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[189166_at] protein kinase

Description ZK354.6 /REP_DB=WormBase Gene ID /WP=CE15320 /TR=P91566 /GB=AAB42262.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 77      4grp_total > 10      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 4
(-3)
A 		6
(0)
A 		5.5
(-0.8)
A 		8
(3)
A 		4
B 4.8
(-1.9)
A 		5.3
(-1.6)
A 		3.2
(-3)
A 		12
(3)
A 		9
C 4.2
(-2.3)
A 		4.5
(-2.1)
A 		2.7
(-3)
A 		14.7
(3)
A 		12
avr 4.3
(-2.6) 		5.3
(-1.8) 		3.8
(-3) 		11.6
(3) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 101
1 2 3 4 5 6 range
A 2.6
(-3)
A 		3.4
(-2.9)
A 		3.2
(-2.9)
A 		3.9
(-2.9)
A 		45.1
(1)
A 		66
(3)
A 		63
B 3.7
(-2.9)
A 		2.8
(-3)
A 		3.5
(-2.9)
A 		4.1
(-2.9)
A 		7.3
(-2.7)
A 		83.6
(3)
A 		81
C 2.7
(-3)
A 		3.4
(-3)
A 		3.9
(-2.9)
A 		3.5
(-3)
A 		5.3
(-2.8)
A 		103.7
(3)
A 		101
avr 3
(-3) 		3.2
(-3) 		3.5
(-3) 		3.8
(-2.9) 		19.2
(-1.8) 		84.4
(3) 		81
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2
1 2 3 4 range
A 1.5
(3)
A 		1.3
(-1)
A 		1.4
(1)
A 		1.2
(-3)
A 		0
B 1.5
(-0.5)
A 		1.3
(-1.1)
A 		0.7
(-3)
A 		2.6
(3)
A 		2
C 1.4
(-1.1)
A 		1.3
(-1.5)
A 		0.9
(-3)
A 		2.5
(3)
A 		2
avr 1.5
(-0.3) 		1.3
(-1.4) 		1
(-3) 		2.1
(3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 34
1 2 3 4 5 6 range
A 0.5
(-3)
A 		1.2
(-2.7)
A 		0.7
(-2.9)
A 		1
(-2.8)
A 		13.6
(2)
A 		16.1
(3)
A 		16
B 1.3
(-2.9)
A 		0.9
(-3)
A 		0.9
(-3)
A 		1.1
(-3)
A 		3
(-2.6)
A 		31.2
(3)
A 		30
C 1
(-2.9)
A 		1
(-2.9)
A 		1
(-2.9)
A 		0.7
(-3)
A 		1.7
(-2.8)
A 		34.7
(3)
A 		34
avr 0.9
(-3) 		1
(-3) 		0.9
(-3) 		0.9
(-3) 		6.1
(-1.8) 		27.3
(3) 		26
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189166_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11209
Sequence Type Exemplar sequence
Representative Public ID ZK354.6 NCBI
Target Description ZK354.6 /REP_DB=WormBase Gene ID /WP=CE15320 /TR=P91566 /GB=AAB42262.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068371(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068371 NCBI Caenorhabditis elegans ZK354.6 (ZK354.6) mRNA, complete cds. 11/11 None
SNAP00000006005 ENSEMBL cdna:SNAP chromosome:CEL140:IV:5295961:5297476:-1 11/11 None
GENEFINDER00000006019 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:5295961:5297320:-1 11/11 None
ZK354.6 ENSEMBL cdna:known chromosome:CEL140:IV:5295961:5297476:-1 gene:ZK354.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:5295966-5297482(-) 88.17 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl ZK354.6
Entrez Gene 191293 Entrez gene
SwissProt P91566 EMBL-EBI
WormBase CE15320 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB42262 Hypothetical protein ZK354.6 [Caenorhabditis elegans] ref|NP_500772.1| ZK354.6 [Caenorhabditis elegans] 0.0
blast CAE64365 Hypothetical protein CBG09052 [Caenorhabditis briggsae] 1.0E-155
blast CAE64365 Hypothetical protein CBG09052 [Caenorhabditis briggsae] 1.0E-151
blast NP_497995 F26A1.4 [Caenorhabditis elegans] gb|AAA68246.4| Hypothetical protein F26A1.4 [Caenorhabditis elegans] 1.0E-91
blast NP_497995 F26A1.4 [Caenorhabditis elegans] gb|AAA68246.4| Hypothetical protein F26A1.4 [Caenorhabditis elegans] 2.0E-91
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.1E-19
Pfam IPR000719 EMBL-EBI Protein kinase 4.1E-19
Sequence
Target Sequence 
>C. ELEGANS:189166_AT
acgaatcactgagcggactctctaccgggcaatgatacaagttctaaaggctctttcgtt
ggttcatggtgctggattcttgcatcgagatttgaaaccatccaattgttgtatcggtgc
aattgattgtactcgtatttacttgattgattatggtctaactcgtcaataccttgataa
gggtggaatcgtccgtaaaccccgagctggagttggtcttcgtggtaccgtccgttatat
gagtttggatgctcatgcacgtcaagacctcggccccaaaaacgacttggttgctttcct
ctacacaacgattgaatgtggagatggatatcttccatggtcgcacgagaaaacccatga
aaacataatcaagttgaaacaagcacacattggagacaagctgtgtacgaagcaaccggt
tatgacaaaagccgcagagtacattgagtctctaaattatcacagtattccggattatga
gaagttgctcgcattgatggaagaatgcaatccaccggatcttaaggaaagcgagcctta
cgactggcagtaccgtcatcttcctaatggaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACGAATCACTGAGCGGACTCTCTAC 235 89 501 Antisense
GGACTCTCTACCGGGCAATGATACA 497 523 515 Antisense
CTAAAGGCTCTTTCGTTGGTTCATG 222 227 544 Antisense
CGTTGGTTCATGGTGCTGGATTCTT 9 249 557 Antisense
ATGGTCTAACTCGTCAATACCTTGA 440 49 653 Antisense
TCTTCGTGGTACCGTCCGTTATATG 117 547 717 Antisense
TTGCTTTCCTCTACACAACGATTGA 442 703 791 Antisense
GATGGATATCTTCCATGGTCGCACG 520 407 823 Antisense
GGAAGAATGCAATCCACCGGATCTT 143 527 999 Antisense
CTTACGACTGGCAGTACCGTCATCT 331 213 1037 Antisense
AGTACCGTCATCTTCCTAATGGAAC 122 63 1049 Antisense
Sequence Source Affymetrix Proprietary Database