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[189195_at] phosphatase

Description T23F11.1 /REP_DB=WormBase Gene ID /WP=CE24009 /TR=SW:P49596 /GB=CAA86456.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=phosphatase
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 06      4grp_highest_8_8 > 50      4grp_high_8_8 > 40      6grp_highest_nonorm > 41      6grp_total > 07      4grp_total > 47      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 873
1 2 3 4 range
A 1314.8
(3)
P 		694.5
(-2.5)
P 		636.7
(-3)
P 		648.1
(-2.9)
P 		678
B 1253.4
(3)
P 		646.5
(-2.5)
P 		589.4
(-3)
P 		620.7
(-2.7)
P 		664
C 1351.2
(3)
P 		720.3
(-1.3)
P 		745.1
(-1.2)
P 		478.6
(-3)
P 		873
avr 1306.5
(3) 		687.1
(-2.1) 		657.1
(-2.4) 		582.5
(-3) 		724

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 796
1 2 3 4 5 6 range
A 1001.1
(3)
P 		796.4
(0.3)
P 		640.3
(-1.7)
P 		630.3
(-1.9)
P 		545.2
(-3)
P 		692.4
(-1.1)
P 		456
B 1035.9
(3)
P 		760.9
(-0.4)
P 		704.3
(-1.1)
P 		687.7
(-1.3)
P 		553.6
(-3)
P 		638
(-2)
P 		482
C 1315.5
(3)
P 		703.6
(-1.6)
P 		1021.1
(0.8)
P 		662.4
(-1.9)
P 		519.7
(-3)
P 		533.4
(-2.9)
P 		796
avr 1117.5
(3) 		753.6
(-0.8) 		788.6
(-0.4) 		660.1
(-1.7) 		539.5
(-3) 		621.3
(-2.2) 		578
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 398
1 2 3 4 range
A 478.7
(3)
P 		150.8
(-2.1)
P 		166.4
(-1.9)
P 		94.9
(-3)
P 		384
B 399.7
(3)
P 		159.7
(-2.4)
P 		136.6
(-2.9)
P 		132.3
(-3)
P 		267
C 447.3
(3)
P 		207.1
(-0.9)
P 		259.7
(-0.1)
P 		80.7
(-3)
P 		367
avr 441.9
(3) 		172.5
(-1.8) 		187.6
(-1.5) 		102.6
(-3) 		339

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 354
1 2 3 4 5 6 range
A 184.5
(-1.1)
P 		283.2
(3)
P 		139.4
(-3)
P 		159.9
(-2.1)
P 		164.5
(-2)
P 		168.6
(-1.8)
P 		144
B 360.5
(3)
P 		253.3
(-0.4)
P 		171
(-3)
P 		182.1
(-2.6)
P 		224.9
(-1.3)
P 		237.9
(-0.9)
P 		190
C 487.6
(3)
P 		214.7
(-1.6)
P 		259.9
(-0.9)
P 		133.2
(-3)
P 		168.2
(-2.4)
P 		178.5
(-2.2)
P 		354
avr 344.2
(3) 		250.4
(-0) 		190.1
(-2) 		158.4
(-3) 		185.9
(-2.1) 		195
(-1.8) 		186
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189195_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7286
Sequence Type Exemplar sequence
Representative Public ID T23F11.1 NCBI
Target Description T23F11.1 /REP_DB=WormBase Gene ID /WP=CE24009 /TR=SW:P49596 /GB=CAA86456.2 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065548(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065548 NCBI Caenorhabditis elegans T23F11.1 (phosphatase) mRNA, complete cds. 11/11 None
SNAP00000039542 ENSEMBL cdna:SNAP chromosome:CEL140:III:4650461:4653147:1 11/11 None
GENEFINDER00000039550 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4650461:4653147:1 11/11 None
T23F11.1.2 ENSEMBL cdna:known chromosome:CEL140:III:4650357:4653885:1 gene:T23F11.1 11/11 A 
T23F11.1.1 ENSEMBL cdna:known chromosome:CEL140:III:4650457:4653885:1 gene:T23F11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4650460-4653147(+) 100.0 100.0
Public Domain and Genome References
Gene Title phosphatase
Ensembl T23F11.1
Entrez Gene 175610 Entrez gene
SwissProt P49596 EMBL-EBI
WormBase CE24009 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13128_AT protein phosphatase 2C, putative / PP2C, putative at
ATH1-121501:253453_AT protein phosphatase 2C, putative / PP2C, putative at
DROSOPHILA_2:1631724_S_AT dm
DROSGENOME1:154425_AT dm
YEAST_2:1774521_AT Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8287 protein serine/threonine phosphatase complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4722 protein serine/threonine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA86456 Hypothetical protein T23F11.1 [Caenorhabditis elegans] ref|NP_497949.1| T23F11.1 [Caenorhabditis elegans] sp|P49596|PP2C2_CAEEL Probable protein phosphatase 2C T23F11.1 (PP2C) 0.0
blast E88434 protein T23F11.1 [imported] - Caenorhabditis elegans 0.0
blast CAE71168 Hypothetical protein CBG18025 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001932 EMBL-EBI Protein phosphatase 2C-like 3.7E-98
Sequence
Target Sequence 
>C. ELEGANS:189195_AT
gtccactttcattcgatcacaagccatctcatgaaaccgaagctcgacgtatcattgccg
ccggtggatgggttgagttcaatcgtgtcaatggtaatttggcactttcccgtgctctcg
gagattttgcattcaaaaattgtgacacaaagcctgctgaggagcaaattgtcactgcat
tcccggatgtgatcactgacaagctgacaccggatcacgagtttattgttcttgcatgtg
atggtatttgggatgtaatgacaaatcaggaagtcgtagattttgttcgtgagaagcttg
ctgagaagagggatccacaatcgatttgcgaagagcttctcactcggtgcttggctccag
attgtcagatgggtggtctcggatgcgataatatgactgttgttctcgtgggacttcttc
atggacaatccccagatacacttttcac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCCACTTTCATTCGATCACAAGCC 6 477 455 Antisense
ACCGAAGCTCGACGTATCATTGCCG 393 89 490 Antisense
ATTGCCGCCGGTGGATGGGTTGAGT 358 7 508 Antisense
TGGTAATTTGGCACTTTCCCGTGCT 122 549 546 Antisense
TTCCCGTGCTCTCGGAGATTTTGCA 178 699 561 Antisense
TGCATTCCCGGATGTGATCACTGAC 525 563 630 Antisense
ACAAGCTGACACCGGATCACGAGTT 277 111 653 Antisense
CGGTGCTTGGCTCCAGATTGTCAGA 412 243 799 Antisense
GTCAGATGGGTGGTCTCGGATGCGA 317 467 818 Antisense
TATGACTGTTGTTCTCGTGGGACTT 661 651 846 Antisense
GACAATCCCCAGATACACTTTTCAC 706 363 878 Antisense
Sequence Source Affymetrix Proprietary Database