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[189370_at] EGF-like domain

Description Y69H2.12 /REP_DB=WormBase Gene ID /WP=CE22830 /TR=Q9U1T8 /GB=CAB63409.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=EGF-like domain
Cluster 6grp_total > 44      4grp_total > 25      6grp_cgc > 45      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 96
1 2 3 4 range
A 4.6
(-3)
A 		35.9
(1.5)
A 		27.8
(0.4)
A 		45.9
(3)
P 		41
B 15.6
(-0.1)
A 		25.6
(3)
A 		6.3
(-3)
A 		19.1
(1)
A 		19
C 2.1
(-3)
A 		30.4
(-1.2)
A 		27.8
(-1.4)
A 		98.2
(3)
A 		96
avr 7.4
(-3) 		30.6
(-0) 		20.6
(-1.3) 		54.4
(3) 		47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 24
1 2 3 4 5 6 range
A 26.2
(3)
A 		2.3
(-3)
A 		22.1
(2)
A 		3.1
(-2.8)
A 		6.4
(-2)
A 		3.1
(-2.8)
A 		24
B 9.8
(-1.3)
A 		15.3
(0.2)
A 		26
(3)
A 		7.4
(-1.9)
A 		3.3
(-3)
A 		14.3
(-0.1)
A 		23
C 17.6
(1.5)
A 		16.1
(1)
A 		4.6
(-2.5)
A 		3
(-3)
A 		15.7
(0.9)
A 		22.5
(3)
A 		20
avr 17.9
(3) 		11.2
(0) 		17.6
(2.9) 		4.5
(-3) 		8.5
(-1.2) 		13.3
(0.9) 		13
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 1.7
(-3)
A 		7.8
(3)
A 		7.3
(2.5)
A 		6.7
(1.9)
P 		6
B 5
(1.4)
A 		6.3
(3)
A 		1.5
(-3)
A 		4.1
(0.3)
A 		5
C 0.7
(-3)
A 		8.7
(0)
A 		9.7
(0.4)
A 		16.6
(3)
A 		16
avr 2.5
(-3) 		7.6
(1.6) 		6.2
(0.4) 		9.1
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 7
1 2 3 4 5 6 range
A 4.8
(3)
A 		0.8
(-2.9)
A 		4.8
(3)
A 		0.8
(-2.9)
A 		1.9
(-1.2)
A 		0.7
(-3)
A 		4
B 3.4
(-0.5)
A 		5.1
(1.6)
A 		6.3
(3)
A 		1.9
(-2.3)
A 		1.3
(-3)
A 		5.3
(1.8)
A 		5
C 6.5
(2.1)
A 		4.9
(0.7)
A 		1.2
(-2.5)
A 		0.6
(-3)
A 		5.1
(0.9)
A 		7.5
(3)
A 		7
avr 4.9
(3) 		3.6
(0.9) 		4.1
(1.7) 		1.1
(-3) 		2.8
(-0.3) 		4.5
(2.4) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189370_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14423
Sequence Type Exemplar sequence
Representative Public ID Y69H2.12 NCBI
Target Description Y69H2.12 /REP_DB=WormBase Gene ID /WP=CE22830 /TR=Q9U1T8 /GB=CAB63409.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=EGF-like domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075239(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075239 NCBI Caenorhabditis elegans Y69H2.12 (Y69H2.12) mRNA, complete cds. 11/11 None
SNAP00000002596 ENSEMBL cdna:SNAP chromosome:CEL140:V:18633167:18658739:1 11/11 None
GENEFINDER00000002613 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:18643083:18658587:1 11/11 None
Y69H2.12 ENSEMBL cdna:known chromosome:CEL140:V:18652917:18656675:1 gene:Y69H2.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:18652916-18656675(+) 100.0 100.0
Public Domain and Genome References
Gene Title EGF-like domain
Gene Symbol tag-336
Ensembl Y69H2.12
Entrez Gene 190561 Entrez gene
SwissProt Q9U1T8 EMBL-EBI
WormBase CE22830 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB63409 Hypothetical protein Y69H2.12 [Caenorhabditis elegans] ref|NP_507640.1| Y69H2.12 [Caenorhabditis elegans] 0.0
blast CAB63408 Hypothetical protein Y69H2.11 [Caenorhabditis elegans] ref|NP_507639.1| Y69H2.11 [Caenorhabditis elegans] 0.0
blast CAE73282 Hypothetical protein CBG20700 [Caenorhabditis briggsae] 0.0
blast CAB11570 Hypothetical protein Y69H2.2 [Caenorhabditis elegans] ref|NP_507638.1| Y69H2.2 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-9
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 5.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 4.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 2.5E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 6.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 6.6E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 7.3E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 3.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 5.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 4.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 2.5E-4
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 1.8E-40
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 9.7E-39
Pfam IPR008160 EMBL-EBI Collagen triple helix repeat 2.1E-4
Pfam IPR008160 EMBL-EBI Collagen triple helix repeat 2.6E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 6.6E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 7.3E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-9
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 5.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 4.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 2.5E-4
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 2.3E-37
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 2.1E-27
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000002596 1 2132-2154
Sequence
Target Sequence 
>C. ELEGANS:189370_AT
cctcggccagggaatctgcatcaacttgagcagtgacgtcacaaatggctatcaatgcat
ttgtgggccgctatggacagacacagactgcgagactccagtagcctctgcgtgtacccc
aagtccgtgctggaatgggatttgtgtgctcaatgagcagtataatacgtatacctgcgc
atgtgatgatggatatttcggggatctatgtcaataccccgacgtttgcacctcttccac
atgtctctacggcggtacttgcaccgagaccagcagtggagggtacacatgctcctgctt
gagccagtactttggcaccaactgtgaagagatcaatcgttgcaactatgcggatccatg
tgtgaatggtgactgccagactacggtagatgggatcactacaaactacacatgtacctg
cgatagtggatggaccggggagaattgtgatacaatgatcgactactgcatcccaaatcc
ctgctcttacaacagtacctgctctccgtacttcaaaggat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCTCGGCCAGGGAATCTGCATCAAC 43 267 987 Antisense
ATGCATTTGTGGGCCGCTATGGACA 352 41 1041 Antisense
CAGACTGCGAGACTCCAGTAGCCTC 204 205 1070 Antisense
AATACGTATACCTGCGCATGTGATG 194 173 1150 Antisense
GATCTATGTCAATACCCCGACGTTT 499 419 1189 Antisense
TCTACGGCGGTACTTGCACCGAGAC 195 579 1232 Antisense
TACACATGCTCCTGCTTGAGCCAGT 305 641 1270 Antisense
GAGCCAGTACTTTGGCACCAACTGT 283 385 1287 Antisense
GGTGACTGCCAGACTACGGTAGATG 456 489 1354 Antisense
AATCCCTGCTCTTACAACAGTACCT 47 169 1462 Antisense
ACCTGCTCTCCGTACTTCAAAGGAT 460 87 1483 Antisense
Sequence Source Affymetrix Proprietary Database