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[189161_at] Mer5 (mouse)

Description R07E5.2 /REP_DB=WormBase Gene ID /WP=CE00657 /TR=SW:Q21824 /GB=CAA83619.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Mer5 (mouse)
Cluster 6grp_highest_10_10 > 26      6grp_high1_10_10 > 52      4grp_highest_8_8 > 09      4grp_high_8_8 > 61      6grp_highest_nonorm > 27      6grp_total > 62      4grp_total > 58      6grp_highest_sub > 03      6grp_cgc > 73      6grp_high1_sub > 03      6grp_cgc_sub > 02_03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6993
1 2 3 4 range
A 4775.7
(-0.6)
P 		6714.5
(1.2)
P 		8628.6
(3)
P 		2268.8
(-3)
P 		6360
B 4358
(-0.7)
P 		6860
(2)
P 		7781.3
(3)
P 		2222.7
(-3)
P 		5559
C 4361.3
(-0.1)
P 		6892.6
(2.6)
P 		7287.2
(3)
P 		1635.2
(-3)
P 		5652
avr 4498.3
(-0.5) 		6822.4
(1.9) 		7899
(3) 		2042.2
(-3) 		5857

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 5616
1 2 3 4 5 6 range
A 4754.9
(-3)
P 		7383.1
(0.1)
P 		9875.1
(3)
P 		8072.7
(0.9)
P 		6148.1
(-1.4)
P 		5355.6
(-2.3)
P 		5120
B 5671.3
(-1.5)
P 		7625.6
(3)
P 		7310.6
(2.3)
P 		7416.8
(2.5)
P 		6301.7
(-0)
P 		5010.2
(-3)
P 		2615
C 4991
(-2.2)
P 		7680.6
(0.8)
P 		9670.9
(3)
P 		6552.1
(-0.5)
P 		5994.9
(-1.1)
P 		4259.3
(-3)
P 		5412
avr 5139.1
(-2.6) 		7563.1
(1) 		8952.2
(3) 		7347.2
(0.6) 		6148.2
(-1.1) 		4875
(-3) 		4077
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2264
1 2 3 4 range
A 1738.9
(1.4)
P 		1457.5
(0.5)
P 		2255.7
(3)
P 		332.1
(-3)
P 		1924
B 1389.7
(1.1)
P 		1694.2
(2.5)
P 		1803.1
(3)
P 		473.7
(-3)
P 		1329
C 1443.7
(0.1)
P 		1981.7
(1.5)
P 		2539.8
(3)
P 		275.7
(-3)
P 		2264
avr 1524.1
(0.8) 		1711.1
(1.4) 		2199.5
(3) 		360.5
(-3) 		1839

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1749
1 2 3 4 5 6 range
A 876.5
(-3)
P 		2625.8
(3)
P 		2150.6
(1.4)
P 		2047.4
(1)
P 		1855.2
(0.4)
P 		1303.9
(-1.5)
P 		1749
B 1973.3
(-1.5)
P 		2538.2
(2.8)
P 		1775.2
(-3)
P 		1964.4
(-1.6)
P 		2560.3
(3)
P 		1868.3
(-2.3)
P 		785
C 1850
(-0.2)
P 		2343.6
(2.4)
P 		2461.4
(3)
P 		1317.6
(-3)
P 		1939.9
(0.3)
P 		1425.8
(-2.4)
P 		1144
avr 1566.6
(-2.8) 		2502.5
(3) 		2129.1
(0.7) 		1776.5
(-1.5) 		2118.5
(0.6) 		1532.7
(-3) 		970
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189161_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7198
Sequence Type Exemplar sequence
Representative Public ID R07E5.2 NCBI
Target Description R07E5.2 /REP_DB=WormBase Gene ID /WP=CE00657 /TR=SW:Q21824 /GB=CAA83619.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Mer5 (mouse)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065491(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065491 NCBI Caenorhabditis elegans PeRoxireDoXin family member (prdx-3) (prdx-3) mRNA, complete cds. 11/11 None
SNAP00000012850 ENSEMBL cdna:SNAP chromosome:CEL140:III:4407413:4408317:1 11/11 None
GENEFINDER00000012868 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4407413:4408317:1 11/11 None
R07E5.2.2 ENSEMBL cdna:known chromosome:CEL140:III:4407411:4408399:1 gene:R07E5.2 11/11 None
R07E5.2.1 ENSEMBL cdna:known chromosome:CEL140:III:4407413:4408399:1 gene:R07E5.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4407412-4408317(+) 100.0 100.0
Public Domain and Genome References
Gene Title Mer5 (mouse)
Gene Symbol prdx-3
Ensembl R07E5.2
Entrez Gene 175573 Entrez gene
SwissProt Q21824 EMBL-EBI
WormBase CE00657 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1588586_AT similar to Thioredoxin-dependent peroxide reductase, mitochondrial precursor (Peroxiredoxin 3) (Antioxidant protein 1) (AOP-1) (MER5 protein homolog) (HBC189) (PRX III) cfa
CANINE_2:CFA.19049.1.S1_AT similar to Thioredoxin-dependent peroxide reductase, mitochondrial precursor (Peroxiredoxin 3) (Antioxidant protein 1) (AOP-1) (MER5 protein homolog) (HBC189) (PRX III) cfa
CANINE_2:CFAAFFX.8419.1.S1_S_AT similar to Thioredoxin-dependent peroxide reductase, mitochondrial precursor (Peroxiredoxin 3) (Antioxidant protein 1) (AOP-1) (MER5 protein homolog) (HBC189) (PRX III) cfa
CANINE_2:CFAAFFX.9242.1.S1_AT similar to Thioredoxin-dependent peroxide reductase, mitochondrial precursor (Peroxiredoxin 3) (Antioxidant protein 1) (AOP-1) (MER5 protein homolog) (HBC189) (PRX III) cfa
DROSOPHILA_2:1641195_AT Peroxiredoxin 5037 dm
DROSGENOME1:141746_AT Peroxiredoxin 5037 dm
CHICKEN:GGA.4515.3.S1_A_AT similar to Thioredoxin-dependent peroxide reductase, mitochondrial precursor (Peroxiredoxin 3) (Antioxidant protein 1) (AOP-1) (MER5 protein homolog) (HBC189) (PRX III) gga
HG-U133A:201619_AT peroxiredoxin 3 hs
HG-U133_PLUS_2:201619_AT peroxiredoxin 3 hs
HG-FOCUS:201619_AT peroxiredoxin 3 hs
HG-U133A_2:201619_AT peroxiredoxin 3 hs
HG-U133A:209766_AT peroxiredoxin 3 hs
HG-U133_PLUS_2:209766_AT peroxiredoxin 3 hs
HG-U133A_2:209766_AT peroxiredoxin 3 hs
HUGENEFL:D49396_AT peroxiredoxin 3 hs
U133_X3P:G6650791_RC_3P_AT peroxiredoxin 3 hs
U133_X3P:G5802973_3P_AT peroxiredoxin 3 hs
HG-U95AV2:36631_AT peroxiredoxin 3 hs
HG-U95D:73485_AT Peroxiredoxin 3 hs
MU11KSUBA:M28723_S_AT peroxiredoxin 3 mm
MG-U74AV2:96256_AT peroxiredoxin 3 mm
MOE430A:1416292_AT peroxiredoxin 3 mm
MOUSE430A_2:1416292_AT peroxiredoxin 3 mm
MOUSE430_2:1416292_AT peroxiredoxin 3 mm
RG-U34A:RC_AA799650_AT peroxiredoxin 3 rn
RG-U34A:RC_AA799650_G_AT peroxiredoxin 3 rn
RAE230A:1367591_AT peroxiredoxin 3 rn
RAT230_2:1367591_AT peroxiredoxin 3 rn
RAE230B:1390950_AT Peroxiredoxin 3 rn
RAT230_2:1390950_AT Peroxiredoxin 3 rn
RAE230B:1397269_AT Peroxiredoxin 3 rn
RAT230_2:1397269_AT Peroxiredoxin 3 rn
RG-U34C:RC_AI234865_AT Peroxiredoxin 3 rn
Protein Similarities
Method ID Description E-Value
blast CAA83619 Hypothetical protein R07E5.2 [Caenorhabditis elegans] ref|NP_497892.1| PeRoxireDoXin family member (prdx-3) [Caenorhabditis elegans] sp|Q21824|TDX1_CAEEL Probable peroxiredoxin (Thioredoxin peroxidase) (Thioredoxin-dependent peroxide reductase) (Thiol-specific antioxidant protein) 1.0E-130
blast CAE71210 Hypothetical protein CBG18073 [Caenorhabditis briggsae] 1.0E-122
Protein Domains
Database ID Description E-Value
Pfam IPR000866 EMBL-EBI Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 1.6E-71
Sequence
Target Sequence 
>C. ELEGANS:189161_AT
agcacatctcgtgctcttttgtcacttcgtccacttggaccaaaaaatactgtcccagct
ttcaaaggaactgctgtcgttgatggagacttcaaggtgatttctgatcaagactacaaa
ggaaaatggctcgtcatgttcttctatccacttgacttcacctttgtatgcccaactgaa
atcatcgcatacggagatcgtgcaaacgagttccgttctcttggagctgaagttgtcgcg
tgctcgtgtgattctcacttctctcacttggcctgggttaacactccacgcaaggacgga
ggactcggtgatatggacatccctttgctcgctgatttcaacaagaagatcgccgactcg
ttcggtgtgctcgacaaggaatccggactctcataccgtggacttttcctcattgatcca
tctggaactgtccgtcacactacttgtaacgatcttccagttggaagatctgttgatgag
actttgagagtgctcaaggcattccaattctctga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGCACATCTCGTGCTCTTTTGTCAC 137 77 76 Antisense
AAATGGCTCGTCATGTTCTTCTATC 487 121 199 Antisense
TATCCACTTGACTTCACCTTTGTAT 484 657 220 Antisense
AAACGAGTTCCGTTCTCTTGGAGCT 701 125 279 Antisense
TCTCTCACTTGGCCTGGGTTAACAC 233 611 335 Antisense
CCCTTTGCTCGCTGATTTCAACAAG 532 259 396 Antisense
AGAAGATCGCCGACTCGTTCGGTGT 317 73 419 Antisense
GACAAGGAATCCGGACTCTCATACC 68 365 448 Antisense
CATACCGTGGACTTTTCCTCATTGA 252 215 467 Antisense
TGATCCATCTGGAACTGTCCGTCAC 483 565 489 Antisense
TGCTCAAGGCATTCCAATTCTCTGA 255 581 566 Antisense
Sequence Source Affymetrix Proprietary Database