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[189192_at] carboxyesterase

Description C23H4.5 /REP_DB=WormBase Gene ID /WP=CE08331 /TR=Q93253 /GB=CAB01679.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=carboxyesterase
Cluster 6grp_total > 83      4grp_total > 26      6grp_total_sub > Hat      6grp_rule_based > S5      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 58
1 2 3 4 range
A 5.2
(-2.5)
A 		1.3
(-3)
A 		8.2
(-2.2)
A 		53.1
(3)
A 		52
B 3.3
(-3)
A 		58.9
(3)
A 		26.9
(-0.5)
A 		28
(-0.3)
A 		56
C 3.5
(-3)
A 		35.9
(1.1)
A 		17.2
(-1.3)
A 		51.5
(3)
A 		48
avr 4
(-3) 		32
(1.2) 		17.4
(-1) 		44.2
(3) 		40

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 207
1 2 3 4 5 6 range
A 2.7
(-2.9)
A 		1.2
(-3)
A 		16.5
(-2.4)
A 		103.6
(1.2)
P 		148.6
(3)
P 		36.5
(-1.6)
A 		147
B 2.6
(-3)
A 		22.4
(-2.4)
A 		9.8
(-2.8)
A 		109.2
(0.1)
P 		207.7
(3)
P 		23.2
(-2.4)
A 		205
C 1.2
(-3)
A 		2.5
(-2.9)
A 		3.4
(-2.9)
A 		98.5
(1)
P 		148.1
(3)
P 		28.9
(-1.9)
P 		147
avr 2.2
(-3) 		8.7
(-2.8) 		9.9
(-2.7) 		103.8
(0.7) 		168.1
(3) 		29.5
(-2) 		166
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 1.9
(-1.7)
A 		0.3
(-3)
A 		2.1
(-1.6)
A 		7.8
(3)
A 		8
B 1
(-3)
A 		14.6
(3)
A 		6.2
(-0.7)
A 		6
(-0.8)
A 		14
C 1.1
(-3)
A 		10.3
(3)
A 		6
(0.2)
A 		8.7
(2)
A 		9
avr 1.3
(-3) 		8.4
(3) 		4.8
(-0) 		7.5
(2.2) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 84
1 2 3 4 5 6 range
A 0.5
(-3)
A 		0.4
(-3)
A 		3.6
(-2.6)
A 		26.3
(0.5)
P 		44.9
(3)
P 		8.9
(-1.9)
A 		45
B 0.9
(-3)
A 		7.5
(-2.5)
A 		2.4
(-2.9)
A 		28.9
(-1)
P 		84.4
(3)
P 		8.7
(-2.4)
A 		84
C 0.4
(-3)
A 		0.8
(-2.9)
A 		0.9
(-2.9)
A 		19.8
(-0.5)
P 		47.9
(3)
P 		9.7
(-1.8)
P 		48
avr 0.6
(-3) 		2.9
(-2.8) 		2.3
(-2.8) 		25
(-0.5) 		59.1
(3) 		9.1
(-2.1) 		59
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189192_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17029
Sequence Type Exemplar sequence
Representative Public ID C23H4.5 NCBI
Target Description C23H4.5 /REP_DB=WormBase Gene ID /WP=CE08331 /TR=Q93253 /GB=CAB01679.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=carboxyesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077638(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077638 NCBI Caenorhabditis elegans C23H4.4 (carboxyesterase) mRNA, complete cds. 11/11 A 
GENEFINDER00000004848 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:12219631:12233363:1 11/11 None
C23H4.4 ENSEMBL cdna:known chromosome:CEL140:X:12229872:12232907:1 gene:C23H4.4 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000004843 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:12231488-12232907(+) 100.0 100.0
Public Domain and Genome References
Gene Title carboxyesterase
Ensembl C23H4.4
Entrez Gene 182819 Entrez gene
SwissProt Q93252 EMBL-EBI
WormBase CE31419 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6233 dTDP biosynthesis inferred from electronic annotation QuickGO AmiGO
6235 dTTP biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4798 thymidylate kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01678 Hypothetical protein C23H4.4 [Caenorhabditis elegans] ref|NP_510039.2| C23H4.4 [Caenorhabditis elegans] 0.0
blast CAE69912 Hypothetical protein CBG16268 [Caenorhabditis briggsae] 0.0
blast CAD44098 Hypothetical protein C23H4.7 [Caenorhabditis elegans] ref|NP_741910.1| C23H4.7 [Caenorhabditis elegans] 0.0
blast CAE69912 Hypothetical protein CBG16268 [Caenorhabditis briggsae] 1.0E-165
blast CAD44098 Hypothetical protein C23H4.7 [Caenorhabditis elegans] ref|NP_741910.1| C23H4.7 [Caenorhabditis elegans] 1.0E-145
Protein Domains
Database ID Description E-Value
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 2.3E-86
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 7.4E-7
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 5.4E-95
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 7.3E-83
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 6.0E-7
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 8.3E-82
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 2.3E-86
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 7.4E-7
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510039.2 1 578-597
C23H4.4 1 578-597
GENEFINDER00000004848 1 2144-2161
Sequence
Target Sequence 
>C. ELEGANS:189192_AT
atttgtttccgctgcaacatattctgaagctctaacgaatgctggaggaaacgtgtacct
atttgaatctcgtcaaaaacctttcagcatgcatgtgacggatatgcagtattttatcgg
cattcatcgggaaaaaaaccataccactgatatggatattttagattcattttattcaaa
actgcttgtcaattttacaaaatttggttcaccgtctccaaactgggaaaaatatgaccc
ttctaagatgaatttcatggctatggagatcgacacagagcaaggaattgagccaaaaat
ggaaaacggttttcatgaagagttggtcaatttctggttgattaacatgatgcagattga
tagaaatattatagaaatgaaattaaatggggagtataactcgtttgatggacgtgccca
attaactactaaacatattggtgttccaacttcattgccaattatttatgctcctgctgt
atcggatcctgaaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTTGTTTCCGCTGCAACATATTCT 653 17 306 Antisense
GAAACGTGTACCTATTTGAATCTCG 684 357 353 Antisense
GAATCTCGTCAAAAACCTTTCAGCA 376 329 370 Antisense
AACCTTTCAGCATGCATGTGACGGA 148 147 383 Antisense
GCAGTATTTTATCGGCATTCATCGG 327 311 411 Antisense
AATTTGGTTCACCGTCTCCAAACTG 702 171 506 Antisense
TCATGGCTATGGAGATCGACACAGA 499 621 560 Antisense
ATAACTCGTTTGATGGACGTGCCCA 599 23 701 Antisense
GACGTGCCCAATTAACTACTAAACA 362 337 716 Antisense
TGCCAATTATTTATGCTCCTGCTGT 245 587 761 Antisense
CTCCTGCTGTATCGGATCCTGAAAA 454 235 776 Antisense
Sequence Source Affymetrix Proprietary Database