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[189284_at] EGF-like domain

Description Y69H2.11 /REP_DB=WormBase Gene ID /WP=CE22829 /TR=Q9U1T9 /GB=CAB63408.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=EGF-like domain
Cluster 6grp_high1_10_10 > 25      6grp_total > 25      4grp_total > 46      6grp_high1_sub > 01_02      6grp_total_sub > Decrease      6grp_rule_based > S2      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 107
1 2 3 4 range
A 126.2
(3)
P 		80.4
(-0.1)
P 		54.7
(-1.9)
A 		38.8
(-3)
A 		87
B 139.2
(3)
P 		57.5
(-1.7)
A 		34.2
(-3)
A 		40.9
(-2.6)
A 		105
C 138.2
(3)
P 		68.9
(-0.9)
A 		31.9
(-3)
A 		46.3
(-2.2)
A 		106
avr 134.5
(3) 		68.9
(-1.2) 		40.3
(-3) 		42
(-2.9) 		94

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 87
1 2 3 4 5 6 range
A 111.4
(3)
P 		107.4
(2.7)
P 		54.4
(-1.7)
M 		39
(-2.9)
A 		65.8
(-0.7)
P 		38.1
(-3)
A 		73
B 118.9
(3)
P 		93.6
(0.9)
P 		96.6
(1.1)
P 		62.3
(-1.7)
P 		47.1
(-3)
P 		59.8
(-1.9)
P 		72
C 86.3
(0.4)
P 		124.5
(3)
P 		58.3
(-1.5)
P 		58.2
(-1.6)
P 		44.4
(-2.5)
A 		37.2
(-3)
A 		87
avr 105.5
(2.7) 		108.5
(3) 		69.8
(-0.7) 		53.2
(-2.2) 		52.4
(-2.3) 		45
(-3) 		64
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 40
1 2 3 4 range
A 46
(3)
P 		17.5
(-1.2)
P 		14.3
(-1.7)
A 		5.7
(-3)
A 		40
B 44.4
(3)
P 		14.2
(-2)
A 		7.9
(-3)
A 		8.7
(-2.9)
A 		37
C 45.8
(3)
P 		19.8
(-1.1)
A 		11.1
(-2.5)
A 		7.8
(-3)
A 		38
avr 45.4
(3) 		17.2
(-1.5) 		11.1
(-2.4) 		7.4
(-3) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 20.5
(-0.7)
P 		38.2
(3)
P 		11.8
(-2.5)
M 		9.9
(-2.9)
A 		19.8
(-0.8)
P 		9.3
(-3)
A 		29
B 41.4
(3)
P 		31.2
(0.5)
P 		23.4
(-1.3)
P 		16.5
(-3)
P 		19.1
(-2.4)
P 		22.3
(-1.6)
P 		25
C 32
(1.6)
P 		38
(3)
P 		14.8
(-2.3)
P 		11.7
(-3)
P 		14.4
(-2.4)
A 		12.5
(-2.8)
A 		26
avr 31.3
(1.8) 		35.8
(3) 		16.7
(-2) 		12.7
(-3) 		17.8
(-1.7) 		14.7
(-2.5) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189284_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14088
Sequence Type Exemplar sequence
Representative Public ID Y69H2.11 NCBI
Target Description Y69H2.11 /REP_DB=WormBase Gene ID /WP=CE22829 /TR=Q9U1T9 /GB=CAB63408.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=EGF-like domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075238(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075238 NCBI Caenorhabditis elegans Y69H2.11 (Y69H2.11) mRNA, complete cds. 11/11 None
SNAP00000002596 ENSEMBL cdna:SNAP chromosome:CEL140:V:18633167:18658739:1 11/11 None
GENEFINDER00000002613 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:18643083:18658587:1 11/11 None
Y69H2.11 ENSEMBL cdna:known chromosome:CEL140:V:18643083:18650966:1 gene:Y69H2.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:18643082-18650923(+) 100.0 100.0
Public Domain and Genome References
Gene Title EGF-like domain
Ensembl Y69H2.11
Entrez Gene 180219 Entrez gene
SwissProt Q9U1T9 EMBL-EBI
WormBase CE22829 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6814 sodium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5272 sodium channel activity inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB63408 Hypothetical protein Y69H2.11 [Caenorhabditis elegans] ref|NP_507639.1| Y69H2.11 [Caenorhabditis elegans] 0.0
blast CAB11570 Hypothetical protein Y69H2.2 [Caenorhabditis elegans] ref|NP_507638.1| Y69H2.2 [Caenorhabditis elegans] 0.0
blast CAB63409 Hypothetical protein Y69H2.12 [Caenorhabditis elegans] ref|NP_507640.1| Y69H2.12 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006209 EMBL-EBI EGF-like domain 6.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 6.6E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 7.3E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-5
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 2.3E-37
Pfam IPR006209 EMBL-EBI EGF-like domain 6.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 6.6E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 7.3E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 3.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 5.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 4.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 2.5E-4
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 1.8E-40
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 9.7E-39
Pfam IPR008160 EMBL-EBI Collagen triple helix repeat 2.1E-4
Pfam IPR008160 EMBL-EBI Collagen triple helix repeat 2.6E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 6.6E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 7.3E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 2.6E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-4
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-9
Pfam IPR006209 EMBL-EBI EGF-like domain 1.5E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 5.4E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 3.8E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 4.3E-5
Pfam IPR006209 EMBL-EBI EGF-like domain 2.5E-4
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 2.3E-37
Pfam IPR001873 EMBL-EBI Na+ channel, amiloride-sensitive 2.1E-27
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_507639.1 1 856-878
Y69H2.11 1 856-878
SNAP00000002596 1 2132-2154
Sequence
Target Sequence 
>C. ELEGANS:189284_AT
tcatgacaagatacaccaggctcgggggaagatatggaaagtgtgtgaagaaaccgtcgg
aggtcaagaactactactatccgggagcttataccactgatggctgcctccgaacatgct
accaagaccgtatgaagcaagagtgcaactgcatggaccccaggtacccccaggcgcctg
gtaacgtgacgtcatgtcagttatccgagcggagttgtgttactgtagcgtcagaagccg
ccggggacccatcgaaatggtgggactgtgtatgcccactgccatgctcgaatcaagagt
actcggtgacttggagcaaggcgaattttgtgaacttgccaataatttgcgggaagtcat
ctgacgtgtcaacctgcaaagcacactacatcgatcagctgatggtctccatagtccttc
cccagctggattttaagatttatgcggagaatcctgctatggatttcaacaagtttctgt
cccagcttggaggtcagctgggtgtactgatgggaattaacctggtcacttttatagaag
tcgtgtttttgctctttggac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCATGACAAGATACACCAGGCTCGG 351 621 2081 Antisense
GCGCCTGGTAACGTGACGTCATGTC 344 287 2254 Antisense
GCGGAGTTGTGTTACTGTAGCGTCA 488 293 2289 Antisense
CGCCGGGGACCCATCGAAATGGTGG 321 195 2319 Antisense
GTGGGACTGTGTATGCCCACTGCCA 209 489 2340 Antisense
GAAGTCATCTGACGTGTCAACCTGC 354 335 2433 Antisense
ACCTGCAAAGCACACTACATCGATC 38 89 2452 Antisense
CAGCTGATGGTCTCCATAGTCCTTC 152 199 2476 Antisense
GTCCTTCCCCAGCTGGATTTTAAGA 366 379 2494 Antisense
TTTCTGTCCCAGCTTGGAGGTCAGC 17 663 2554 Antisense
GAAGTCGTGTTTTTGCTCTTTGGAC 703 335 2617 Antisense
Sequence Source Affymetrix Proprietary Database