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[189453_s_at] carboxypeptidase

Description F59A3.1 /REP_DB=WormBase Gene ID /WP=CE28480 /TR=P91359 /GB=AAB37821.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster 6grp_highest_10_10 > 12      6grp_high1_10_10 > 20      4grp_highest_8_8 > 45      4grp_high_8_8 > 01      6grp_highest_nonorm > 61      6grp_total > 40      4grp_total > 15      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 328
1 2 3 4 range
A 444.1
(0.9)
P 		266.9
(-3)
P 		283.5
(-2.6)
P 		540.9
(3)
P 		274
B 467.6
(3)
P 		256.2
(-3)
P 		269.9
(-2.6)
P 		277.7
(-2.4)
P 		211
C 400.3
(3)
P 		213
(-3)
P 		316.6
(0.3)
P 		395.2
(2.8)
P 		187
avr 437.3
(3) 		245.4
(-3) 		290
(-1.6) 		404.6
(2) 		192

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 319
1 2 3 4 5 6 range
A 445
(3)
P 		419.4
(2.3)
P 		401.5
(1.7)
P 		404.5
(1.8)
P 		270.7
(-2)
P 		236.8
(-3)
P 		208
B 473.5
(2.7)
P 		408.1
(1.1)
P 		483.6
(3)
P 		457.4
(2.3)
P 		255.2
(-2.8)
P 		249
(-3)
P 		235
C 397.1
(0.7)
P 		489.5
(2.4)
P 		361.6
(-0)
P 		522
(3)
P 		203.1
(-3)
P 		294.9
(-1.3)
P 		319
avr 438.5
(2.4) 		439
(2.4) 		415.6
(1.7) 		461.3
(3) 		243
(-3) 		260.2
(-2.5) 		218
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 104
1 2 3 4 range
A 161.7
(3)
P 		57.9
(-3)
P 		74.1
(-2.1)
P 		79.2
(-1.8)
P 		104
B 149.1
(3)
P 		63.3
(-2.7)
P 		62.5
(-2.8)
P 		59.2
(-3)
P 		90
C 132.5
(3)
P 		61.2
(-3)
P 		110.3
(1.1)
P 		66.6
(-2.5)
P 		71
avr 147.8
(3) 		60.8
(-3) 		82.3
(-1.5) 		68.3
(-2.5) 		87

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 107
1 2 3 4 5 6 range
A 82
(-1.4)
P 		149.2
(3)
P 		87.4
(-1.1)
P 		102.6
(-0.1)
P 		81.7
(-1.4)
P 		57.7
(-3)
P 		92
B 164.8
(3)
P 		135.8
(0.6)
P 		117.4
(-1)
P 		121.1
(-0.6)
P 		103.7
(-2.1)
P 		92.9
(-3)
P 		72
C 147.2
(2.8)
P 		149.4
(3)
P 		92
(-1.1)
P 		105
(-0.2)
P 		65.7
(-3)
P 		98.7
(-0.6)
P 		84
avr 131.3
(1.7) 		144.8
(3) 		98.9
(-1.5) 		109.6
(-0.4) 		83.7
(-2.9) 		83.1
(-3) 		62
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189453_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2422
Sequence Type Exemplar sequence
Representative Public ID F59A3.1 NCBI
Target Description F59A3.1 /REP_DB=WormBase Gene ID /WP=CE28480 /TR=P91359 /GB=AAB37821.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059218(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059218 NCBI Caenorhabditis elegans F59A3.1 (carboxypeptidase) mRNA, complete cds. 11/11 None
GENEFINDER00000013456 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:5525846:5529522:1 11/11 None
SNAP00000013447 ENSEMBL cdna:SNAP chromosome:CEL140:I:5525906:5529522:1 9/11 None
F59A3.1 ENSEMBL cdna:known chromosome:CEL140:I:5520392:5529756:1 gene:F59A3.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:5520393-5529522(+) 100.0 100.0
Public Domain and Genome References
Gene Title carboxypeptidase
Ensembl F59A3.1
Entrez Gene 172206 Entrez gene
SwissProt P91359 EMBL-EBI
WormBase CE30548 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4181 metallocarboxypeptidase activity inferred from electronic annotation QuickGO AmiGO
4182 carboxypeptidase A activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB37821 Hypothetical protein F59A3.1 [Caenorhabditis elegans] ref|NP_491619.2| F59A3.1 [Caenorhabditis elegans] 0.0
blast CAE67078 Hypothetical protein CBG12487 [Caenorhabditis briggsae] 0.0
blast NP_031780 carboxypeptidase D [Mus musculus] sp|O89001|CBPD_MOUSE Carboxypeptidase D precursor (Metallocarboxypeptidase D) (gp180) dbj|BAA33371.1| gp180-carboxypeptidase D-like enzyme [Mus musculus] 8.0E-99
Protein Domains
Database ID Description E-Value
Pfam IPR008575 EMBL-EBI Peptidase M14B 2.3E-60
Pfam IPR008575 EMBL-EBI Peptidase M14B 2.3E-60
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 7.7E-62
Pfam IPR008575 EMBL-EBI Peptidase M14B 2.3E-60
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_491619.2 1 952-969
F59A3.1 1 952-969
GENEFINDER00000013456 1 678-695
SNAP00000013447 1 658-675
Sequence
Target Sequence 
>C. ELEGANS:189453_S_AT
aactgataacttggacgcgcttcttgttcaaattggatgttgctatgaaaatatggccag
tggacatctgtattctgaaaatcagagagcaataaaaacagcattaattgaaagaagtcg
tggtgttcgaataattggtggaactgatggaatgagtgtatcagtggatcatatgcataa
acgtttaccacttttgggtggaagacggtttgttcctttaccaaatggagaacatttggt
taaagttagaacgcctggtgggcaaatgcatgcacaatttgcagttatatcagatcgaac
tccaactgttgaaaaatttgttggagtacaatcatcaaatatggttataatcacaattgc
atcaattttaatgattatctgctgcacatttatgtgtcgtcaaagagtaacgtccgtcct
gaatcggcgaggtttctttaatgga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACTGATAACTTGGACGCGCTTCTT 346 141 2436 Antisense
GACGCGCTTCTTGTTCAAATTGGAT 487 381 2449 Antisense
TGGCCAGTGGACATCTGTATTCTGA 159 545 2489 Antisense
GAGTGTATCAGTGGATCATATGCAT 427 401 2589 Antisense
TGCATAAACGTTTACCACTTTTGGG 652 571 2609 Antisense
GAACGCCTGGTGGGCAAATGCATGC 276 347 2684 Antisense
ATCAGATCGAACTCCAACTGTTGAA 702 27 2724 Antisense
GATTATCTGCTGCACATTTATGTGT 407 429 2808 Antisense
GTCGTCAAAGAGTAACGTCCGTCCT 452 471 2831 Antisense
CGTCCGTCCTGAATCGGCGAGGTTT 3 247 2846 Antisense
GAATCGGCGAGGTTTCTTTAATGGA 425 327 2856 Antisense
Sequence Source Affymetrix Proprietary Database