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[189268_s_at] kynureninase

Description C15H9.7 /REP_DB=WormBase Gene ID /WP=CE06835 /TR=SW:Q18026 /GB=AAB52668.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=kynureninase
Cluster 6grp_highest_10_10 > 26      6grp_high1_10_10 > 51      4grp_highest_8_8 > 17      4grp_high_8_8 > 61      6grp_highest_nonorm > 33      6grp_total > 62      4grp_total > 59      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2548
1 2 3 4 range
A 1755.2
(0.5)
P 		2795.7
(3)
P 		2634.1
(2.6)
P 		248.2
(-3)
P 		2548
B 1685.6
(0.6)
P 		2648.6
(3)
P 		2592.8
(2.9)
P 		248.1
(-3)
P 		2401
C 1812.9
(0.7)
P 		2069.4
(1.4)
P 		2727.4
(3)
P 		294
(-3)
P 		2433
avr 1751.2
(0.7) 		2504.6
(2.6) 		2651.4
(3) 		263.4
(-3) 		2388

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1968
1 2 3 4 5 6 range
A 1236.5
(-1.4)
P 		1977.3
(0.9)
P 		2626.5
(3)
P 		2194.6
(1.6)
P 		1365.9
(-1)
P 		729.4
(-3)
P 		1897
B 1136.1
(-2)
P 		1917.5
(1.2)
P 		2369.9
(3)
P 		2189.4
(2.3)
P 		1345
(-1.1)
P 		885.1
(-3)
P 		1485
C 1145.2
(-1.5)
P 		1861.5
(0.7)
P 		2604.5
(3)
P 		2146.2
(1.6)
P 		1104.2
(-1.6)
P 		658.9
(-3)
P 		1946
avr 1172.6
(-1.6) 		1918.8
(0.9) 		2533.6
(3) 		2176.7
(1.8) 		1271.7
(-1.3) 		757.8
(-3) 		1776
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 914
1 2 3 4 range
A 639.1
(2.5)
P 		606.9
(2.2)
P 		688.6
(3)
P 		36.3
(-3)
P 		652
B 537.5
(1.8)
P 		654.1
(3)
P 		600.8
(2.5)
P 		52.9
(-3)
P 		601
C 600.1
(0.7)
P 		595
(0.6)
P 		950.6
(3)
P 		49.6
(-3)
P 		901
avr 592.2
(1.7) 		618.7
(1.9) 		746.7
(3) 		46.3
(-3) 		700

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 526
1 2 3 4 5 6 range
A 227.9
(-2.4)
P 		703.2
(3)
P 		572
(1.5)
P 		556.6
(1.3)
P 		412.2
(-0.3)
P 		177.6
(-3)
P 		526
B 395.3
(-1.7)
P 		638.3
(3)
P 		575.5
(1.8)
P 		579.9
(1.9)
P 		546.4
(1.2)
P 		330.1
(-3)
P 		308
C 424.5
(-0.2)
P 		568
(1.7)
P 		662.9
(3)
P 		431.6
(-0.1)
P 		357.3
(-1.1)
P 		220.6
(-3)
P 		442
avr 349.2
(-1.4) 		636.5
(3) 		603.5
(2.5) 		522.7
(1.3) 		438.6
(-0) 		242.8
(-3) 		394
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189268_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16536
Sequence Type Exemplar sequence
Representative Public ID C15H9.7 NCBI
Target Description C15H9.7 /REP_DB=WormBase Gene ID /WP=CE06835 /TR=SW:Q18026 /GB=AAB52668.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=kynureninase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076622(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076622 NCBI Caenorhabditis elegans C15H9.7 (kynureninase) mRNA, complete cds. 11/11 None
SNAP00000042803 ENSEMBL cdna:SNAP chromosome:CEL140:X:6106962:6109293:-1 11/11 None
GENEFINDER00000042818 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6106962:6109293:-1 11/11 None
C15H9.7 ENSEMBL cdna:known chromosome:CEL140:X:6106884:6109296:-1 gene:C15H9.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6106961-6109293(-) 100.0 100.0
Public Domain and Genome References
Gene Title kynureninase
Ensembl C15H9.7
Entrez Gene 180883 Entrez gene
SwissProt Q18026 EMBL-EBI
WormBase CE06835 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.9145.1.S1_AT similar to Kynureninase (L-kynurenine hydrolase) cfa
CHICKEN:GGA.7801.1.S1_AT similar to Kynureninase (L-kynurenine hydrolase) gga
HG-U133_PLUS_2:217388_S_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A_2:217388_S_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A:217388_S_AT kynureninase (L-kynurenine hydrolase) hs
HG-U95AV2:40670_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A:204385_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133_PLUS_2:204385_AT kynureninase (L-kynurenine hydrolase) hs
HG-FOCUS:204385_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A_2:204385_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133_PLUS_2:210663_S_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A:210663_S_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A_2:210663_S_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133_PLUS_2:210662_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A:210662_AT kynureninase (L-kynurenine hydrolase) hs
HG-U133A_2:210662_AT kynureninase (L-kynurenine hydrolase) hs
HUGENEFL:U57721_AT kynureninase (L-kynurenine hydrolase) hs
U133_X3P:G4504936_3P_A_AT kynureninase (L-kynurenine hydrolase) hs
U133_X3P:G12654128_3P_AT kynureninase (L-kynurenine hydrolase) hs
U133_X3P:G12654128_3P_A_AT kynureninase (L-kynurenine hydrolase) hs
U133_X3P:210662_3P_AT kynureninase (L-kynurenine hydrolase) hs
HG-U95AV2:40671_G_AT kynureninase (L-kynurenine hydrolase) hs
HG-U95AV2:40672_AT kynureninase (L-kynurenine hydrolase) hs
HG-U95AV2:38492_AT Kynureninase (L-kynurenine hydrolase) hs
HG-U133_PLUS_2:241305_AT Kynureninase (L-kynurenine hydrolase) hs
HG-U133B:241305_AT Kynureninase (L-kynurenine hydrolase) hs
HG-U95AV2:38493_AT Kynureninase (L-kynurenine hydrolase) hs
HG-U95C:52030_AT Kynureninase (L-kynurenine hydrolase) hs
HG-U95E:68048_AT Kynureninase (L-kynurenine hydrolase) hs
U133_X3P:HS.189299.0.A1_3P_AT Kynureninase (L-kynurenine hydrolase) hs
MOUSE430_2:1430570_AT kynureninase (L-kynurenine hydrolase) mm
MOE430B:1430570_AT kynureninase (L-kynurenine hydrolase) mm
MOUSE430_2:1451903_AT kynureninase (L-kynurenine hydrolase) mm
MOUSE430A_2:1451903_AT kynureninase (L-kynurenine hydrolase) mm
MOE430A:1451903_AT kynureninase (L-kynurenine hydrolase) mm
MG-U74BV2:116706_AT kynureninase (L-kynurenine hydrolase) mm
MU19KSUBA:TC17808_AT Kynureninase (L-kynurenine hydrolase), mRNA (cDNA clone MGC:30315 IMAGE:5136970) mm
MU19KSUBC:TC41192_AT Kynureninase (L-kynurenine hydrolase), mRNA (cDNA clone MGC:30315 IMAGE:5136970) mm
RG-U34A:U68168_AT kynureninase (L-kynurenine hydrolase) rn
RAE230A:1398282_AT kynureninase (L-kynurenine hydrolase) rn
RAT230_2:1398282_AT kynureninase (L-kynurenine hydrolase) rn
Protein Similarities
Method ID Description E-Value
blast AAB52668 Hypothetical protein C15H9.7 [Caenorhabditis elegans] ref|NP_509023.1| C15H9.7 [Caenorhabditis elegans] gb|AAG50225.1| kynureninase [Caenorhabditis elegans] sp|Q18026|KYNU_CAEEL Probable kynureninase (L-kynurenine hydrolase) 0.0
blast CAE68870 Hypothetical protein CBG14833 [Caenorhabditis briggsae] 0.0
blast XP_422147 PREDICTED: similar to Kynureninase (L-kynurenine hydrolase) [Gallus gallus] 1.0E-132
Sequence
Target Sequence 
>C. ELEGANS:189268_S_AT
ttccccttcatcttcactggtgggatgttgactttgcctgttggtgctcgtataagtacg
gatgtacaggagctggatcaattggtggtctttttgtccatgaaagatttttgaatgacc
aacgggagcgtatgttgggatggtggagtcataaaatgtcatcgagatttgtcatggaca
atgttctcgacttggacgagggagctgctggttacagaatcagtaaccctccaattcata
ccgtcgctgctatgctgggaagtttgaaggttttcgatcaagtctcacttgaaaaccttc
gtagtcgttcatgctatttgaccgggtacctggagtacttagtgaaaactttgttcggtg
aaaactctgagcaaagaactactaagctctcaatttctatcatcactccagaagagttcc
atcagcgtggttgccaactttctctgaaattctcttctccaatcgacattatttatcctg
agcttgttaaacgcggatgtgcggttgacaaaagatacccgaatgtaatccgtgtcgctc
cagttcatctttacaataactacgtggatattcgcagattcatttccgtgctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCCCTTCATCTTCACTGGTGGGA 284 699 824 Antisense
GATGTTGACTTTGCCTGTTGGTGCT 220 409 847 Antisense
GAAGGTTTTCGATCAAGTCTCACTT 65 335 1089 Antisense
GAAAACCTTCGTAGTCGTTCATGCT 234 353 1114 Antisense
GTTCATGCTATTTGACCGGGTACCT 24 443 1130 Antisense
AAGCTCTCAATTTCTATCATCACTC 223 151 1207 Antisense
GAAGAGTTCCATCAGCGTGGTTGCC 381 339 1234 Antisense
TTCTCTGAAATTCTCTTCTCCAATC 306 693 1263 Antisense
TACCCGAATGTAATCCGTGTCGCTC 607 647 1339 Antisense
TCGCTCCAGTTCATCTTTACAATAA 178 601 1358 Antisense
TATTCGCAGATTCATTTCCGTGCTC 65 665 1392 Antisense
Sequence Source Affymetrix Proprietary Database