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[189337_at] protein kinase

Description F40G9.13 /REP_DB=WormBase Gene ID /WP=CE19860 /TR=Q9TZ80 /GB=AAC68802.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 01      4grp_total > 41      6grp_cgc > 63      6grp_cgc_sub > 02      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 70
1 2 3 4 range
A 44.3
(-3)
M 		70.3
(0)
A 		95.6
(3)
P 		45.1
(-2.9)
A 		51
B 26.1
(-3)
A 		71.8
(1.5)
A 		87.1
(3)
A 		64.6
(0.8)
P 		61
C 60.4
(-2.2)
A 		91.2
(3)
A 		62.8
(-1.8)
A 		55.5
(-3)
P 		36
avr 43.6
(-3) 		77.8
(2.4) 		81.8
(3) 		55.1
(-1.2) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 72
1 2 3 4 5 6 range
A 25.1
(-3)
A 		45.7
(-0.3)
A 		30.8
(-2.3)
A 		31
(-2.2)
A 		71
(3)
A 		28.7
(-2.5)
A 		46
B 89.6
(3)
P 		47.1
(-0.5)
P 		17.9
(-3)
A 		48.6
(-0.4)
P 		17.6
(-3)
A 		38.5
(-1.3)
P 		72
C 21.1
(-3)
P 		86
(2.8)
M 		75.5
(1.9)
A 		87.8
(3)
M 		33.4
(-1.9)
P 		69.3
(1.3)
P 		67
avr 45.3
(-1.5) 		59.6
(3) 		41.4
(-2.8) 		55.8
(1.8) 		40.7
(-3) 		45.5
(-1.5) 		19
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 16.1
(0.1)
M 		15.3
(-0.2)
A 		25
(3)
P 		6.6
(-3)
A 		18
B 8.3
(-3)
A 		17.7
(1.7)
A 		20.2
(3)
A 		13.8
(-0.2)
P 		12
C 20
(0.8)
A 		26.2
(3)
A 		21.9
(1.5)
A 		9.4
(-3)
P 		17
avr 14.8
(-0.6) 		19.7
(1.7) 		22.4
(3) 		9.9
(-3) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27
1 2 3 4 5 6 range
A 4.6
(-3)
A 		16.2
(1.1)
A 		6.7
(-2.3)
A 		7.9
(-1.8)
A 		21.4
(3)
A 		7
(-2.1)
A 		17
B 31.2
(3)
P 		15.7
(-0.5)
P 		4.3
(-3)
A 		12.9
(-1.1)
P 		7.1
(-2.4)
A 		14.4
(-0.7)
P 		27
C 7.8
(-3)
P 		26.2
(3)
M 		19.2
(0.7)
A 		17.7
(0.2)
M 		10.8
(-2)
P 		23.2
(2)
P 		18
avr 14.5
(-0.2) 		19.4
(3) 		10.1
(-3) 		12.8
(-1.3) 		13.1
(-1.1) 		14.9
(0.1) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189337_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8312
Sequence Type Exemplar sequence
Representative Public ID F40G9.13 NCBI
Target Description F40G9.13 /REP_DB=WormBase Gene ID /WP=CE19860 /TR=Q9TZ80 /GB=AAC68802.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064761(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064761 NCBI Caenorhabditis elegans VEGF (vascular endothelial growth factor) Receptor family member (ver-1) (ver-1) mRNA, complete cds. 11/11 A 
SNAP00000021763 ENSEMBL cdna:SNAP chromosome:CEL140:III:162148:163541:1 11/11 None
T17A3.1 ENSEMBL cdna:known chromosome:CEL140:III:156823:163541:1 gene:T17A3.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000021790 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:162147-163541(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Gene Symbol ver-1
Ensembl T17A3.1
Entrez Gene 175182 Entrez gene
SwissProt O76698 EMBL-EBI
WormBase CE31854 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC26948 Vegf (vascular endothelial growth factor) receptor family protein 1 [Caenorhabditis elegans] ref|NP_497162.2| VEGF (vascular endothelial growth factor) Receptor family member (ver-1) [Caenorhabditis elegans] gb|AAF00548.1| tyrosine kinase receptor T17A3.1 [Caenorhabditis elegans] 0.0
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 0.0
blast CAE70781 Hypothetical protein CBG17536 [Caenorhabditis briggsae] 0.0
blast AAC26948 Vegf (vascular endothelial growth factor) receptor family protein 1 [Caenorhabditis elegans] ref|NP_497162.2| VEGF (vascular endothelial growth factor) Receptor family member (ver-1) [Caenorhabditis elegans] gb|AAF00548.1| tyrosine kinase receptor T17A3.1 [Caenorhabditis elegans] 1.0E-118
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 8.0E-55
blast CAA91991 Hypothetical protein F59F3.5 [Caenorhabditis elegans] ref|NP_509835.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-4) [Caenorhabditis elegans] 6.0E-53
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-53
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.01
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 8.2E-5
Pfam IPR000719 EMBL-EBI Protein kinase 5.5E-30
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497162.2 2 13-35,736-758
T17A3.1 2 13-35,736-758
Sequence
Target Sequence 
>C. ELEGANS:189337_AT
gaggtaacctacgagatttcttgcaacaacggaggaatgtgttcattgatgagcttcatg
ataactttgatgagaatattccattgatccggccggatttcaattcgctatccaccactg
acctggtgggaatagcacatcagattgcgaatgggatggagtggcttggaaatgttccgt
gtgttcatgggaatttgtgttgccgtaaggtgctgatctcaaaaacgaaaacgattcgga
taacggactacggagttggagataggcaacgaaaatcctcctcgatgagatggatggcac
cggaagccatcgaacatcagatgttctcctcaaaatctgatgtctggtcatttggcatct
gcctctacgaaatcttcactttgggtgggaccccgtacccaacttgcgttacagagaaca
tcctgaaacatattaaaaatggaagtcggaatttgcaaccggaatactgtcctagcgcac
tgtatgatcttatgcagttgtgctggcgagctccacctcaggaccgaccgaaattttccc
tgtgctcgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGGTAACCTACGAGATTTCTTGCA 354 403 29 Antisense
GCCGGATTTCAATTCGCTATCCACC 43 283 120 Antisense
GTGTTGCCGTAAGGTGCTGATCTCA 9 377 225 Antisense
GGCAACGAAAATCCTCCTCGATGAG 461 533 293 Antisense
GGCACCGGAAGCCATCGAACATCAG 607 535 324 Antisense
CTGCCTCTACGAAATCTTCACTTTG 275 237 387 Antisense
CCGTACCCAACTTGCGTTACAGAGA 134 265 421 Antisense
GCAACCGGAATACTGTCCTAGCGCA 46 321 483 Antisense
GTCCTAGCGCACTGTATGATCTTAT 69 477 497 Antisense
TTATGCAGTTGTGCTGGCGAGCTCC 313 679 518 Antisense
CGACCGAAATTTTCCCTGTGCTCGG 526 249 553 Antisense
Sequence Source Affymetrix Proprietary Database