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[189401_s_at] carboxylesterase

Description ZC376.2 /REP_DB=WormBase Gene ID /WP=CE15195 /TR=Q23273 /GB=CAB00884.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster 6grp_highest_10_10 > 17      6grp_high1_10_10 > 60      4grp_high_8_8 > 49      6grp_highest_nonorm > 90      6grp_total > 60      4grp_total > 53      6grp_highest_sub > 04      6grp_high1_sub > 04      6grp_total_sub > Hat      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 202
1 2 3 4 range
A 191.8
(3)
P 		163
(1.9)
P 		103.4
(-0.3)
P 		29.3
(-3)
A 		163
B 213.9
(3)
P 		125.2
(-0.2)
P 		104.7
(-1)
P 		48.1
(-3)
A 		166
C 231.3
(3)
P 		138.6
(-0.1)
P 		192.6
(1.7)
P 		51.1
(-3)
P 		180
avr 212.3
(3) 		142.3
(0.5) 		133.6
(0.2) 		42.8
(-3) 		170

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 140
1 2 3 4 5 6 range
A 133.3
(0.2)
P 		97.8
(-1.3)
P 		135.8
(0.4)
P 		195.6
(3)
P 		102.6
(-1.1)
P 		60.1
(-3)
P 		136
B 78.2
(-1.4)
P 		90.8
(-0.5)
P 		129.5
(2.2)
P 		140.2
(3)
P 		100
(0.1)
P 		55.9
(-3)
P 		84
C 104.5
(0.2)
P 		66
(-3)
P 		84.2
(-1.5)
P 		138.1
(3)
P 		67.2
(-2.9)
P 		97.2
(-0.4)
P 		72
avr 105.3
(-0.6) 		84.9
(-2) 		116.5
(0.1) 		158
(3) 		89.9
(-1.7) 		71.1
(-3) 		87
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 72
1 2 3 4 range
A 69.8
(3)
P 		35.4
(-0.2)
P 		27
(-0.9)
P 		4.3
(-3)
A 		66
B 68.2
(3)
P 		30.9
(-0.9)
P 		24.3
(-1.5)
P 		10.2
(-3)
A 		58
C 76.6
(3)
P 		39.9
(-0.2)
P 		67.1
(2.2)
P 		8.6
(-3)
P 		68
avr 71.5
(3) 		35.4
(-0.4) 		39.5
(-0) 		7.7
(-3) 		64

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 35
1 2 3 4 5 6 range
A 24.6
(-1.3)
P 		34.8
(0.5)
P 		29.6
(-0.4)
P 		49.6
(3)
P 		31
(-0.2)
P 		14.6
(-3)
P 		35
B 27.2
(-1.1)
P 		30.2
(-0.2)
P 		31.4
(0.2)
P 		37.1
(1.9)
P 		40.6
(3)
P 		20.9
(-3)
P 		20
C 38.7
(3)
P 		20.1
(-3)
P 		21.4
(-2.6)
P 		27.8
(-0.5)
P 		21.8
(-2.5)
P 		32.5
(1)
P 		19
avr 30.2
(-0.1) 		28.4
(-0.8) 		27.5
(-1.1) 		38.2
(3) 		31.1
(0.3) 		22.7
(-3) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189401_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14200
Sequence Type Exemplar sequence
Representative Public ID ZC376.2 NCBI
Target Description ZC376.2 /REP_DB=WormBase Gene ID /WP=CE15195 /TR=Q23273 /GB=CAB00884.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=carboxylesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074108(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074108 NCBI Caenorhabditis elegans ZC376.2 (carboxylesterase) mRNA, complete cds. 11/11 None
SNAP00000015355 ENSEMBL cdna:SNAP chromosome:CEL140:V:14174291:14179939:-1 11/11 None
GENEFINDER00000015365 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:14174291:14179939:-1 11/11 None
ZC376.2 ENSEMBL cdna:known chromosome:CEL140:V:14174291:14177901:-1 gene:ZC376.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14174290-14177887(-) 100.0 100.0
Public Domain and Genome References
Gene Title carboxylesterase
Ensembl ZC376.2
Entrez Gene 179917 Entrez gene
SwissProt Q23273 EMBL-EBI
WormBase CE36904 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB00884 Hypothetical protein ZC376.2 [Caenorhabditis elegans] ref|NP_506509.3| ZC376.2 [Caenorhabditis elegans] 0.0
blast CAB03277 Hypothetical protein ZC376.3 [Caenorhabditis elegans] emb|CAB00887.1| Hypothetical protein ZC376.3 [Caenorhabditis elegans] ref|NP_506508.1| ZC376.3 [Caenorhabditis elegans] 0.0
blast CAE61007 Hypothetical protein CBG04745 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 2.7E-125
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 7.7E-57
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-124
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 4.7E-124
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506509.3 1 636-658
ZC376.2 1 636-658
SNAP00000015355 1 1090-1112
GENEFINDER00000015365 1 1124-1146
Sequence
Target Sequence 
>C. ELEGANS:189401_S_AT
gaactttggtgatccttcacctttggaggatcaggaatgggcgcagtataccccggaaaa
acgagaatattttttgatcgattttgataagaactttacaatgcctggaatgaaagatca
ctattacccaaaggctttggagttttggagtacatgtggaagcaagtctttcaaggaaca
cttttctccgtcagtcgatatatttataatcggaaatctcttgaatccaattatgtctca
tttgaatcataatgaaactggccccgataagacttttgagcaatttgataaattgtataa
cgaacgggaagagtttttgaaacttctaaaagctgtaaggaaattggaaattcaaaagaa
aatgtggagaggtcgaagttccaaagatttaatgctgaaagagcttgtggatttggagaa
aataaacgaagaagagcaagaaactggagctaatttccttctcataatatttggtgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAACTTTGGTGATCCTTCACCTTTG 288 349 1512 Antisense
GGAGGATCAGGAATGGGCGCAGTAT 172 517 1536 Antisense
GCGCAGTATACCCCGGAAAAACGAG 226 275 1552 Antisense
ATAAGAACTTTACAATGCCTGGAAT 655 1 1598 Antisense
AGATCACTATTACCCAAAGGCTTTG 207 65 1626 Antisense
TCAAGGAACACTTTTCTCCGTCAGT 439 633 1682 Antisense
CACTTTTCTCCGTCAGTCGATATAT 473 197 1690 Antisense
CTCTTGAATCCAATTATGTCTCATT 396 229 1729 Antisense
GAATCATAATGAAACTGGCCCCGAT 298 327 1755 Antisense
AACTGGCCCCGATAAGACTTTTGAG 673 95 1767 Antisense
ATTTCCTTCTCATAATATTTGGTGG 325 17 1964 Antisense
Sequence Source Affymetrix Proprietary Database