[Home] | [Total List]

[189364_at] glycohydrolase

Description H23L24.5 /REP_DB=WormBase Gene ID /WP=CE20978 /TR=Q9N5L4 /GB=AAF39896.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=glycohydrolase
Cluster 6grp_total > 12      4grp_total > 31      6grp_cgc > 33      6grp_cgc_sub > De      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 89
(3)
P 		9.9
(-2.8)
A 		6.8
(-3)
A 		68.6
(1.5)
A 		82
B 113.6
(3)
P 		4.3
(-3)
A 		5.9
(-2.9)
A 		9.8
(-2.7)
A 		109
C 82.5
(3)
P 		5.4
(-2.9)
A 		3.8
(-3)
A 		66.6
(1.8)
A 		79
avr 95
(3) 		6.5
(-2.9) 		5.5
(-3) 		48.3
(-0.1) 		90

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 128
1 2 3 4 5 6 range
A 106.7
(1.9)
P 		129.9
(3)
A 		95.2
(1.3)
A 		54.5
(-0.7)
A 		22.6
(-2.3)
A 		8.4
(-3)
A 		122
B 68.4
(0.8)
M 		106.6
(3)
P 		29.3
(-1.4)
A 		41.5
(-0.7)
A 		13.7
(-2.3)
A 		2.2
(-3)
A 		104
C 96.2
(1.9)
M 		117.3
(3)
P 		43.8
(-0.8)
A 		5.8
(-2.8)
A 		3.6
(-2.9)
A 		1.7
(-3)
A 		116
avr 90.4
(1.6) 		117.9
(3) 		56.1
(-0.3) 		33.9
(-1.4) 		13.3
(-2.5) 		4.1
(-3) 		114
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 35
1 2 3 4 range
A 32.4
(3)
P 		2.1
(-2.9)
A 		1.8
(-3)
A 		10
(-1.4)
A 		31
B 36.2
(3)
P 		1.1
(-3)
A 		1.4
(-2.9)
A 		2.1
(-2.8)
A 		35
C 27.3
(3)
P 		1.6
(-2.9)
A 		1.3
(-3)
A 		11.2
(-0.7)
A 		26
avr 32
(3) 		1.6
(-3) 		1.5
(-3) 		7.8
(-1.8) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 46
1 2 3 4 5 6 range
A 19.7
(-0.6)
P 		46.2
(3)
A 		20.7
(-0.5)
A 		13.8
(-1.4)
A 		6.8
(-2.4)
A 		2.1
(-3)
A 		44
B 23.8
(1)
M 		35.5
(3)
P 		7.1
(-1.9)
A 		11
(-1.2)
A 		5.6
(-2.2)
A 		0.8
(-3)
A 		35
C 35.6
(3)
M 		35.8
(3)
P 		11.1
(-1.2)
A 		1.2
(-2.9)
A 		1.2
(-2.9)
A 		0.6
(-3)
A 		35
avr 26.4
(1) 		39.2
(3) 		13
(-1.1) 		8.7
(-1.8) 		4.5
(-2.5) 		1.2
(-3) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189364_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8759
Sequence Type Exemplar sequence
Representative Public ID H23L24.5 NCBI
Target Description H23L24.5 /REP_DB=WormBase Gene ID /WP=CE20978 /TR=Q9N5L4 /GB=AAF39896.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=glycohydrolase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069095(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069095 NCBI Caenorhabditis elegans H23L24.5 (glycohydrolase) mRNA, complete cds. 11/11 None
SNAP00000025374 ENSEMBL cdna:SNAP chromosome:CEL140:IV:8712617:8715009:-1 11/11 None
GENEFINDER00000025378 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:8712617:8715009:-1 11/11 None
H23L24.5 ENSEMBL cdna:known chromosome:CEL140:IV:8712617:8715052:-1 gene:H23L24.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:8712622-8715015(-) 100.0 100.0
Public Domain and Genome References
Gene Title glycohydrolase
Gene Symbol pme-4
Ensembl H23L24.5
Entrez Gene 186765 Entrez gene
SwissProt Q9N5L4 EMBL-EBI
WormBase CE32685 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.11082.1.S1_AT similar to Poly(ADP-ribose) glycohydrolase cfa
DROSOPHILA_2:1640791_AT Poly(ADP-ribose) glycohydrolase dm
DROSGENOME1:154988_AT Poly(ADP-ribose) glycohydrolase dm
CHICKEN:GGAAFFX.1400.1.S1_AT similar to PARG protein gga
HG-U95AV2:337_AT poly (ADP-ribose) glycohydrolase hs
HC-G110:337_AT poly (ADP-ribose) glycohydrolase hs
HG-U133_PLUS_2:205060_AT poly (ADP-ribose) glycohydrolase hs
HG-U133A:205060_AT poly (ADP-ribose) glycohydrolase hs
HG-FOCUS:205060_AT poly (ADP-ribose) glycohydrolase hs
HG-U133A_2:205060_AT poly (ADP-ribose) glycohydrolase hs
HU35KSUBD:RC_R69293_AT poly (ADP-ribose) glycohydrolase hs
HUGENEFL:AF005043_AT poly (ADP-ribose) glycohydrolase hs
U133_X3P:G4505608_3P_X_AT poly (ADP-ribose) glycohydrolase hs
U133_X3P:G4505608_3P_AT poly (ADP-ribose) glycohydrolase hs
HG-U95AV2:38270_AT poly (ADP-ribose) glycohydrolase hs
HG-U95E:75836_S_AT poly (ADP-ribose) glycohydrolase hs
MOUSE430_2:1448725_AT poly (ADP-ribose) glycohydrolase mm
MOE430A:1448725_AT poly (ADP-ribose) glycohydrolase mm
MOUSE430A_2:1448725_AT poly (ADP-ribose) glycohydrolase mm
MU11KSUBA:AA162122_S_AT poly (ADP-ribose) glycohydrolase mm
MG-U74AV2:160949_AT poly (ADP-ribose) glycohydrolase mm
MU19KSUBA:TC21885_AT Poly (ADP-ribose) glycohydrolase (Parg), mRNA mm
RAE230A:1370354_AT poly (ADP-ribose) glycohydrolase rn
RAT230_2:1370354_AT poly (ADP-ribose) glycohydrolase rn
RG-U34B:RC_AI012311_AT poly (ADP-ribose) glycohydrolase rn
Protein Similarities
Method ID Description E-Value
blast AAF39896 Poly(adp-ribose) metabolism enzyme protein 4 [Caenorhabditis elegans] ref|NP_501496.2| H23L24.5 [Caenorhabditis elegans] gb|AAN40699.1| poly ADP-ribose metabolism enzyme 4 [Caenorhabditis elegans] sp|Q9N5L4|PME4_CAEEL Poly(ADP-ribose) glycohydrolase pme-4 (Poly ADP-ribose metabolism enzyme-4) 0.0
blast CAH60763 Hypothetical protein F20C5.1c [Caenorhabditis elegans] ref|NP_001023137.1| Poly(ADP-ribose) Metabolism Enzyme family member (pme-3) [Caenorhabditis elegans] 1.0E-142
blast CAA92299 Hypothetical protein F20C5.1b [Caenorhabditis elegans] ref|NP_001023136.1| Poly(ADP-ribose) Metabolism Enzyme family member (pme-3) [Caenorhabditis elegans] gb|AAO26317.1| poly ADP-ribose metabolism enzyme-3 short form [Caenorhabditis elegans] 1.0E-142
Protein Domains
Database ID Description E-Value
Pfam IPR007724 EMBL-EBI Poly glycohydrolase 1.0E-126
Pfam IPR007724 EMBL-EBI Poly glycohydrolase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:189364_AT
agcctatgttttcagttcctatactggatattctaacactctcaaatgggccaagataac
accaaagcactctgctcaaaataacaattcatttcgggatcaatttggacgtcttcaaac
tgaaacagttgcaattgatgctgttcgaaatgcggggacgccgttggaatgccttttaaa
tcaattaacaactgaaaaattaacacgagaagttcgaaaagctgcaattggatttttgag
tgccggtgacggattttcaaaaattccagttgtatcgggatggtggggatgtggagcatt
tcgaggaaataaaccattaaaattcctaattcaagtaattgcttgtggaatttctgatcg
accactacaattttgcacattcggagacactgaactggcaaaaaagtgcgaagaaatgat
gacgttattcagaaataacaatgtcagaacaggccaactatttttaattattaattccat
cgggccaccactcaactattctgaacag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGCCTATGTTTTCAGTTCCTATACT 99 77 921 Antisense
TACTGGATATTCTAACACTCTCAAA 433 647 942 Antisense
AGATAACACCAAAGCACTCTGCTCA 224 67 974 Antisense
TCGGGATCAATTTGGACGTCTTCAA 466 601 1014 Antisense
TGCTGTTCGAAATGCGGGGACGCCG 103 557 1059 Antisense
GACGCCGTTGGAATGCCTTTTAAAT 94 379 1077 Antisense
GGATTTTTGAGTGCCGGTGACGGAT 548 505 1150 Antisense
TGATCGACCACTACAATTTTGCACA 432 563 1275 Antisense
GCACATTCGGAGACACTGAACTGGC 673 315 1295 Antisense
AATTATTAATTCCATCGGGCCACCA 402 173 1386 Antisense
GCCACCACTCAACTATTCTGAACAG 650 279 1404 Antisense
Sequence Source Affymetrix Proprietary Database