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[189260_at] 7TM chemoreceptor, srh family

Description C46E10.10 /REP_DB=WormBase Gene ID /WP=CE20566 /TR=Q9U5A4 /GB=AAD32272.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=chemoreceptor
Cluster 6grp_total > 24      4grp_total > 17      6grp_cgc > 20      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 116
1 2 3 4 range
A 4.1
(-3)
A 		36.8
(-1.3)
A 		29.7
(-1.7)
A 		119.8
(3)
P 		116
B 20.9
(-1.5)
A 		39.1
(3)
A 		30.2
(0.8)
A 		14.7
(-3)
A 		24
C 29.7
(1.6)
A 		12.2
(-3)
A 		15.4
(-2.2)
P 		35
(3)
A 		23
avr 18.2
(-3) 		29.4
(-1.2) 		25.1
(-1.9) 		56.5
(3) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 60
1 2 3 4 5 6 range
A 64.7
(3)
A 		45.7
(1)
A 		40.3
(0.4)
A 		8.7
(-3)
A 		17
(-2.1)
A 		16.1
(-2.2)
A 		56
B 25.3
(-1.3)
A 		20.1
(-3)
A 		37.3
(2.5)
A 		23.5
(-1.9)
A 		22.4
(-2.3)
A 		38.8
(3)
M 		19
C 25.2
(-0.1)
P 		23.8
(-0.3)
M 		7.8
(-2.6)
A 		47.8
(3)
A 		17.3
(-1.2)
A 		4.6
(-3)
A 		43
avr 38.4
(3) 		29.9
(0.4) 		28.5
(-0) 		26.7
(-0.6) 		18.9
(-3) 		19.8
(-2.7) 		20
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 16
1 2 3 4 range
A 1.5
(-3)
A 		8
(-0.6)
A 		7.8
(-0.6)
A 		17.5
(3)
P 		16
B 6.7
(0.3)
A 		9.7
(3)
A 		7
(0.5)
A 		3.1
(-3)
A 		7
C 9.8
(3)
A 		3.5
(-3)
A 		5.4
(-1.2)
P 		5.9
(-0.7)
A 		6
avr 6
(-3) 		7.1
(-0.6) 		6.7
(-1.5) 		8.8
(3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 15
1 2 3 4 5 6 range
A 11.9
(1.2)
A 		16.2
(3)
A 		8.8
(-0.2)
A 		2.2
(-3)
A 		5.1
(-1.8)
A 		3.9
(-2.3)
A 		14
B 8.8
(-1.1)
A 		6.7
(-2.6)
A 		9.1
(-0.9)
A 		6.2
(-3)
A 		9.1
(-0.9)
A 		14.5
(3)
M 		8
C 9.3
(2.8)
P 		7.2
(1.2)
M 		2
(-2.7)
A 		9.6
(3)
A 		5.6
(-0)
A 		1.6
(-3)
A 		8
avr 10
(3) 		10
(3) 		6.6
(-2.1) 		6
(-3) 		6.6
(-2.1) 		6.7
(-2) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189260_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4500
Sequence Type Exemplar sequence
Representative Public ID C46E10.10 NCBI
Target Description C46E10.10 /REP_DB=WormBase Gene ID /WP=CE20566 /TR=Q9U5A4 /GB=AAD32272.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=chemoreceptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062225(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062225 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-100) (srh-100) mRNA, complete cds. 11/11 None
C46E10.10 ENSEMBL cdna:known chromosome:CEL140:II:3713182:3714689:-1 gene:C46E10.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:3713180-3714688(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, srh family
Gene Symbol srh-100
Ensembl C46E10.10
Entrez Gene 183511 Entrez gene
SwissProt Q9U5A4 EMBL-EBI
WormBase CE20566 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAD32272 Serpentine receptor, class h protein 100 [Caenorhabditis elegans] ref|NP_494626.1| Serpentine Receptor, class H family member (srh-100) [Caenorhabditis elegans] 1.0E-176
blast C88108 protein C46E10.7 [imported] - Caenorhabditis elegans 1.0E-171
blast AAD32273 Serpentine receptor, class h protein 99 [Caenorhabditis elegans] ref|NP_494627.1| Serpentine Receptor, class H family member (srh-99) [Caenorhabditis elegans] 1.0E-155
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_494626.1 7 35-52,71-93,108-130,151-173,218-240,261-283,293-315
C46E10.10 7 35-52,71-93,108-130,151-173,218-240,261-283,293-315
Sequence
Target Sequence 
>C. ELEGANS:189260_AT
tattatcttactccactattttcatatttcttataattatcccttccgaccaggaaactg
caaaacttcaagcgttgcaagcttacccctgcccgacacaagagtttttcacgtttccaa
ttctgattctaaactctgattcaacaacttccacatttatagtgattatttttatgccta
tattcatagctcattcagttggtcatggcgtttttcatgttacatggacaatatggtatt
tgtatgttgcaccttcaaatcaagtttcgatagagactcagaagaagcaaaaaacgttcc
tcaaaaatgttatattgcaattttcgattccatcagtattcattttattctcagttgcaa
ttatttttacatctagtttttattcgcaagaaatgatgaatctaggtgtggacgttgcag
gacttcatggcatcggtgaaagtattgcagttattttcgttcattcaccttaccggaaag
ccgctgggcagctaattttcagatggaacgatccacaatctagcacacgagtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATTATCTTACTCCACTATTTTCAT 546 661 485 Antisense
TATCCCTTCCGACCAGGAAACTGCA 651 655 522 Antisense
CCTGCCCGACACAAGAGTTTTTCAC 239 265 572 Antisense
GTTTTTCACGTTTCCAATTCTGATT 254 449 588 Antisense
AGCTCATTCAGTTGGTCATGGCGTT 77 81 672 Antisense
GTTGCACCTTCAAATCAAGTTTCGA 556 439 730 Antisense
GCAATTTTCGATTCCATCAGTATTC 332 323 801 Antisense
GTTGCAGGACTTCATGGCATCGGTG 178 439 898 Antisense
GCAGTTATTTTCGTTCATTCACCTT 471 311 931 Antisense
TTACCGGAAAGCCGCTGGGCAGCTA 144 681 954 Antisense
CGATCCACAATCTAGCACACGAGTT 74 249 993 Antisense
Sequence Source Affymetrix Proprietary Database