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[189329_s_at] aldose reductase

Description ZC443.1 /REP_DB=WormBase Gene ID /WP=CE27788 /TR=Q23320 /GB=CAA99947.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=aldose reductase
Cluster 6grp_highest_10_10 > 35      6grp_high1_10_10 > 53      4grp_highest_8_8 > 07      4grp_high_8_8 > 29      6grp_highest_nonorm > 81      6grp_total > 52      4grp_total > 27      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 301
1 2 3 4 range
A 216.6
(-2.6)
P 		380.9
(2.4)
P 		203
(-3)
P 		400.4
(3)
P 		197
B 202.5
(-2.9)
P 		333.7
(-0.3)
P 		198.4
(-3)
P 		499.4
(3)
P 		301
C 294.2
(-0.7)
P 		376
(2.2)
P 		231.4
(-3)
P 		398
(3)
P 		167
avr 237.8
(-2.3) 		363.5
(1.1) 		210.9
(-3) 		432.6
(3) 		222

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 245
1 2 3 4 5 6 range
A 187
(-2.5)
P 		176
(-3)
P 		307.6
(2.4)
P 		268.4
(0.8)
P 		253.6
(0.2)
P 		321
(3)
P 		145
B 255.8
(-0.4)
P 		340.2
(2.5)
P 		356.6
(3)
P 		265.7
(-0)
P 		196
(-2.4)
P 		176.7
(-3)
P 		180
C 253
(-0.4)
P 		382.8
(2.8)
P 		389.7
(3)
P 		264.4
(-0.1)
P 		151.1
(-2.8)
P 		144.9
(-3)
P 		245
avr 231.9
(-1.7) 		299.7
(1) 		351.3
(3) 		266.2
(-0.4) 		200.2
(-3) 		214.2
(-2.4) 		151
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 62
1 2 3 4 range
A 78.8
(2.2)
P 		82.7
(3)
P 		53.1
(-3)
P 		58.6
(-1.9)
P 		30
B 64.6
(-1.2)
P 		82.4
(0.6)
P 		46
(-3)
P 		106.4
(3)
P 		60
C 97.4
(1.4)
P 		108.1
(3)
P 		80.7
(-1)
P 		67.1
(-3)
P 		41
avr 80.3
(0.9) 		91.1
(3) 		59.9
(-3) 		77.4
(0.4) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 82
1 2 3 4 5 6 range
A 34.5
(-3)
P 		62.6
(0.9)
P 		67
(1.5)
P 		68.1
(1.6)
P 		76.5
(2.8)
P 		78.2
(3)
P 		44
B 89
(-0.1)
P 		113.2
(3)
P 		86.6
(-0.4)
P 		70.4
(-2.4)
P 		79.6
(-1.3)
P 		65.9
(-3)
P 		47
C 93.8
(1)
P 		116.8
(3)
P 		99.2
(1.5)
P 		53.2
(-2.6)
P 		48.9
(-3)
P 		48.5
(-3)
P 		68
avr 72.4
(-1.5) 		97.5
(3) 		84.3
(0.6) 		63.9
(-3) 		68.3
(-2.2) 		64.2
(-2.9) 		34
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189329_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14665
Sequence Type Exemplar sequence
Representative Public ID ZC443.1 NCBI
Target Description ZC443.1 /REP_DB=WormBase Gene ID /WP=CE27788 /TR=Q23320 /GB=CAA99947.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=aldose reductase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073804(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073804 NCBI Caenorhabditis elegans ZC443.1 (ZC443.1) mRNA, complete cds. 11/11 A 
SNAP00000030942 ENSEMBL cdna:SNAP chromosome:CEL140:V:12811083:12812648:-1 11/11 None
GENEFINDER00000030950 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12811083:12812179:-1 11/11 None
ZC443.1 ENSEMBL cdna:known chromosome:CEL140:V:12811073:12812661:-1 gene:ZC443.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12811060-12812648(-) 100.0 100.0
Public Domain and Genome References
Gene Title aldose reductase
Ensembl ZC443.1
Entrez Gene 179756 Entrez gene
SwissProt Q23320 EMBL-EBI
WormBase CE27788 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1640451_AT dm
DROSGENOME1:142257_AT dm
Protein Similarities
Method ID Description E-Value
blast CAA99947 Hypothetical protein ZC443.1 [Caenorhabditis elegans] ref|NP_506205.1| ZC443.1 [Caenorhabditis elegans] 0.0
blast CAA99947 Hypothetical protein ZC443.1 [Caenorhabditis elegans] ref|NP_506205.1| ZC443.1 [Caenorhabditis elegans] 1.0E-168
blast CAE64002 Hypothetical protein CBG08596 [Caenorhabditis briggsae] 1.0E-157
blast CAE64002 Hypothetical protein CBG08596 [Caenorhabditis briggsae] 1.0E-144
blast CAE65877 Hypothetical protein CBG11027 [Caenorhabditis briggsae] 3.0E-85
Protein Domains
Database ID Description E-Value
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 1.0E-126
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 5.2E-115
Sequence
Target Sequence 
>C. ELEGANS:189329_S_AT
gacaaacatgtgaaggcgctcgcacagaaatacagtaaaactccagctcagattcttctc
cgggctacagttgaaatgggaattatagttattccaaaaactacgaatcctgaaagaatg
aaagaaaacatcaacatttttgatttcaacatttcaaatgctgaagtaaatctcctagaa
gcgcacgagagaacaaaacaggaaagacttttctggtggccaaagtatttttttttaagc
aacaaaaatgatactgaacactatttttcagcgttgctgatcatcctgaagatccattcg
cgacac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACAAACATGTGAAGGCGCTCGCAC 126 367 709 Antisense
GAAGGCGCTCGCACAGAAATACAGT 320 333 720 Antisense
GAAATACAGTAAAACTCCAGCTCAG 498 361 735 Antisense
TAAAACTCCAGCTCAGATTCTTCTC 118 641 744 Antisense
ATTCTTCTCCGGGCTACAGTTGAAA 316 9 760 Antisense
CCGGGCTACAGTTGAAATGGGAATT 417 229 768 Antisense
TCCAAAAACTACGAATCCTGAAAGA 695 585 801 Antisense
CAAATGCTGAAGTAAATCTCCTAGA 579 193 863 Antisense
AAGTAAATCTCCTAGAAGCGCACGA 437 157 872 Antisense
GAAGCGCACGAGAGAACAAAACAGG 457 343 886 Antisense
CATCCTGAAGATCCATTCGCGACAC 418 209 990 Antisense
Sequence Source Affymetrix Proprietary Database