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[189312_at] protein kinase

Description R06A10.4 /REP_DB=WormBase Gene ID /WP=CE12518 /TR=O44747 /GB=AAB96730.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 29      4grp_total > 29      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 166
1 2 3 4 range
A 198.7
(0.4)
P 		188
(-0.1)
A 		125.2
(-3)
A 		253.9
(3)
A 		129
B 180.3
(1.9)
P 		185.4
(2.1)
A 		88.1
(-3)
A 		201.7
(3)
P 		114
C 243.9
(3)
P 		156.7
(-2)
A 		139.6
(-3)
A 		187.8
(-0.2)
A 		104
avr 207.6
(2.6) 		176.7
(0.7) 		117.6
(-3) 		214.5
(3) 		97

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 203
1 2 3 4 5 6 range
A 184.2
(2)
P 		205.2
(3)
P 		84.8
(-3)
A 		109.9
(-1.7)
P 		165.2
(1)
P 		161.5
(0.8)
P 		120
B 201.9
(3)
P 		166
(1.2)
P 		90.4
(-2.5)
A 		80.1
(-3)
A 		146.1
(0.3)
A 		136.7
(-0.2)
P 		122
C 282.3
(3)
P 		121.3
(-1.8)
P 		159.4
(-0.6)
M 		79.8
(-3)
A 		265.4
(2.5)
P 		134.9
(-1.4)
P 		203
avr 222.8
(3) 		164.2
(0.4) 		111.5
(-2) 		89.9
(-3) 		192.2
(1.6) 		144.4
(-0.5) 		133
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 72.4
(3)
P 		40.8
(-1.8)
A 		32.7
(-3)
A 		37.2
(-2.3)
A 		40
B 57.5
(3)
P 		45.8
(1.1)
A 		20.4
(-3)
A 		43
(0.7)
P 		37
C 80.7
(3)
P 		45
(-1.4)
A 		48.7
(-0.9)
A 		31.7
(-3)
A 		49
avr 70.2
(3) 		43.9
(-1.3) 		33.9
(-3) 		37.3
(-2.4) 		36

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 89
1 2 3 4 5 6 range
A 34
(-1.3)
P 		73
(3)
P 		18.5
(-3)
A 		27.9
(-2)
P 		49.9
(0.5)
P 		39.3
(-0.7)
P 		55
B 70.3
(3)
P 		55.2
(1.2)
P 		22
(-2.9)
A 		21.2
(-3)
A 		59.4
(1.7)
A 		51
(0.6)
P 		49
C 104.6
(3)
P 		37
(-1.6)
P 		40.6
(-1.3)
M 		16.1
(-3)
A 		85.9
(1.7)
P 		45.1
(-1)
P 		89
avr 69.6
(3) 		55.1
(1.2) 		27
(-2.3) 		21.7
(-3) 		65.1
(2.4) 		45.1
(-0.1) 		48
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189312_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.37
Sequence Type Exemplar sequence
Representative Public ID R06A10.4 NCBI
Target Description R06A10.4 /REP_DB=WormBase Gene ID /WP=CE12518 /TR=O44747 /GB=AAB96730.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058419(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058419 NCBI Caenorhabditis elegans R06A10.4 (R06A10.4) mRNA, complete cds. 11/11 None
SNAP00000037729 ENSEMBL cdna:SNAP chromosome:CEL140:I:1087127:1095795:-1 11/11 None
GENEFINDER00000037731 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:1089742:1095795:-1 11/11 None
R06A10.4 ENSEMBL cdna:known chromosome:CEL140:I:1089668:1095798:-1 gene:R06A10.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1090069-1095795(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl R06A10.4
Entrez Gene 171688 Entrez gene
SwissProt O44747 EMBL-EBI
WormBase CE12518 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17058_S_AT calcium-dependent protein kinase, putative / CDPK, putative at
ATH1-121501:254224_AT calcium-dependent protein kinase, putative / CDPK, putative at
CHICKEN:GGA.11718.1.S1_AT protein serine kinase H1 gga
U133_X3P:HS.150601.1.A1_3P_AT protein serine kinase H1 hs
HG-U95AV2:40206_AT protein serine kinase H1 hs
HG-U95AV2:40207_G_AT protein serine kinase H1 hs
HG-U95D:81081_AT protein serine kinase H1 hs
HG-U95D:84760_R_AT protein serine kinase H1 hs
HG-U133A_2:213141_AT Protein serine kinase H1 hs
HG-U133_PLUS_2:213141_AT Protein serine kinase H1 hs
HG-U133A:213141_AT Protein serine kinase H1 hs
HG-U95E:73710_AT Protein serine kinase H1 hs
MG-U74BV2:163308_AT protein serine kinase H1 mm
MOE430B:1433522_AT protein serine kinase H1 mm
MOUSE430_2:1433522_AT protein serine kinase H1 mm
MOE430B:1447672_X_AT protein serine kinase H1 mm
MOUSE430_2:1447672_X_AT protein serine kinase H1 mm
MOUSE430_2:1419847_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MOUSE430A_2:1419847_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MOE430A:1419847_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MOE430B:1445018_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MOUSE430_2:1445018_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MG-U74AV2:95372_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MU11KSUBA:AA217469_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
MU19KSUBA:TC18373_AT Protein serine kinase H1, mRNA (cDNA clone MGC:60799 IMAGE:30024345) mm
RG-U34B:RC_AI013362_AT protein serine kinase H1 (predicted) rn
RG-U34B:RC_AI058755_AT protein serine kinase H1 (predicted) rn
RAE230A:1390288_AT protein serine kinase H1 (predicted) rn
RAT230_2:1390288_AT protein serine kinase H1 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB96730 Hypothetical protein R06A10.4 [Caenorhabditis elegans] ref|NP_490820.1| R06A10.4 [Caenorhabditis elegans] 0.0
blast CAE74364 Hypothetical protein CBG22088 [Caenorhabditis briggsae] 0.0
blast AAX19940 protein serine kinase [Pinctada fucata] 1.0E-75
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-60
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-60
hanks 2.1.8 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DdMLCK 2.0E-73
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.5E-78
Sequence
Target Sequence 
>C. ELEGANS:189312_AT
cacgtctccttatcacagatttcggtctagcatatcaggccaccaaaccgaatgagacaa
tgacagaaacctgcggaacaccagagtatattgctccagagcttctgttaagagtaccct
atactcagaaggtggatatgtgggcggtgggtgtaattgcctatatcctaatgtccggaa
ttatgccgttcgatgatgattgtcgaagtcgcctctacacacatattattacggcgaact
atgtatattatccacagttctggtcgggatccgagttggccaaacagttcgtcgactccc
tcctcgaaaccaattcagtggagcgcctcagctcatcggcggccatgaaacacgagtggc
tcaccggagagcggccctcgacgacgcagagcaggccgccgaccaggcctacgtcagagt
ataatagcatgcaaaggaccaaatctactcgttcaatacgatcggtcacacgatccgatc
acggacatcgcgtggatccacgtg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACGTCTCCTTATCACAGATTTCGG 626 199 617 Antisense
TTCGGTCTAGCATATCAGGCCACCA 166 693 637 Antisense
GTGGGTGTAATTGCCTATATCCTAA 228 487 763 Antisense
GATGATTGTCGAAGTCGCCTCTACA 192 411 811 Antisense
CCACAGTTCTGGTCGGGATCCGAGT 290 275 868 Antisense
AGTTGGCCAAACAGTTCGTCGACTC 387 61 890 Antisense
AATTCAGTGGAGCGCCTCAGCTCAT 431 175 928 Antisense
CCGACCAGGCCTACGTCAGAGTATA 710 257 1015 Antisense
GGACCAAATCTACTCGTTCAATACG 156 523 1052 Antisense
TCGGTCACACGATCCGATCACGGAC 304 605 1078 Antisense
CACGGACATCGCGTGGATCCACGTG 440 199 1096 Antisense
Sequence Source Affymetrix Proprietary Database