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[189271_s_at] neurexin I like

Description C29A12.4 /REP_DB=WormBase Gene ID /WP=CE25791 /TR=Q18291 /GB=CAA98243.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=neurexin I like
Cluster 6grp_highest_10_10 > 41      6grp_high1_10_10 > 15      4grp_highest_8_8 > 59      4grp_high_8_8 > 25      6grp_highest_nonorm > 30      6grp_total > 15      4grp_total > 38      6grp_highest_sub > De      6grp_cgc > 32      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 960
1 2 3 4 range
A 1303.6
(3)
P 		592.2
(-2.3)
P 		505.3
(-3)
P 		749.9
(-1.2)
P 		798
B 1387.4
(3)
P 		607.7
(-1.9)
P 		427.7
(-3)
P 		638.7
(-1.7)
P 		960
C 1201.5
(3)
P 		783.5
(-0.6)
P 		495.1
(-3)
P 		641.8
(-1.8)
P 		706
avr 1297.5
(3) 		661.1
(-1.6) 		476
(-3) 		676.8
(-1.5) 		822

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 932
1 2 3 4 5 6 range
A 1353.6
(3)
P 		1147.5
(1.6)
P 		674.1
(-1.7)
P 		630.9
(-2)
P 		653.1
(-1.8)
P 		483.4
(-3)
P 		870
B 1296.9
(3)
P 		999.3
(0.9)
P 		819.1
(-0.4)
P 		703.3
(-1.2)
P 		578.6
(-2.1)
P 		458.8
(-3)
P 		838
C 1055.1
(1.5)
P 		1265.2
(3)
P 		706.2
(-1)
P 		661
(-1.3)
P 		601.2
(-1.7)
P 		421.9
(-3)
P 		843
avr 1235.2
(3) 		1137.3
(2.2) 		733.1
(-0.9) 		665.1
(-1.4) 		611
(-1.8) 		454.7
(-3) 		781
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 376
1 2 3 4 range
A 474.6
(3)
P 		128.6
(-2.7)
P 		132.1
(-2.6)
P 		109.8
(-3)
P 		365
B 442.4
(3)
P 		150.1
(-2.1)
P 		99.1
(-3)
P 		136.1
(-2.4)
P 		343
C 397.7
(3)
P 		225.2
(-0.6)
P 		172.6
(-1.7)
P 		108.2
(-3)
P 		290
avr 438.2
(3) 		168
(-2.1) 		134.6
(-2.7) 		118
(-3) 		320

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 334
1 2 3 4 5 6 range
A 249.5
(-0.3)
P 		408.1
(3)
P 		146.8
(-2.4)
P 		160
(-2.1)
P 		197.1
(-1.4)
P 		117.7
(-3)
P 		290
B 451.2
(3)
P 		332.6
(0.5)
P 		198.9
(-2.4)
P 		186.3
(-2.7)
P 		235.1
(-1.6)
P 		171.1
(-3)
P 		280
C 391.1
(3)
P 		386.1
(2.9)
P 		179.7
(-1.9)
P 		132.9
(-3)
P 		194.5
(-1.6)
P 		141.2
(-2.8)
P 		258
avr 363.9
(2.7) 		375.6
(3) 		175.1
(-2.2) 		159.7
(-2.6) 		208.9
(-1.3) 		143.3
(-3) 		232
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189271_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13887
Sequence Type Exemplar sequence
Representative Public ID C29A12.4 NCBI
Target Description C29A12.4 /REP_DB=WormBase Gene ID /WP=CE25791 /TR=Q18291 /GB=CAA98243.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=neurexin I like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073366(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073366 NCBI Caenorhabditis elegans GLIoTactin (Drosophila neuroligin-like) homolog family member (nrx-1) (nrx-1) mRNA, complete cds. 11/11 None
GENEFINDER00000008272 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10848011:10850870:1 10/11 None
C29A12.4 ENSEMBL cdna:known chromosome:CEL140:V:10827610:10849271:1 gene:C29A12.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000008267 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10827609-10849007(+) 100.0 100.0
Public Domain and Genome References
Gene Title neurexin I like
Gene Symbol nrx-1
Ensembl C29A12.4
Entrez Gene 179503 Entrez gene
SwissProt Q18291 EMBL-EBI
WormBase CE25791 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1589517_AT similar to neurexin 3 isoform beta precursor cfa
CANINE_2:CFA.10242.1.A1_S_AT similar to neurexin 3 isoform beta precursor cfa
CANINE_2:CFAAFFX.26389.1.S1_S_AT similar to neurexin 3 isoform beta precursor cfa
CANINE_2:CFAAFFX.26405.1.S1_AT similar to neurexin 3 isoform beta precursor cfa
CANINE_2:CFAAFFX.26405.1.S1_S_AT similar to neurexin 3 isoform beta precursor cfa
CANINE_2:CFAAFFX.26432.1.S1_AT similar to neurexin 3 isoform beta precursor cfa
DROSOPHILA_2:1625623_AT Neurexin 1 dm
DROSGENOME1:141348_AT Neurexin 1 dm
HG-U133_PLUS_2:215021_S_AT neurexin 3 hs
HG-U133A_2:215021_S_AT neurexin 3 hs
HG-U133A:215021_S_AT neurexin 3 hs
HG-U133_PLUS_2:215020_AT neurexin 3 hs
HG-U133A_2:215020_AT neurexin 3 hs
HG-U133A:215020_AT neurexin 3 hs
HG-U133_PLUS_2:205795_AT neurexin 3 hs
HG-U133A:205795_AT neurexin 3 hs
HG-FOCUS:205795_AT neurexin 3 hs
HG-U133A_2:205795_AT neurexin 3 hs
HU35KSUBA:RC_AA450336_AT neurexin 3 hs
HU35KSUBB:RC_D81133_AT neurexin 3 hs
U133_X3P:G4758827_3P_AT neurexin 3 hs
U133_X3P:HS.247837.0.S1_3P_S_AT neurexin 3 hs
U133_X3P:HS.247837.0.S1_3P_AT neurexin 3 hs
U133_X3P:HS.22269.1.A1_3P_AT neurexin 3 hs
U133_X3P:215020_3P_AT neurexin 3 hs
HG-U133_PLUS_2:229649_AT neurexin 3 hs
HG-U133B:229649_AT neurexin 3 hs
HG-U95AV2:35951_AT neurexin 3 hs
HG-U95B:44016_AT neurexin 3 hs
HG-U133_PLUS_2:236750_AT Neurexin 3 hs
HG-U133B:236750_AT Neurexin 3 hs
HG-U95B:41919_AT Neurexin 3 hs
HG-U95C:51259_AT Neurexin 3 hs
HG-U95C:65383_AT Neurexin 3 hs
HG-U95E:79688_AT Neurexin 3 hs
HU35KSUBB:RC_AA021057_AT Neurexin 3 hs
HU35KSUBD:RC_AA446000_AT Neurexin 3 hs
U133_X3P:HS.197478.0.A1_3P_AT Neurexin 3 hs
MOE430B:1438193_AT neurexin III mm
MOUSE430_2:1438193_AT neurexin III mm
MG-U74BV2:105808_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1431153_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1431153_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1456137_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1456137_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1419825_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1419825_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1433788_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1433788_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1444700_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1444700_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1457212_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1457212_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOE430B:1460101_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MOUSE430_2:1460101_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MG-U74CV2:166763_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
MU19KSUBB:TC33088_AT Neurexin III, mRNA (cDNA clone MGC:67582 IMAGE:6406001) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7155 cell adhesion inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5198 structural molecule activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98243 Hypothetical protein C29A12.4 [Caenorhabditis elegans] ref|NP_505767.1| GLIoTactin (Drosophila neuroligin-like) homolog family member (nrx-1) [Caenorhabditis elegans] 0.0
blast CAE64902 Hypothetical protein CBG09719 [Caenorhabditis briggsae] 0.0
blast BAA25504.2 KIAA0578 protein [Homo sapiens] 1.0E-142
blast CAB01217 Hypothetical protein C29A12.6 [Caenorhabditis elegans] emb|CAA98248.1| Hypothetical protein C29A12.6 [Caenorhabditis elegans] ref|NP_505768.1| C29A12.6 [Caenorhabditis elegans] 1.0E-118
blast CAE64903 Hypothetical protein CBG09720 [Caenorhabditis briggsae] 1.0E-96
blast CAA98243 Hypothetical protein C29A12.4 [Caenorhabditis elegans] ref|NP_505767.1| GLIoTactin (Drosophila neuroligin-like) homolog family member (nrx-1) [Caenorhabditis elegans] 8.0E-74
Protein Domains
Database ID Description E-Value
Pfam IPR006209 EMBL-EBI EGF-like domain 5.5E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 7.5E-5
Pfam IPR001791 EMBL-EBI Laminin G 8.9E-5
Pfam IPR001791 EMBL-EBI Laminin G 8.5E-6
Pfam IPR001791 EMBL-EBI Laminin G 5.8E-21
Pfam IPR001791 EMBL-EBI Laminin G 5.4E-6
Pfam IPR001791 EMBL-EBI Laminin G 2.4E-5
Pfam IPR001791 EMBL-EBI Laminin G 8.0E-16
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_505767.1 2 12-34,1443-1465
C29A12.4 2 12-34,1443-1465
GENEFINDER00000008272 4 4-23,30-52,115-137,241-263
Sequence
Target Sequence 
>C. ELEGANS:189271_S_AT
gattcaacaggattcttctcgccagtccttccaactgttgccaactttccaactacaaga
cagactgaacatattgataacgaagttactgctctaataacaagtagtttggcaccacaa
aagacacgcccaaagtcaacgcctcacttcacagtatatccagtaagacctacaacgcct
atgggagatacgatcacaacaacaatgcaggccgccacagtaaccgatttcccacgaact
ccactgatcatgtgctccagtttggcagtaattattgccattgctgcagtcgtgttcttt
gttttcaaatgcagacaaaatccgccaaactctgaacactacaccatggctatgaaatct
caatcaggctatacagcaattgctcctgaactttcacctcccatgaaccatgaccggag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTCAACAGGATTCTTCTCGCCAG 283 431 4102 Antisense
CGCCTCACTTCACAGTATATCCAGT 632 257 4241 Antisense
GTAAGACCTACAACGCCTATGGGAG 653 459 4264 Antisense
AACAATGCAGGCCGCCACAGTAACC 16 135 4302 Antisense
TCCCACGAACTCCACTGATCATGTG 15 599 4331 Antisense
GATCATGTGCTCCAGTTTGGCAGTA 560 419 4347 Antisense
TTGCCATTGCTGCAGTCGTGTTCTT 355 701 4376 Antisense
AAAATCCGCCAAACTCTGAACACTA 364 133 4418 Antisense
CTCTGAACACTACACCATGGCTATG 525 229 4431 Antisense
CAGCAATTGCTCCTGAACTTTCACC 684 203 4475 Antisense
CACCTCCCATGAACCATGACCGGAG 219 201 4496 Antisense
Sequence Source Affymetrix Proprietary Database