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[189318_at] GNS1/SUR4 family

Description F11E6.5 /REP_DB=WormBase Gene ID /WP=CE19785 /TR=Q9XVQ9 /GB=CAB02921.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=GNS1-SUR4 family
Cluster 6grp_highest_10_10 > 04      6grp_high1_10_10 > 21      4grp_highest_8_8 > 18      4grp_high_8_8 > 62      6grp_highest_nonorm > 15      6grp_total > 32      4grp_total > 56      6grp_cgc > 61      6grp_high1_sub > 03      6grp_cgc_sub > De      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2448
1 2 3 4 range
A 5969.8
(1.1)
P 		5539.7
(-0.3)
P 		6571.3
(3)
P 		4676.1
(-3)
P 		1895
B 5445.5
(-2.2)
P 		5615.1
(-1.5)
P 		6613
(3)
P 		5269.2
(-3)
P 		1344
C 4927.3
(-1.7)
P 		6364.9
(1.8)
P 		6864.3
(3)
P 		4416.5
(-3)
P 		2448
avr 5447.5
(-0.9) 		5839.9
(0.3) 		6682.9
(3) 		4787.3
(-3) 		1896

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 5792
1 2 3 4 5 6 range
A 6574.7
(3)
P 		6403.8
(2.7)
P 		6222
(2.5)
P 		5790.6
(1.8)
P 		3955.2
(-1.1)
P 		2696.9
(-3)
P 		3878
B 5777.5
(1.8)
P 		6590
(3)
P 		5513.2
(1.5)
P 		5212.7
(1)
P 		4137.4
(-0.5)
P 		2355.8
(-3)
P 		4234
C 5662.3
(0.4)
P 		6336.8
(1.1)
P 		8147.8
(3)
P 		5706.1
(0.4)
P 		4090
(-1.3)
P 		2430.6
(-3)
P 		5717
avr 6004.8
(2.1) 		6443.5
(2.7) 		6627.7
(3) 		5569.8
(1.5) 		4060.9
(-0.7) 		2494.4
(-3) 		4133
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1708
1 2 3 4 range
A 2173.6
(3)
P 		1202.5
(-0.9)
P 		1717.9
(1.2)
P 		684.5
(-3)
P 		1489
B 1736.5
(3)
P 		1386.8
(-0.4)
P 		1532.4
(1)
P 		1122.9
(-3)
P 		614
C 1631.1
(0.2)
P 		1830
(1)
P 		2392.4
(3)
P 		744.7
(-3)
P 		1648
avr 1847.1
(2.8) 		1473.1
(0.6) 		1880.9
(3) 		850.7
(-3) 		1030

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1621
1 2 3 4 5 6 range
A 1212
(-0.9)
P 		2277.5
(3)
P 		1355
(-0.4)
P 		1468.6
(0)
P 		1193.5
(-1)
P 		656.6
(-3)
P 		1621
B 2010.3
(2.2)
P 		2193.5
(3)
P 		1338.8
(-0.9)
P 		1380.7
(-0.7)
P 		1681
(0.7)
P 		878.5
(-3)
P 		1315
C 2098.8
(3)
P 		1933.5
(2.2)
P 		2073.8
(2.9)
P 		1147.5
(-1.4)
P 		1323.5
(-0.6)
P 		813.7
(-3)
P 		1285
avr 1773.7
(1.4) 		2134.8
(3) 		1589.2
(0.6) 		1332.3
(-0.6) 		1399.3
(-0.3) 		782.9
(-3) 		1352
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189318_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9305
Sequence Type Exemplar sequence
Representative Public ID F11E6.5 NCBI
Target Description F11E6.5 /REP_DB=WormBase Gene ID /WP=CE19785 /TR=Q9XVQ9 /GB=CAB02921.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=GNS1-SUR4 family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070713(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070713 NCBI Caenorhabditis elegans fatty acid ELOngation family member (elo-2) (elo-2) mRNA, complete cds. 11/11 None
SNAP00000042534 ENSEMBL cdna:SNAP chromosome:CEL140:IV:17466220:17467354:-1 11/11 None
GENEFINDER00000042541 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:17466220:17467354:-1 11/11 None
F11E6.5.1 ENSEMBL cdna:known chromosome:CEL140:IV:17466017:17467363:-1 gene:F11E6.5 11/11 None
F11E6.5.2 ENSEMBL cdna:known chromosome:CEL140:IV:17466017:17467373:-1 gene:F11E6.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:17466225-17467360(-) 100.0 100.0
Public Domain and Genome References
Gene Title GNS1/SUR4 family
Gene Symbol elo-2
Ensembl F11E6.5
Entrez Gene 178532 Entrez gene
SwissProt Q9XVQ9 EMBL-EBI
WormBase CE19785 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CHICKEN:GGAAFFX.3516.1.S1_AT similar to ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); long-chain fatty-acyl elongase gga
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02921 Hypothetical protein F11E6.5 [Caenorhabditis elegans] ref|NP_503114.1| fatty acid ELOngation family member (elo-2) [Caenorhabditis elegans] 1.0E-159
blast CAE57472 Hypothetical protein CBG00438 [Caenorhabditis briggsae] 1.0E-149
Protein Domains
Database ID Description E-Value
Pfam IPR002076 EMBL-EBI GNS1/SUR4 membrane protein 5.3E-45
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_503114.1 5 28-50,71-93,165-187,199-221,236-258
F11E6.5.1 5 28-50,71-93,165-187,199-221,236-258
F11E6.5.2 5 28-50,71-93,165-187,199-221,236-258
SNAP00000042534 5 28-50,71-93,165-187,199-221,236-258
GENEFINDER00000042541 5 28-50,71-93,165-187,199-221,236-258
Sequence
Target Sequence 
>C. ELEGANS:189318_AT
tgctctctggaacttcgggttttcactgttctcgggaatcgccgcctataagcttattcc
agaactattcggagttttcatgaaggacgggtttgtcgcttcctactgtcaaaacgagaa
ctactacaccgatgcatcaactggattctggggctgggcctttgtgatgtcgaaagctcc
agaactaggggatactatgttcttggtccttcgtaaaaaaccagttatcttcatgcactg
gtatcatcatgccctcacatttgtctacgcagtagtcacatactctgagcatcaggcatg
ggctcgttggtctttggctctcaaccttgccgtccacactgttatgtatttctacttcgc
cgttcgcgccttgaacatccaaactccacgcccagtggcaaagttcatcactactattca
aattgtccaatttgtcatctcatgctacatttttgggcatttggtattcattaagtctgc
tgattctgttcctggttgcgctgttagctggaatgtgctatcgatcggaggactcatgta
catcagttatttgttcctttttgccaagttcttcta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCTCTCTGGAACTTCGGGTTTTCA 136 577 210 Antisense
TTTCACTGTTCTCGGGAATCGCCGC 684 671 230 Antisense
GAATCGCCGCCTATAAGCTTATTCC 663 329 245 Antisense
TGAAGGACGGGTTTGTCGCTTCCTA 303 571 290 Antisense
GAACTACTACACCGATGCATCAACT 431 349 327 Antisense
CATCAACTGGATTCTGGGGCTGGGC 359 213 344 Antisense
GGGATACTATGTTCTTGGTCCTTCG 633 493 398 Antisense
TGCCGTCCACACTGTTATGTATTTC 555 585 537 Antisense
CAAACTCCACGCCCAGTGGCAAAGT 231 189 589 Antisense
ATTAAGTCTGCTGATTCTGTTCCTG 666 11 679 Antisense
TGTTCCTTTTTGCCAAGTTCTTCTA 453 561 761 Antisense
Sequence Source Affymetrix Proprietary Database