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[189381_at] carboxypeptidase

Description T27A8.1 /REP_DB=WormBase Gene ID /WP=CE18294 /TR=Q22825 /GB=CAA92226.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 03      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 80      6grp_total > 25      4grp_total > 46      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 412
1 2 3 4 range
A 495
(3)
P
247.9
(-1.2)
P
143.4
(-3)
P
159.9
(-2.7)
P
352
B 547.3
(3)
P
232.2
(-1.7)
P
172.6
(-2.5)
P
141.4
(-3)
P
406
C 528.4
(3)
P
209.8
(-1.9)
P
151
(-2.8)
P
135.6
(-3)
P
393
avr 523.6
(3)
230
(-1.7)
155.7
(-2.8)
145.6
(-3)
378

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 195
1 2 3 4 5 6 range
A 314.9
(3)
P
250.6
(0.8)
P
197.7
(-1)
P
166.1
(-2.1)
P
169
(-2)
P
140.9
(-3)
P
174
B 289.6
(3)
P
267.8
(2.1)
P
275.9
(2.4)
P
186
(-1.4)
P
149
(-3)
P
194.9
(-1)
P
141
C 317.8
(3)
P
286.8
(2)
P
251.7
(1)
P
182.1
(-1.2)
P
123.3
(-3)
P
193.3
(-0.8)
P
195
avr 307.4
(3)
268.4
(1.5)
241.8
(0.5)
178.1
(-1.8)
147.1
(-3)
176.4
(-1.9)
160
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 157
1 2 3 4 range
A 180.2
(3)
P
53.8
(-1.8)
P
37.5
(-2.5)
P
23.4
(-3)
P
157
B 174.5
(3)
P
57.3
(-1.9)
P
40
(-2.6)
P
30.1
(-3)
P
144
C 174.9
(3)
P
60.3
(-1.5)
P
52.6
(-1.8)
P
22.9
(-3)
P
152
avr 176.5
(3)
57.1
(-1.7)
43.4
(-2.3)
25.5
(-3)
151

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 84
1 2 3 4 5 6 range
A 58.1
(-0.4)
P
89.1
(3)
P
43.1
(-2)
P
42.1
(-2.1)
P
51
(-1.2)
P
34.3
(-3)
P
55
B 100.8
(3)
P
89.2
(1.6)
P
67
(-0.9)
P
49.3
(-3)
P
60.5
(-1.7)
P
72.7
(-0.3)
P
52
C 117.8
(3)
P
87.5
(0.8)
P
64.1
(-1)
P
36.6
(-3)
P
39.9
(-2.8)
P
64.7
(-0.9)
P
81
avr 92.2
(3)
88.6
(2.6)
58.1
(-1.1)
42.7
(-3)
50.5
(-2.1)
57.2
(-1.2)
50
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189381_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17414
Sequence Type Exemplar sequence
Representative Public ID T27A8.1 NCBI
Target Description T27A8.1 /REP_DB=WormBase Gene ID /WP=CE18294 /TR=Q22825 /GB=CAA92226.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=carboxypeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078224(9)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_078224 NCBI Caenorhabditis elegans T27A8.1 (carboxypeptidase) mRNA, complete cds. 9/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000006731 8/11 Cross Hyb Matching Probes None
SNAP00000006721 8/11 Cross Hyb Matching Probes None
T27A8.1 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:16049799-16054438(+) 100.0 100.0
Public Domain and Genome References
Gene Title carboxypeptidase
Entrez Gene 181684 Entrez gene
SwissProt Q22825 EMBL-EBI
WormBase CE35629 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261505_AT carboxypeptidase D, putative at
CANINE:1592451_AT similar to carboxypeptidase D precursor cfa
CANINE_2:CFA.16183.1.A1_S_AT similar to carboxypeptidase D precursor cfa
CANINE_2:CFAAFFX.29043.1.S1_AT similar to carboxypeptidase D precursor cfa
DROSGENOME1:144346_AT silver dm
DROSOPHILA_2:1633733_A_AT silver dm
DROSGENOME1:143503_AT silver dm
CHICKEN:GGA.7594.1.S1_AT carboxypeptidase D gga
CHICKEN:GGAAFFX.21160.1.S1_S_AT carboxypeptidase D gga
HG-U133_PLUS_2:201941_AT carboxypeptidase D hs
HG-U133A_2:201941_AT carboxypeptidase D hs
HG-FOCUS:201941_AT carboxypeptidase D hs
HG-U133A:201941_AT carboxypeptidase D hs
HG-U133A:201942_S_AT carboxypeptidase D hs
HG-U133_PLUS_2:201942_S_AT carboxypeptidase D hs
HG-U133A_2:201942_S_AT carboxypeptidase D hs
HG-U133A:201943_S_AT carboxypeptidase D hs
HG-U133_PLUS_2:201943_S_AT carboxypeptidase D hs
HG-U133A_2:201943_S_AT carboxypeptidase D hs
HU35KSUBA:RC_AA463697_S_AT carboxypeptidase D hs
HU35KSUBB:RC_R64113_AT carboxypeptidase D hs
HU35KSUBC:RC_AA281950_AT carboxypeptidase D hs
HUGENEFL:U90914_AT carboxypeptidase D hs
U133_X3P:G8051580_3P_A_AT carboxypeptidase D hs
U133_X3P:G3641620_3P_A_AT carboxypeptidase D hs
U133_X3P:HS.5057.0.A4_3P_AT carboxypeptidase D hs
U133_X3P:HS.5057.0.A3_3P_AT carboxypeptidase D hs
HG-U133A_2:201940_AT carboxypeptidase D hs
HG-U133_PLUS_2:201940_AT carboxypeptidase D hs
HG-U133A:201940_AT carboxypeptidase D hs
HG-U95AV2:34876_AT carboxypeptidase D hs
HG-U95B:42828_AT carboxypeptidase D hs
HG-U133_PLUS_2:229600_S_AT Carboxypeptidase D hs
HG-U133B:229600_S_AT Carboxypeptidase D hs
HG-U95E:67574_AT Carboxypeptidase D hs
HG-U95E:89298_AT Carboxypeptidase D hs
HU35KSUBA:RC_AA458655_AT Carboxypeptidase D hs
U133_X3P:HS.5057.1.A1_3P_AT Carboxypeptidase D hs
MOE430A:1418018_AT carboxypeptidase D mm
MOUSE430A_2:1418018_AT carboxypeptidase D mm
MOUSE430_2:1418018_AT carboxypeptidase D mm
MG-U74BV2:106997_AT carboxypeptidase D mm
MG-U74CV2:139289_AT carboxypeptidase D mm
MG-U74CV2:134194_AT carboxypeptidase D mm
MG-U74AV2:160655_AT carboxypeptidase D mm
MOE430A:1455009_AT carboxypeptidase D mm
MOUSE430A_2:1455009_AT carboxypeptidase D mm
MOUSE430_2:1455009_AT carboxypeptidase D mm
MOE430A:1418020_S_AT carboxypeptidase D mm
MOUSE430A_2:1418020_S_AT carboxypeptidase D mm
MOUSE430_2:1418020_S_AT carboxypeptidase D mm
MOE430A:1418019_AT carboxypeptidase D mm
MOUSE430A_2:1418019_AT carboxypeptidase D mm
MOUSE430_2:1418019_AT carboxypeptidase D mm
MOE430B:1442212_AT carboxypeptidase D mm
MOUSE430_2:1442212_AT carboxypeptidase D mm
MOE430B:1447392_S_AT carboxypeptidase D mm
MOUSE430_2:1447392_S_AT carboxypeptidase D mm
MU11KSUBA:AA450768_S_AT Carboxypeptidase D (Cpd), mRNA mm
MG-U74AV2:104467_AT Carboxypeptidase D (Cpd), mRNA mm
MG-U74BV2:117166_AT Carboxypeptidase D (Cpd), mRNA mm
MOE430A:1434547_AT Carboxypeptidase D (Cpd), mRNA mm
MOUSE430A_2:1434547_AT Carboxypeptidase D (Cpd), mRNA mm
MOUSE430_2:1434547_AT Carboxypeptidase D (Cpd), mRNA mm
MU19KSUBA:TC21719_AT Carboxypeptidase D (Cpd), mRNA mm
MU19KSUBA:TC23977_AT Carboxypeptidase D (Cpd), mRNA mm
MU19KSUBB:TC33874_AT Carboxypeptidase D (Cpd), mRNA mm
RG-U34A:U62897_AT carboxypeptidase D rn
RAE230A:1369215_A_AT carboxypeptidase D rn
RAT230_2:1369215_A_AT carboxypeptidase D rn
RAE230A:1389924_AT Carboxypeptidase D rn
RAT230_2:1389924_AT Carboxypeptidase D rn
RAE230B:1397954_AT Carboxypeptidase D rn
RAT230_2:1397954_AT Carboxypeptidase D rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4181 metallocarboxypeptidase activity inferred from electronic annotation QuickGO AmiGO
4182 carboxypeptidase A activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92226 Hypothetical protein T27A8.1 [Caenorhabditis elegans] ref|NP_510625.2| T27A8.1 [Caenorhabditis elegans] 0.0
blast CAE70000 Hypothetical protein CBG16407 [Caenorhabditis briggsae] 0.0
blast XP_415836 PREDICTED: similar to carboxypeptidase D [Gallus gallus] 3.0E-96
Protein Domains
Database ID Description E-Value
Pfam IPR000834 EMBL-EBI Peptidase M14, carboxypeptidase A 3.9E-52
Pfam IPR008575 EMBL-EBI Peptidase M14B 8.7E-63
Sequence
Target Sequence
>C. ELEGANS:189381_AT
aagttcatcgatctcatccatggttttgcaaatttcacccgattttccagagctatccat
ggtctagtaattgatgcagacactggagaaggaatcgtaaatgctacagtgagcatagat
gagagagcaaaaattgttgtgagctatggagaaggcgagttttggagacttgcaaacatg
ggaaaatacgatctcaccttcgaccacagtgactactatcctgtcactcaaactgtgcac
gtcactccacaagaccgttccccgtacattgaagtccgtctgcaaaggataataccacgt
tcgcgaccagtccttatcccgacaaaatcagttccaaacaaagacgagtacaatgttgat
aattcaaataacaaagatctccgtattgtgacaatgtcctcctccg


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AAGTTCATCGATCTCATCCATGGTT 344 157 1057 Antisense
TGCAAATTTCACCCGATTTTCCAGA 597 575 1083 Antisense
TTTCCAGAGCTATCCATGGTCTAGT 631 669 1100 Antisense
GAAAATACGATCTCACCTTCGACCA 317 353 1238 Antisense
CCTTCGACCACAGTGACTACTATCC 265 269 1253 Antisense
ACTACTATCCTGTCACTCAAACTGT 163 101 1268 Antisense
TCACTCAAACTGTGCACGTCACTCC 335 627 1280 Antisense
CCCGTACATTGAAGTCCGTCTGCAA 589 257 1317 Antisense
AAGGATAATACCACGTTCGCGACCA 225 161 1341 Antisense
ACCAGTCCTTATCCCGACAAAATCA 141 85 1362 Antisense
CGTATTGTGACAATGTCCTCCTCCG 490 247 1438 Antisense
Sequence Source Affymetrix Proprietary Database