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[189238_at] protein kinase

Description W03F8.2 /REP_DB=WormBase Gene ID /WP=CE17272 /TR=O44570 /GB=AAB94189.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 99      4grp_total > 59      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 30
1 2 3 4 range
A 19.8
(-0.6)
A 		21.4
(-0.2)
A 		36.4
(3)
A 		8.7
(-3)
A 		28
B 33.8
(3)
A 		12.3
(-3)
A 		22.7
(-0.1)
A 		18.1
(-1.4)
A 		22
C 8.4
(-3)
A 		38.6
(3)
A 		15.3
(-1.6)
A 		10.8
(-2.5)
A 		30
avr 20.7
(1) 		24.1
(2.7) 		24.8
(3) 		12.5
(-3) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 71
1 2 3 4 5 6 range
A 18.6
(-1.6)
A 		22.9
(-1.3)
A 		2.3
(-3)
A 		21.7
(-1.4)
A 		73.2
(3)
A 		52.5
(1.2)
A 		71
B 48.6
(2)
A 		31.1
(-0.1)
A 		6.4
(-3)
A 		9.6
(-2.6)
A 		54.9
(2.8)
A 		56.8
(3)
A 		50
C 34.6
(-1.3)
A 		26.1
(-2.6)
A 		23.2
(-3)
A 		57.8
(2.1)
A 		64.1
(3)
A 		43
(-0.1)
A 		41
avr 33.9
(-0.4) 		26.7
(-1.2) 		10.6
(-3) 		29.7
(-0.9) 		64.1
(3) 		50.8
(1.5) 		54
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 7.2
(1.3)
A 		4.6
(-0.6)
A 		9.5
(3)
A 		1.3
(-3)
A 		8
B 10.8
(3)
A 		3
(-3)
A 		5.3
(-1.2)
A 		3.8
(-2.4)
A 		8
C 2.8
(-2.4)
A 		11.1
(3)
A 		5.3
(-0.7)
A 		1.8
(-3)
A 		9
avr 6.9
(3) 		6.2
(2.1) 		6.7
(2.7) 		2.3
(-3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 22
1 2 3 4 5 6 range
A 3.4
(-2.2)
A 		8.1
(-0.9)
A 		0.5
(-3)
A 		5.5
(-1.6)
A 		22.1
(3)
A 		12.8
(0.4)
A 		22
B 16.9
(1.4)
A 		10.3
(-0.5)
A 		1.5
(-3)
A 		2.5
(-2.7)
A 		22.3
(3)
A 		21.2
(2.7)
A 		21
C 12.8
(-0.2)
A 		8
(-2.1)
A 		5.9
(-3)
A 		11.6
(-0.7)
A 		20.7
(3)
A 		14.4
(0.4)
A 		15
avr 11
(-0.4) 		8.8
(-1.1) 		2.6
(-3) 		6.5
(-1.8) 		21.7
(3) 		16.1
(1.2) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189238_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10377
Sequence Type Exemplar sequence
Representative Public ID W03F8.2 NCBI
Target Description W03F8.2 /REP_DB=WormBase Gene ID /WP=CE17272 /TR=O44570 /GB=AAB94189.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068338(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068338 NCBI Caenorhabditis elegans W03F8.2 (W03F8.2) mRNA, complete cds. 11/11 None
SNAP00000036706 ENSEMBL cdna:SNAP chromosome:CEL140:IV:5190434:5192536:1 11/11 None
GENEFINDER00000036709 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:5190434:5192536:1 11/11 None
W03F8.2 ENSEMBL cdna:known chromosome:CEL140:IV:5190102:5192509:1 gene:W03F8.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:5190395-5192542(+) 99.95 99.95
Public Domain and Genome References
Gene Title protein kinase
Ensembl W03F8.2
Entrez Gene 189158 Entrez gene
SwissProt O44570 EMBL-EBI
WormBase CE35040 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB94189 Hypothetical protein W03F8.2 [Caenorhabditis elegans] ref|NP_500739.2| W03F8.2 [Caenorhabditis elegans] 0.0
blast NP_501307 T06C10.3 [Caenorhabditis elegans] gb|AAA82300.1| Hypothetical protein T06C10.3 [Caenorhabditis elegans] 0.0
blast AAB94189 Hypothetical protein W03F8.2 [Caenorhabditis elegans] ref|NP_500739.2| W03F8.2 [Caenorhabditis elegans] 1.0E-169
blast CAB02882 Hypothetical protein F01D4.3 [Caenorhabditis elegans] ref|NP_501934.2| F01D4.3 [Caenorhabditis elegans] 1.0E-165
blast CAB02882 Hypothetical protein F01D4.3 [Caenorhabditis elegans] ref|NP_501934.2| F01D4.3 [Caenorhabditis elegans] 1.0E-161
blast T23792 hypothetical protein M176.9 - Caenorhabditis elegans 1.0E-155
blast NP_501307 T06C10.3 [Caenorhabditis elegans] gb|AAA82300.1| Hypothetical protein T06C10.3 [Caenorhabditis elegans] 1.0E-147
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 9.2E-33
Pfam IPR000719 EMBL-EBI Protein kinase 7.6E-45
Pfam IPR000719 EMBL-EBI Protein kinase 7.6E-45
Sequence
Target Sequence 
>C. ELEGANS:189238_AT
caagttttgtcgtggagcaggcagagggatcgatgacatcgctgctcgtaactgtcttct
tcacgaaaaagttgtcaagatcaccgactttggtctctccagaactggaccagcctacaa
aatgaagacggcttgcaagcttccagtcaaatggctcgctccggagactttgacaacact
cacgttctcctttgctactgatgtctggggagtcacctgctacgaagtgtttgctgatgg
tatcgaaccgttctttggaattcaaaattccgtggtgaagaccgacattgtcgcgaacaa
attcctgcagatgccttccaacactcctgaatctatcaagaagtacatggatgcttcgat
ttttgtcgaaggatcgcgtcgtgctactatgacgtcggcaattgctgagttcaaaaagat
caagttggctctagaacgtcctacttcagata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAGTTTTGTCGTGGAGCAGGCAGA 102 185 1332 Antisense
GATCGATGACATCGCTGCTCGTAAC 512 417 1359 Antisense
TGCTCGTAACTGTCTTCTTCACGAA 446 581 1374 Antisense
TCTCCAGAACTGGACCAGCCTACAA 18 611 1427 Antisense
GAGACTTTGACAACACTCACGTTCT 668 393 1495 Antisense
TTCTCCTTTGCTACTGATGTCTGGG 230 693 1516 Antisense
GCTGATGGTATCGAACCGTTCTTTG 19 295 1564 Antisense
ACAAATTCCTGCAGATGCCTTCCAA 657 111 1628 Antisense
CTTCCAACACTCCTGAATCTATCAA 456 219 1646 Antisense
GACGTCGGCAATTGCTGAGTTCAAA 75 379 1722 Antisense
GCTCTAGAACGTCCTACTTCAGATA 323 299 1759 Antisense
Sequence Source Affymetrix Proprietary Database