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[189191_at] protein kinase

Description R11E3.1 /REP_DB=WormBase Gene ID /WP=CE19543 /TR=Q9TYX4 /GB=AAK39263.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 77      4grp_total > 36      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 84
1 2 3 4 range
A 31.3
(-3)
A 		63.8
(0.3)
A 		33.3
(-2.8)
A 		89.7
(3)
A 		58
B 83.4
(3)
A 		83.6
(3)
A 		5.6
(-3)
A 		54.8
(0.8)
A 		78
C 38.7
(-3)
A 		61.2
(3)
A 		42.7
(-1.9)
A 		47.7
(-0.6)
A 		23
avr 51.1
(0.4) 		69.5
(3) 		27.2
(-3) 		64.1
(2.2) 		42

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 143
1 2 3 4 5 6 range
A 94.8
(-0.6)
A 		65.8
(-2)
A 		51.7
(-2.6)
A 		43.2
(-3)
A 		86.5
(-1)
P 		174.2
(3)
P 		131
B 41.8
(-2.5)
A 		31.7
(-3)
A 		39.6
(-2.6)
A 		67.1
(-1.1)
A 		91.8
(0.2)
P 		144.5
(3)
P 		113
C 42.5
(-2.7)
A 		37.4
(-3)
A 		86.1
(-0.3)
M 		79.8
(-0.6)
A 		77.2
(-0.8)
P 		143.9
(3)
P 		107
avr 59.7
(-2.2) 		45
(-3) 		59.1
(-2.2) 		63.4
(-2) 		85.2
(-0.8) 		154.2
(3) 		109
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 25
1 2 3 4 range
A 11.4
(0.1)
A 		13.9
(3)
A 		8.7
(-3)
A 		13.1
(2.1)
A 		5
B 26.6
(3)
A 		20.6
(1.6)
A 		1.3
(-3)
A 		11.7
(-0.5)
A 		25
C 12.8
(0)
A 		17.6
(3)
A 		14.9
(1.3)
A 		8
(-3)
A 		10
avr 16.9
(2.7) 		17.4
(3) 		8.3
(-3) 		10.9
(-1.3) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 17.5
(-1.8)
A 		23.4
(-0.6)
A 		11.3
(-2.9)
A 		11
(-3)
A 		26.1
(-0.1)
P 		42.4
(3)
P 		31
B 14.5
(-2.3)
A 		10.5
(-2.9)
A 		9.6
(-3)
A 		17.8
(-1.9)
A 		37.3
(0.8)
P 		53.9
(3)
P 		44
C 15.8
(-2.3)
A 		11.4
(-3)
A 		21.9
(-1.3)
M 		16
(-2.3)
A 		25
(-0.8)
P 		48.2
(3)
P 		37
avr 15.9
(-2.7) 		15.1
(-2.9) 		14.3
(-3) 		14.9
(-2.9) 		29.5
(-0.3) 		48.2
(3) 		34
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189191_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11170
Sequence Type Exemplar sequence
Representative Public ID R11E3.1 NCBI
Target Description R11E3.1 /REP_DB=WormBase Gene ID /WP=CE19543 /TR=Q9TYX4 /GB=AAK39263.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068243(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068243 NCBI Caenorhabditis elegans R11E3.1 (R11E3.1) mRNA, complete cds. 11/11 None
SNAP00000009827 ENSEMBL cdna:SNAP chromosome:CEL140:IV:4789764:4793778:1 11/11 None
GENEFINDER00000009845 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:4789764:4791930:1 11/11 None
R11E3.1 ENSEMBL cdna:known chromosome:CEL140:IV:4789726:4791949:1 gene:R11E3.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_001026379 1/11 Cross Hyb Matching Probes None
SNAP00000041851 1/11 Cross Hyb Matching Probes None
GENEFINDER00000041871 1/11 Cross Hyb Matching Probes None
K07A1.14 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:4789769-4791854(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl R11E3.1
Entrez Gene 187810 Entrez gene
SwissProt Q9TYX4 EMBL-EBI
WormBase CE37268 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK39263 Hypothetical protein R11E3.1 [Caenorhabditis elegans] ref|NP_500644.2| R11E3.1 [Caenorhabditis elegans] 0.0
blast CAE66667 Hypothetical protein CBG12006 [Caenorhabditis briggsae] 0.0
blast CAE60552 Hypothetical protein CBG04179 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
hanks 1.9.5 AGC group; AGC Other; DdK2 6.0E-64
hanks 1.9.5 AGC group; AGC Other; DdK2 3.0E-64
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.0E-66
Sequence
Target Sequence 
>C. ELEGANS:189191_AT
gacattgcagctcgtaactgcctatattcgaatgataaagtggtcaagctctcggatttt
ggactttctgtagttggaaatcaatacaaactctgcgcagctcagaagcttccgatcaaa
tggcttgcacctgaaacaattacaactcgcttcttcactccgaagactgatgtctacagc
tatggagtcatgtgcttcgagatattttcgaatggagcagaaccatgggaaggtgtcacg
aatactgttacaaagaataatgtggtcaacggaataaacttggttattcctgaatcctgc
ccagagaaatttcgatcatttgtgcatgagaagatcttcgtggttgatcctaaaagacgt
gttgttatggatgacgtcagcagatttattgaaccaattatcaatgatatgcataatgct
gcagctgttagtacaatgctcaatcttgcttcagataagtctgactacaaccagaagaca
tccgatgcaaatcgttcaatgatggtaccaaatcttactagttcaactcctcgcaatgct
acaaattcgatgaaacagaatgattaccgccgcaag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACATTGCAGCTCGTAACTGCCTAT 397 371 1021 Antisense
AGCTCTCGGATTTTGGACTTTCTGT 597 79 1067 Antisense
ATCAATACAAACTCTGCGCAGCTCA 108 27 1100 Antisense
TGCGCAGCTCAGAAGCTTCCGATCA 74 579 1114 Antisense
GCTTCCGATCAAATGGCTTGCACCT 115 307 1128 Antisense
AAACAATTACAACTCGCTTCTTCAC 669 127 1154 Antisense
CTCGCTTCTTCACTCCGAAGACTGA 576 233 1166 Antisense
TTATTCCTGAATCCTGCCCAGAGAA 141 679 1304 Antisense
GTACAATGCTCAATCTTGCTTCAGA 396 461 1451 Antisense
GTTCAACTCCTCGCAATGCTACAAA 58 445 1541 Antisense
GAAACAGAATGATTACCGCCGCAAG 689 355 1572 Antisense
Sequence Source Affymetrix Proprietary Database