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[189357_s_at] 7TM chemoreceptor, sri family /// 7TM chemoreceptor, sri family

Description Y27F2A.7 /REP_DB=WormBase Gene ID /WP=CE26058 /GEN=sri-34 /GB=AAK72091.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=chemoreceptor
Cluster 6grp_total > 43      4grp_total > 26      6grp_cgc > 80      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 0.8
(-2.7)
A 		7
(3)
A 		0.5
(-3)
A 		1.8
(-1.8)
A 		7
B 1.1
(-3)
A 		11.3
(3)
A 		2.9
(-1.9)
A 		1.6
(-2.7)
A 		10
C 1.3
(-3)
A 		12.9
(-0.9)
A 		6.8
(-2)
A 		33.9
(3)
A 		33
avr 1.1
(-3) 		10.4
(1.9) 		3.4
(-1.8) 		12.4
(3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6
1 2 3 4 5 6 range
A 4.5
(3)
A 		0.9
(-3)
A 		4.2
(2.5)
A 		1.5
(-2)
A 		1
(-2.8)
A 		0.9
(-3)
A 		4
B 2.1
(1.4)
A 		2.7
(3)
A 		1.1
(-1.2)
A 		0.4
(-3)
A 		0.7
(-2.2)
A 		2.3
(2)
A 		2
C 0.6
(-3)
A 		2.4
(-1)
A 		6.1
(3)
A 		0.7
(-2.9)
A 		1.1
(-2.5)
A 		0.7
(-2.9)
A 		6
avr 2.4
(0.1) 		2
(-0.7) 		3.8
(3) 		0.9
(-3) 		0.9
(-3) 		1.3
(-2.2) 		3
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6
1 2 3 4 range
A 0.3
(-2.1)
A 		1.5
(3)
A 		0.1
(-3)
A 		0.3
(-2.1)
A 		1
B 0.4
(-2.8)
A 		2.8
(3)
A 		0.7
(-2)
A 		0.3
(-3)
A 		3
C 0.4
(-3)
A 		3.7
(0.7)
A 		2.4
(-0.7)
A 		5.7
(3)
A 		5
avr 0.4
(-3) 		2.7
(3) 		1.1
(-1.2) 		2.1
(1.4) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2
1 2 3 4 5 6 range
A 0.8
(2.1)
A 		0.3
(-2.1)
A 		0.9
(3)
A 		0.4
(-1.3)
A 		0.3
(-2.1)
A 		0.2
(-3)
A 		1
B 0.7
(1.5)
A 		0.9
(3)
A 		0.3
(-1.5)
A 		0.1
(-3)
A 		0.3
(-1.5)
A 		0.8
(2.3)
A 		1
C 0.2
(-2.6)
A 		0.7
(-0.6)
A 		1.6
(3)
A 		0.1
(-3)
A 		0.3
(-2.2)
A 		0.2
(-2.6)
A 		2
avr 0.6
(0.4) 		0.6
(0.4) 		0.9
(3) 		0.2
(-3) 		0.3
(-2.1) 		0.4
(-1.3) 		1
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189357_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4136
Sequence Type Exemplar sequence
Representative Public ID Y27F2A.7 NCBI
Target Description Y27F2A.7 /REP_DB=WormBase Gene ID /WP=CE26058 /GEN=sri-34 /GB=AAK72091.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=chemoreceptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062061(11), NM_062062(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062061 NCBI Caenorhabditis elegans Serpentine Receptor, class I family member (sri-33) (sri-33) mRNA, complete cds. 11/11 A 
NM_062062 NCBI Caenorhabditis elegans Serpentine Receptor, class I family member (sri-34) (sri-34) mRNA, complete cds. 11/11 A 
GENEFINDER00000006781 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:3154553:3156377:-1 11/11 None
Y27F2A.4 ENSEMBL cdna:known chromosome:CEL140:II:3155162:3156844:-1 gene:Y27F2A.4 11/11 A 
Y27F2A.7 ENSEMBL cdna:known chromosome:CEL140:II:3157486:3159080:-1 gene:Y27F2A.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000006762 8/11 Cross Hyb Matching Probes None
GENEFINDER00000006779 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:3157484-3159079(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, sri family
7TM chemoreceptor, sri family
Gene Symbol sri-33
sri-34
Ensembl Y27F2A.4
Y27F2A.7
Entrez Gene 191908 Entrez gene
191909 Entrez gene
SwissProt Q966C4 EMBL-EBI
Q966C3 EMBL-EBI
WormBase CE26056 Wormbase
CE26058 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_494462 Serpentine Receptor, class I family member (sri-33) [Caenorhabditis elegans] gb|AAK72090.1| Serpentine receptor, class i protein 33 [Caenorhabditis elegans] 1.0E-174
blast NP_494463 Serpentine Receptor, class I family member (sri-34) [Caenorhabditis elegans] gb|AAK72091.1| Serpentine receptor, class i protein 34 [Caenorhabditis elegans] 1.0E-173
blast NP_494462 Serpentine Receptor, class I family member (sri-33) [Caenorhabditis elegans] gb|AAK72090.1| Serpentine receptor, class i protein 33 [Caenorhabditis elegans] 1.0E-138
blast NP_494463 Serpentine Receptor, class I family member (sri-34) [Caenorhabditis elegans] gb|AAK72091.1| Serpentine receptor, class i protein 34 [Caenorhabditis elegans] 1.0E-136
blast NP_494462 Serpentine Receptor, class I family member (sri-33) [Caenorhabditis elegans] gb|AAK72090.1| Serpentine receptor, class i protein 33 [Caenorhabditis elegans] 1.0E-129
blast NP_494463 Serpentine Receptor, class I family member (sri-34) [Caenorhabditis elegans] gb|AAK72091.1| Serpentine receptor, class i protein 34 [Caenorhabditis elegans] 1.0E-112
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 3.0E-31
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.8E-47
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 2.6E-47
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_494462.1 7 10-32,45-64,92-114,134-156,186-208,240-262,277-299
NP_494463.1 7 10-32,45-64,92-114,134-156,189-211,242-264,279-301
Y27F2A.4 7 10-32,45-64,92-114,134-156,186-208,240-262,277-299
Y27F2A.7 7 10-32,45-64,92-114,134-156,189-211,242-264,279-301
GENEFINDER00000006781 6 13-35,53-75,95-117,147-169,200-222,242-264
Sequence
Target Sequence 
>C. ELEGANS:189357_S_AT
ttcaagcatcaggcgattgcacaagttttgaacaagcatgttgtatcgaaaaagatacga
cttctacgtaaaagttcctatgttttcgtccccggctccgcatttttgacattcttgcaa
ggaagtaccagaagagaggatcagctgaaatttattgaatctcgatatccaaaatatcta
tctgaattcaaaaatctctccaactttgcaatataccagttcaacatttggcatgttttt
ctagcaattgttggggttatcggagggatgttctgcgcaataactggagtttatactaca
gtagatattttcaaaatgttacaagaggtgcagacaaaagtgtctagttcaagctttcaa
cgctatcaatctgcaattcgtagtttggtatctcaaatgtttgcttctttgatgctattt
gttccgttgttcatttttgtgatgcttataaccggtgtggataatgggcaatttattgga
gaacttctgcaatcaatttgtgcgttgcaatctattgtgaacgcggtggtgttaatattc
acaacgccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCAAGCATCAGGCGATTGCACAAG 439 685 352 Antisense
GCGATTGCACAAGTTTTGAACAAGC 25 291 364 Antisense
CGACTTCTACGTAAAAGTTCCTATG 74 253 409 Antisense
GGCTCCGCATTTTTGACATTCTTGC 589 539 445 Antisense
GACATTCTTGCAAGGAAGTACCAGA 498 369 459 Antisense
AATTTATTGAATCTCGATATCCAAA 370 175 500 Antisense
ATATCCAAAATATCTATCTGAATTC 421 21 516 Antisense
AATCTCTCCAACTTTGCAATATACC 685 169 544 Antisense
ATCAATTTGTGCGTTGCAATCTATT 224 27 843 Antisense
GCAATCTATTGTGAACGCGGTGGTG 218 321 858 Antisense
GGTGGTGTTAATATTCACAACGCCC 512 499 876 Antisense
Sequence Source Affymetrix Proprietary Database