.1
(-2.8)
P 		21.8
(-2.4)
P 		39
B 54.3
(3)
P 		24.2
(-1.7)
P 		16
(-3)
P 		21.3
(-2.2)
P 		38
C 52.5
(3)
P 		41.8
(1.2)
P 		24.6
(-1.7)
P 		17
(-3)
P 		36
avr 54.6
(3) 		27.9
(-1.6) 		19.9
(-3) 		20
(-3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 35
1 2 3 4 5 6 range
A 24.8
(-1.1)
P 		48.5
(3)
P 		13.9
(-3)
P 		18
(-2.3)
P 		17.4
(-2.4)
M 		16
(-2.6)
P 		35
B 34.9
(2.5)
P 		29.9
(1.2)
P 		14.3
(-3)
P 		19.4
(-1.6)
P 		36.6
(3)
P 		23.6
(-0.5)
P 		22
C 45.3
(3)
P 		34.4
(0.9)
P 		14.8
(-2.9)
P 		16.9
(-2.5)
P 		32
(0.4)
P 		14.5
(-3)
P 		31
avr 35
(2.3) 		37.6
(3) 		14.3
(-3) 		18.1
(-2) 		28.7
(0.7) 		18
(-2) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189466_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17
Sequence Type Exemplar sequence
Representative Public ID ZK993.1 NCBI
Target Description ZK993.1 /REP_DB=WormBase Gene ID /WP=CE23489 /TR=Q9N4L2 /GB=AAF40014.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=homeobox protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058422(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058422 NCBI Caenorhabditis elegans ZK993.1 (ZK993.1) mRNA, complete cds. 11/11 None
GENEFINDER00000037213 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:1128361:1131631:1 11/11 None
SNAP00000037212 ENSEMBL cdna:SNAP chromosome:CEL140:I:1128382:1131636:1 11/11 None
ZK993.1 ENSEMBL cdna:known chromosome:CEL140:I:1128347:1131739:1 gene:ZK993.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1128360-1131636(+) 100.0 100.0
Public Domain and Genome References
Gene Title homeobox protein
Gene Symbol ceh-45
Ensembl ZK993.1
Entrez Gene 171689 Entrez gene
SwissProt Q9N4L2 EMBL-EBI
WormBase CE23489 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF40014 Hypothetical protein ZK993.1 [Caenorhabditis elegans] ref|NP_490823.1| ZK993.1 [Caenorhabditis elegans] 1.0E-104
blast AAF40014 Hypothetical protein ZK993.1 [Caenorhabditis elegans] ref|NP_490823.1| ZK993.1 [Caenorhabditis elegans] 1.0E-103
blast AAF40014 Hypothetical protein ZK993.1 [Caenorhabditis elegans] ref|NP_490823.1| ZK993.1 [Caenorhabditis elegans] 1.0E-100
blast CAE63937 Hypothetical protein CBG08515 [Caenorhabditis briggsae] 4.0E-83
blast CAE63937 Hypothetical protein CBG08515 [Caenorhabditis briggsae] 2.0E-79
blast AAG31170 goosecoid transcription factor Gsc [Strongylocentrotus purpuratus] ref|NP_999663.1| goosecoid transcription factor [Strongylocentrotus purpuratus] 2.0E-22
Protein Domains
Database ID Description E-Value
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 3.99999987306209E-21
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 1.99999993653105E-21
Pfam IPR001356 EMBL-EBI Homeobox 1.5E-27
Pfam IPR001356 EMBL-EBI Homeobox 1.5E-27
Sequence
Target Sequence 
>C. ELEGANS:189466_AT
tccacatcaacctcattctcaattgacacattgctctcgaacccgttggccggaattccg
cagcttcacaattttcaagatccatttggagcagtgggagccgcagcggcggcttctgcc
ctgccatggcagtttcatccggctaattatccgtttttctcaatgctctgcggaccacta
atgcctccattcatggctccatatcaccatcaacactacgcctcccgacgaaaacgccgg
catcgtaccattttcagcgaggagcagttgaacattttggagaccacattttcaacgaca
cactacccggacgctacgacgagagaagagctcgcggttcagtgctcattgaaggaagaa
agagttgaggtctggttcaaaaatcgtcgggcaaaagagcgcaagcagaagaaggacgac
agtcggacttctaagcacagcggagacgattccgaatgtgacgagagcgacgaggacacc
cga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCACATCAACCTCATTCTCAATTG 248 589 106 Antisense
CAATTGACACATTGCTCTCGAACCC 60 181 125 Antisense
AATTCCGCAGCTTCACAATTTTCAA 418 177 159 Antisense
CTTCTGCCCTGCCATGGCAGTTTCA 211 221 218 Antisense
GGCAGTTTCATCCGGCTAATTATCC 507 535 233 Antisense
AATTATCCGTTTTTCTCAATGCTCT 484 175 250 Antisense
TGGCTCCATATCACCATCAACACTA 496 545 299 Antisense
CCGGCATCGTACCATTTTCAGCGAG 334 265 342 Antisense
AAGAGCTCGCGGTTCAGTGCTCATT 66 155 431 Antisense
GACAGTCGGACTTCTAAGCACAGCG 431 369 523 Antisense
TGACGAGAGCGACGAGGACACCCGA 270 571 564 Antisense
Sequence Source Affymetrix Proprietary Database