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[189281_at] protein kinase

Description R02C2.2 /REP_DB=WormBase Gene ID /WP=CE12478 /TR=O44546 /GB=AAC48229.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 54      4grp_total > 24      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 53
1 2 3 4 range
A 5.6
(-3)
A 		17.5
(-1.6)
A 		43.2
(1.3)
A 		57.9
(3)
A 		52
B 6
(-2.8)
A 		28.5
(3)
A 		7.9
(-2.4)
A 		5.4
(-3)
A 		23
C 30.6
(3)
A 		6
(-3)
A 		21.1
(0.7)
A 		12.8
(-1.3)
A 		25
avr 14.1
(-3) 		17.3
(-1.3) 		24.1
(2.3) 		25.4
(3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 22
1 2 3 4 5 6 range
A 3.9
(-3)
A 		23.6
(2.5)
A 		25.5
(3)
A 		12.3
(-0.7)
A 		4.3
(-2.9)
A 		5.3
(-2.6)
A 		22
B 3.2
(-3)
A 		3.1
(-3)
A 		7.2
(-1.6)
A 		11.2
(-0.2)
A 		3.6
(-2.8)
A 		20.2
(3)
A 		17
C 7.8
(-1.9)
A 		6.3
(-2.3)
A 		9.6
(-1.4)
A 		3.8
(-3)
A 		25.2
(3)
A 		12.1
(-0.7)
A 		21
avr 5
(-3) 		11
(1) 		14.1
(3) 		9.1
(-0.3) 		11
(1) 		12.5
(1.9) 		9
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 2
(-3)
A 		3.8
(-1.8)
A 		11.3
(3)
A 		8.5
(1.2)
A 		9
B 1.9
(-2.3)
A 		7
(3)
A 		1.8
(-2.4)
A 		1.2
(-3)
A 		6
C 10.1
(3)
A 		1.7
(-3)
A 		7.4
(1.1)
A 		2.2
(-2.6)
A 		8
avr 4.7
(-1.5) 		4.2
(-2.6) 		6.8
(3) 		4
(-3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8
1 2 3 4 5 6 range
A 0.7
(-3)
A 		8.4
(3)
A 		5.5
(0.7)
A 		3.1
(-1.1)
A 		1.3
(-2.5)
A 		1.3
(-2.5)
A 		8
B 1.1
(-2.9)
A 		1
(-3)
A 		1.8
(-2.3)
A 		3
(-1.2)
A 		1.5
(-2.5)
A 		7.5
(3)
A 		7
C 2.9
(-1.3)
A 		1.9
(-2.1)
A 		2.4
(-1.7)
A 		0.8
(-3)
A 		8.2
(3)
A 		4
(-0.4)
A 		7
avr 1.6
(-3) 		3.8
(1.9) 		3.2
(0.6) 		2.3
(-1.4) 		3.7
(1.7) 		4.3
(3) 		3
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189281_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15129
Sequence Type Exemplar sequence
Representative Public ID R02C2.2 NCBI
Target Description R02C2.2 /REP_DB=WormBase Gene ID /WP=CE12478 /TR=O44546 /GB=AAC48229.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070761
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
SNAP00000019094 ENSEMBL cdna:SNAP chromosome:CEL140:V:244320:245675:-1 None
GENEFINDER00000019098 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:244320:245675:-1 None
NM_070761 NCBI Caenorhabditis elegans R02C2.2 (R02C2.2) mRNA, complete cds. A 
R02C2.2 ENSEMBL cdna:known chromosome:CEL140:V:244298:245675:-1 gene:R02C2.2 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:243226-245675(-) 95.6 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl R02C2.2
Entrez Gene 178552 Entrez gene
WormBase CE39025 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAC48229 Hypothetical protein R02C2.2 [Caenorhabditis elegans] ref|NP_503162.2| R02C2.2 [Caenorhabditis elegans] 1.0E-169
blast AAC48229 Hypothetical protein R02C2.2 [Caenorhabditis elegans] ref|NP_503162.2| R02C2.2 [Caenorhabditis elegans] 1.0E-165
blast AAF59485 Checkpoint kinase protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024233.1| CHeckpoint Kinase family member (chk-1) [Caenorhabditis elegans] sp|Q9N3Z3|CHK1_CAEEL Serine/threonine-protein kinase chk-1 8.0E-71
blast AAA93318 serine/threonine kinase 8.0E-71
blast AAF59485 Checkpoint kinase protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024233.1| CHeckpoint Kinase family member (chk-1) [Caenorhabditis elegans] sp|Q9N3Z3|CHK1_CAEEL Serine/threonine-protein kinase chk-1 3.0E-69
blast AAA93318 serine/threonine kinase 3.0E-69
Protein Families
Method ID Description E-Value
hanks 1.7.2 AGC group; AGC VII Budding yeast DBF2/20; DBF20 5.0E-57
hanks 1.7.2 AGC group; AGC VII Budding yeast DBF2/20; DBF20 5.0E-55
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 8.9E-61
Pfam IPR000719 EMBL-EBI Protein kinase 4.4E-64
Sequence
Target Sequence 
>C. ELEGANS:189281_AT
atcaagtgcgtgcaatcgccttctccttggaagtatacttctgaacttccggcacaatct
ccttctttggcttcggctcctcatccttcttctctccttccttagcttatnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaacannnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncgactacag
gctctgctggatgcatcagtcccccagaaaacgaaagttgaaagctttgctaaaatgtct
taaagtgcggcaaagagttgagatcaagatttgcgctagacaggttccacagtgcgctag
aatggtggaagaagtctctagaaaggtggacgaggcttgcgtcataaaggttttaa

BLASTn GenBank NR
Note: "n"'s represent regions that are not probed by the probe sequences.
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCAAGTGCGTGCAATCGCCTTCTC 258 27 867 Antisense
ATCGCCTTCTCCTTGGAAGTATACT 365 37 881 Antisense
GACTACAGGCTCTGCTGGATGCATC 527 373 1219 Antisense
ACAGGCTCTGCTGGATGCATCAGTC 578 107 1223 Antisense
CATCAGTCCCCCAGAAAACGAAAGT 83 203 1240 Antisense
GAAAGCTTTGCTAAAATGTCTTAAA 617 359 1266 Antisense
GAGTTGAGATCAAGATTTGCGCTAG 689 397 1301 Antisense
ATTTGCGCTAGACAGGTTCCACAGT 645 17 1315 Antisense
GACAGGTTCCACAGTGCGCTAGAAT 688 367 1325 Antisense
GAAAGGTGGACGAGGCTTGCGTCAT 107 359 1367 Antisense
GAGGCTTGCGTCATAAAGGTTTTAA 470 401 1378 Antisense
Sequence Source Affymetrix Proprietary Database