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[189290_at] protein kinase

Description K11H12.9 /REP_DB=WormBase Gene ID /WP=CE12162 /TR=P91376 /GB=AAC24403.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 03      4grp_total > 28      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 162
1 2 3 4 range
A 150
(3)
P 		112.4
(1.2)
A 		21.9
(-3)
A 		134
(2.3)
A 		128
B 126.1
(-1.3)
M 		144
(0)
A 		103.6
(-3)
A 		184
(3)
A 		80
C 107.1
(1)
P 		127.2
(3)
A 		67.8
(-3)
A 		119.3
(2.2)
A 		59
avr 127.7
(1.7) 		127.9
(1.7) 		64.4
(-3) 		145.8
(3) 		81

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 168
1 2 3 4 5 6 range
A 183.7
(3)
A 		139.8
(1.4)
A 		22.2
(-2.8)
A 		43.8
(-2)
A 		80.9
(-0.7)
A 		17.3
(-3)
A 		166
B 139.3
(3)
A 		120.8
(2.1)
A 		69.1
(-0.4)
A 		100.7
(1.1)
A 		15.4
(-3)
A 		47.2
(-1.5)
A 		124
C 89.8
(-0.1)
A 		109.1
(3)
A 		77.9
(-2.1)
A 		87.3
(-0.5)
P 		94
(0.5)
A 		72.2
(-3)
A 		37
avr 137.6
(3) 		123.2
(2.1) 		56.4
(-2.3) 		77.3
(-0.9) 		63.4
(-1.8) 		45.6
(-3) 		92
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 49
1 2 3 4 range
A 54.6
(3)
P 		24.4
(-0.7)
A 		5.7
(-3)
A 		19.6
(-1.3)
A 		49
B 40.2
(3)
M 		35.6
(1.3)
A 		24
(-3)
A 		39.2
(2.6)
A 		16
C 35.5
(2.6)
P 		36.6
(3)
A 		23.6
(-1.7)
A 		20.1
(-3)
A 		17
avr 43.4
(3) 		32.2
(0.4) 		17.8
(-3) 		26.3
(-1) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 46
1 2 3 4 5 6 range
A 33.9
(0.9)
A 		49.7
(3)
A 		4.8
(-2.9)
A 		11.1
(-2.1)
A 		24.4
(-0.3)
A 		4.2
(-3)
A 		46
B 48.5
(3)
A 		40.2
(1.8)
A 		16.8
(-1.5)
A 		26.7
(-0.1)
A 		6.2
(-3)
A 		17.6
(-1.4)
A 		42
C 33.3
(3)
A 		33.3
(3)
A 		19.8
(-2.2)
A 		17.6
(-3)
P 		30.4
(1.9)
A 		24.2
(-0.5)
A 		16
avr 38.6
(2.5) 		41.1
(3) 		13.8
(-3) 		18.5
(-2) 		20.3
(-1.6) 		15.3
(-2.7) 		27
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189290_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10511
Sequence Type Exemplar sequence
Representative Public ID K11H12.9 NCBI
Target Description K11H12.9 /REP_DB=WormBase Gene ID /WP=CE12162 /TR=P91376 /GB=AAC24403.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067561(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067561 NCBI Caenorhabditis elegans K11H12.9 (K11H12.9) mRNA, complete cds. 11/11 None
SNAP00000015759 ENSEMBL cdna:SNAP chromosome:CEL140:IV:649666:651792:1 11/11 None
GENEFINDER00000015773 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:649666:651792:1 11/11 None
K11H12.9 ENSEMBL cdna:known chromosome:CEL140:IV:649665:652134:1 gene:K11H12.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:649671-651798(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl K11H12.9
Entrez Gene 176889 Entrez gene
SwissProt P91376 EMBL-EBI
WormBase CE30095 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_499962 K11H12.9 [Caenorhabditis elegans] gb|AAC24403.2| Hypothetical protein K11H12.9 [Caenorhabditis elegans] 0.0
blast NP_499962 K11H12.9 [Caenorhabditis elegans] gb|AAC24403.2| Hypothetical protein K11H12.9 [Caenorhabditis elegans] 1.0E-178
blast CAE73730 Hypothetical protein CBG21256 [Caenorhabditis briggsae] 1.0E-173
blast CAE73730 Hypothetical protein CBG21256 [Caenorhabditis briggsae] 1.0E-168
blast CAA09699 p21 activated kinase related protein [Drosophila melanogaster] gb|AAF48629.2| CG18582-PA [Drosophila melanogaster] ref|NP_523375.2| CG18582-PA [Drosophila melanogaster] sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt (p21-activated kinase related protein) (Mushroom bodies tiny protein) 2.0E-11
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 5.6E-9
Pfam IPR000719 EMBL-EBI Protein kinase 5.6E-9
Sequence
Target Sequence 
>C. ELEGANS:189290_AT
gcggttgacacatttcgtggtggccaagatttcacatcagattctcgctgccgtagcgat
gatgcatcagaatggaattgcacatggggacctgacactcagcacgatttacgtcaacac
tgacgcggaactccgtctctcgtcctatggtaaaagcgacgactcttcagaacatcttga
cgagagatatcgagatgacctactctcaatcggcgccattgtttcgcgtttcttgatgaa
cgaggaggaaatgttcaagttctccaagtccagaaatctcaaagatatcgactggagagt
tgtgctcgagggaagcagtgactcgggacttcttgatttcaacgcccgatctctactgtt
ccaacttcttgaaggacgtcaatcggctcgagatttgctccgtcatccgtatttcaaatc
attccgcgctccacagcaccaaactgtcgagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGGTTGACACATTTCGTGGTGGCC 244 293 579 Antisense
ATTTCACATCAGATTCTCGCTGCCG 60 17 607 Antisense
ATTGCACATGGGGACCTGACACTCA 343 3 655 Antisense
GACACTCAGCACGATTTACGTCAAC 305 367 672 Antisense
TCAACACTGACGCGGAACTCCGTCT 313 629 692 Antisense
TCCGTCTCTCGTCCTATGGTAAAAG 479 593 710 Antisense
CGAGATGACCTACTCTCAATCGGCG 637 249 769 Antisense
GACTCGGGACTTCTTGATTTCAACG 224 365 898 Antisense
TCAATCGGCTCGAGATTTGCTCCGT 238 633 957 Antisense
TGCTCCGTCATCCGTATTTCAAATC 653 581 974 Antisense
GCTCCACAGCACCAAACTGTCGAGC 141 299 1006 Antisense
Sequence Source Affymetrix Proprietary Database