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[189145_at] distal-less homeotic protein

Description ZK652.5 /REP_DB=WormBase Gene ID /WP=CE00451 /GEN=ceh-23 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=distal-less homeotic protein
Cluster 6grp_total > 12      4grp_total > 22      6grp_cgc > 43      6grp_cgc_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 117.2
(3)
A 		24.1
(-2.9)
A 		22.7
(-3)
A 		117.9
(3)
A 		95
B 91.9
(2.7)
A 		48.9
(-0.6)
A 		18.5
(-3)
A 		95.7
(3)
A 		77
C 128.4
(3)
A 		69
(-1.7)
A 		51.8
(-3)
A 		85.4
(-0.4)
A 		77
avr 112.5
(3) 		47.3
(-1.8) 		31
(-3) 		99.7
(2.1) 		82

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 188
1 2 3 4 5 6 range
A 87.9
(-1.8)
A 		215.9
(3)
P 		67.2
(-2.6)
A 		55.9
(-3)
A 		90.1
(-1.7)
A 		78.3
(-2.2)
A 		160
B 164.2
(0.8)
P 		229.2
(3)
P 		111.9
(-1)
A 		118.3
(-0.8)
A 		78.9
(-2.1)
A 		53.7
(-3)
A 		176
C 181.1
(0.9)
P 		241.2
(3)
P 		148.4
(-0.2)
A 		132.3
(-0.8)
A 		72.3
(-2.8)
A 		67.5
(-3)
A 		174
avr 144.4
(-0.1) 		228.8
(3) 		109.2
(-1.4) 		102.2
(-1.7) 		80.4
(-2.5) 		66.5
(-3) 		162
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 42.7
(3)
A 		5.2
(-3)
A 		5.9
(-2.9)
A 		17.3
(-1.1)
A 		38
B 29.3
(3)
A 		12.1
(-1.1)
A 		4.3
(-3)
A 		20.4
(0.9)
A 		25
C 42.5
(3)
A 		19.8
(-1.8)
A 		18.1
(-2.2)
A 		14.4
(-3)
A 		28
avr 38.2
(3) 		12.4
(-2.4) 		9.4
(-3) 		17.4
(-1.3) 		29

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 63
1 2 3 4 5 6 range
A 16.2
(-2.8)
A 		76.8
(3)
P 		14.6
(-3)
A 		14.2
(-3)
A 		27.2
(-1.8)
A 		19.1
(-2.5)
A 		63
B 57.1
(1)
P 		76.3
(3)
P 		27.2
(-2.2)
A 		31.3
(-1.8)
A 		32.1
(-1.7)
A 		20
(-3)
A 		56
C 67.1
(2.2)
P 		73.6
(3)
P 		37.8
(-1.2)
A 		26.6
(-2.5)
A 		23.4
(-2.9)
A 		22.6
(-3)
A 		51
avr 46.8
(-0.1) 		75.6
(3) 		26.5
(-2.4) 		24
(-2.6) 		27.6
(-2.2) 		20.6
(-3) 		55
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189145_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7262
Sequence Type Exemplar sequence
Representative Public ID ZK652.5 NCBI
Target Description ZK652.5 /REP_DB=WormBase Gene ID /WP=CE00451 /GEN=ceh-23 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=distal-less homeotic protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066299(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066299 NCBI Caenorhabditis elegans C.Elegans Homeobox family member (ceh-23) (ceh-23) mRNA, complete cds. 11/11 None
SNAP00000029624 ENSEMBL cdna:SNAP chromosome:CEL140:III:7839516:7841289:1 11/11 None
GENEFINDER00000029641 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:7839516:7841678:1 10/11 None
ZK652.5 ENSEMBL cdna:known chromosome:CEL140:III:7839516:7841413:1 gene:ZK652.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7839513-7841287(+) 91.61 100.0
Public Domain and Genome References
Gene Title distal-less homeotic protein
Gene Symbol ceh-23
Ensembl ZK652.5
Entrez Gene 176096 Entrez gene
SwissProt P34663 EMBL-EBI
WormBase CE00451 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA28218 C.elegans homeobox protein 23 [Caenorhabditis elegans] ref|NP_498700.1| C.Elegans Homeobox family member (ceh-23) [Caenorhabditis elegans] sp|P34663|HM23_CAEEL Homeobox protein ceh-23 1.0E-138
blast AAC37167 homeobox protein 1.0E-137
blast AAA28218 C.elegans homeobox protein 23 [Caenorhabditis elegans] ref|NP_498700.1| C.Elegans Homeobox family member (ceh-23) [Caenorhabditis elegans] sp|P34663|HM23_CAEEL Homeobox protein ceh-23 1.0E-130
blast AAC37167 homeobox protein 1.0E-129
blast CAE66864 Hypothetical protein CBG12238 [Caenorhabditis briggsae] 1.0E-71
Protein Domains
Database ID Description E-Value
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 7.99999985961336E-13
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 4.99999984132761E-21
Pfam IPR001356 EMBL-EBI Homeobox 7.9E-27
Pfam IPR001356 EMBL-EBI Homeobox 8.4E-13
Sequence
Target Sequence 
>C. ELEGANS:189145_AT
gctgtcgaagctcttgcaaatgcactttttgcaacaacaagccgtcgggcttcttgccca
gaacctcctgcatcctctcaagcaaccgtcacgcttcaagtcccatctacgggttctcca
gaacgacgacgttattcagaaacaaatatggaggttctgctacgtgaacaacttgcacaa
ttgatgcctccaacctctcaactacccggaatgcctggatgttattatcaacatgttcca
gctgctggaacttcaggaattcaaggatcattagatgcggcgttaatgggagctgttccc
ttggctatgaatagtatggcacatagtcggagagcagcaaatcatagaaaagcaagaaca
atctacggtacaacacaaactcaacaactggaagatatgtttaaaggacaaatgtacgta
gtcggagcagaacgagaaaatcttgctcaacgccttggcctatcaccttctcaagttaga
a

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTGTCGAAGCTCTTGCAAATGCAC 257 295 301 Antisense
ACAACAAGCCGTCGGGCTTCTTGCC 212 113 334 Antisense
CTCAAGCAACCGTCACGCTTCAAGT 28 229 377 Antisense
CTTCAAGTCCCATCTACGGGTTCTC 649 195 394 Antisense
GGGTTCTCCAGAACGACGACGTTAT 195 495 411 Antisense
CTTGCACAATTGATGCCTCCAACCT 356 219 472 Antisense
TCTCAACTACCCGGAATGCCTGGAT 456 613 496 Antisense
ATTATCAACATGTTCCAGCTGCTGG 408 13 524 Antisense
GATGCGGCGTTAATGGGAGCTGTTC 690 413 574 Antisense
AGCTGTTCCCTTGGCTATGAATAGT 330 81 591 Antisense
GGCCTATCACCTTCTCAAGTTAGAA 676 541 757 Antisense
Sequence Source Affymetrix Proprietary Database