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[189128_s_at] SNAP-25 family

Description Y22F5A.3 /REP_DB=WormBase Gene ID /WP=CE16604 /TR=O62414 /GB=CAA16322.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=SNAP-25 family
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 02      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 21      6grp_total > 24      4grp_total > 20      6grp_highest_sub > De      6grp_cgc > 34      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1902
1 2 3 4 range
A 1770.1
(-0.3)
P 		1377.9
(-1.5)
P 		917.8
(-3)
P 		2819.6
(3)
P 		1902
B 1981.3
(0.3)
P 		1667.9
(-0.8)
P 		1017.7
(-3)
P 		2767.7
(3)
P 		1750
C 2110.8
(1.7)
P 		1748.5
(-0.3)
P 		1271.7
(-3)
P 		2335.5
(3)
P 		1064
avr 1954.1
(0.4) 		1598.1
(-1) 		1069.1
(-3) 		2640.9
(3) 		1572

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 833
1 2 3 4 5 6 range
A 1224
(-0.1)
P 		1638.6
(3)
P 		1627.4
(2.9)
P 		1392
(1.2)
P 		830.3
(-3)
P 		907.5
(-2.4)
P 		808
B 1634.5
(3)
P 		1514.4
(1.8)
P 		1429.9
(0.9)
P 		1042.5
(-3)
P 		1060.4
(-2.8)
P 		1142.9
(-2)
P 		592
C 1662.8
(3)
P 		1532.8
(2.1)
P 		1257.2
(0)
P 		1211.7
(-0.3)
P 		838
(-3)
P 		1197.7
(-0.4)
P 		825
avr 1507.1
(2.5) 		1561.9
(3) 		1438.2
(1.9) 		1215.4
(-0.2) 		909.6
(-3) 		1082.7
(-1.4) 		652
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 463
1 2 3 4 range
A 644.5
(3)
P 		299.1
(-2.1)
P 		239.9
(-3)
P 		412.7
(-0.4)
P 		405
B 631.8
(3)
P 		411.9
(-0.3)
P 		235.8
(-3)
P 		589.8
(2.4)
P 		396
C 698.7
(3)
P 		502.7
(-0.9)
P 		443.2
(-2)
P 		393.8
(-3)
P 		305
avr 658.3
(3) 		404.6
(-1.3) 		306.3
(-3) 		465.4
(-0.3) 		352

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 395
1 2 3 4 5 6 range
A 225.6
(-2.9)
P 		582.8
(3)
P 		354.4
(-0.8)
P 		353
(-0.8)
P 		250.6
(-2.5)
P 		220.9
(-3)
P 		362
B 568.7
(3)
P 		504.1
(1.7)
P 		347.2
(-1.5)
P 		276.1
(-3)
P 		430.8
(0.2)
P 		426.2
(0.1)
P 		293
C 616.3
(3)
P 		467.7
(0.6)
P 		320
(-1.8)
P 		243.7
(-3)
P 		271.2
(-2.6)
P 		400.9
(-0.5)
P 		373
avr 470.2
(1.7) 		518.2
(3) 		340.5
(-1.7) 		290.9
(-3) 		317.5
(-2.3) 		349.3
(-1.5) 		227
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 189128_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12495
Sequence Type Exemplar sequence
Representative Public ID Y22F5A.3 NCBI
Target Description Y22F5A.3 /REP_DB=WormBase Gene ID /WP=CE16604 /TR=O62414 /GB=CAA16322.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=SNAP-25 family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073240(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073240 NCBI Caenorhabditis elegans Resistance to Inhibitors of Cholinesterase family member (ric-4) (ric-4) mRNA, complete cds. 10/11 None
SNAP00000026002 ENSEMBL cdna:SNAP chromosome:CEL140:V:10264064:10265244:-1 11/11 None
GENEFINDER00000026010 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:10264064:10265244:-1 11/11 None
Y22F5A.3 ENSEMBL cdna:known chromosome:CEL140:V:10263713:10272895:-1 gene:Y22F5A.3 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10264063-10265244(-) 100.0 100.0
Public Domain and Genome References
Gene Title SNAP-25 family
Gene Symbol ric-4
Ensembl Y22F5A.3
Entrez Gene 179427 Entrez gene
SwissProt O62414 EMBL-EBI
WormBase CE32008 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1604613_AT similar to Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23) (Syndet) cfa
CANINE_2:CFA.18926.1.S1_AT similar to Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23) (Syndet) cfa
CANINE_2:CFAAFFX.17344.1.S1_S_AT similar to Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23) (Syndet) cfa
HG-U133_PLUS_2:209130_AT synaptosomal-associated protein, 23kDa hs
HG-U133A:209130_AT synaptosomal-associated protein, 23kDa hs
HG-FOCUS:209130_AT synaptosomal-associated protein, 23kDa hs
HG-U133A_2:209130_AT synaptosomal-associated protein, 23kDa hs
HG-U133_PLUS_2:209131_S_AT synaptosomal-associated protein, 23kDa hs
HG-U133A:209131_S_AT synaptosomal-associated protein, 23kDa hs
HG-U133A_2:209131_S_AT synaptosomal-associated protein, 23kDa hs
HU35KSUBB:RC_N25249_AT synaptosomal-associated protein, 23kDa hs
HU35KSUBD:RC_AA342059_S_AT synaptosomal-associated protein, 23kDa hs
HUGENEFL:U55936_AT synaptosomal-associated protein, 23kDa hs
HG-U133_PLUS_2:214544_S_AT synaptosomal-associated protein, 23kDa hs
HG-U133A_2:214544_S_AT synaptosomal-associated protein, 23kDa hs
HG-U133A:214544_S_AT synaptosomal-associated protein, 23kDa hs
U133_X3P:G1374812_3P_A_AT synaptosomal-associated protein, 23kDa hs
U133_X3P:G13277555_3P_AT synaptosomal-associated protein, 23kDa hs
HG-U95AV2:32179_S_AT synaptosomal-associated protein, 23kDa hs
HG-U95AV2:32178_R_AT synaptosomal-associated protein, 23kDa hs
HG-U95B:46749_I_AT synaptosomal-associated protein, 23kDa hs
HG-U95B:42622_AT Synaptosomal-associated protein, 23kDa hs
HG-U95E:88736_AT Synaptosomal-associated protein, 23kDa hs
HU35KSUBB:RC_H02552_AT Synaptosomal-associated protein, 23kDa hs
MU11KSUBA:AB000822_AT synaptosomal-associated protein 23 mm
MU11KSUBA:AB000822_G_AT synaptosomal-associated protein 23 mm
MU11KSUBA:AA125580_AT synaptosomal-associated protein 23 mm
MOE430A:1420896_AT synaptosomal-associated protein 23 mm
MOUSE430A_2:1420896_AT synaptosomal-associated protein 23 mm
MOUSE430_2:1420896_AT synaptosomal-associated protein 23 mm
MOE430A:1420897_AT synaptosomal-associated protein 23 mm
MOUSE430A_2:1420897_AT synaptosomal-associated protein 23 mm
MOUSE430_2:1420897_AT synaptosomal-associated protein 23 mm
MOE430A:1420898_AT synaptosomal-associated protein 23 mm
MOUSE430A_2:1420898_AT synaptosomal-associated protein 23 mm
MOUSE430_2:1420898_AT synaptosomal-associated protein 23 mm
MG-U74AV2:96945_AT synaptosomal-associated protein 23 mm
MU19KSUBB:TC30921_AT Synaptosomal-associated protein 23 (Snap23), mRNA mm
MU19KSUBB:TC30921_G_AT Synaptosomal-associated protein 23 (Snap23), mRNA mm
Protein Similarities
Method ID Description E-Value
blast CAE64778 Hypothetical protein CBG09569 [Caenorhabditis briggsae] 1.0E-129
blast CAE64778 Hypothetical protein CBG09569 [Caenorhabditis briggsae] 1.0E-127
blast CAA16322 Hypothetical protein Y22F5A.3 [Caenorhabditis elegans] ref|NP_505641.2| Resistance to Inhibitors of Cholinesterase family member (ric-4) [Caenorhabditis elegans] 1.0E-116
blast CAA16322 Hypothetical protein Y22F5A.3 [Caenorhabditis elegans] ref|NP_505641.2| Resistance to Inhibitors of Cholinesterase family member (ric-4) [Caenorhabditis elegans] 1.0E-104
blast CAA16322 Hypothetical protein Y22F5A.3 [Caenorhabditis elegans] ref|NP_505641.2| Resistance to Inhibitors of Cholinesterase family member (ric-4) [Caenorhabditis elegans] 1.0E-102
blast CAE64778 Hypothetical protein CBG09569 [Caenorhabditis briggsae] 1.0E-101
blast AAM18191 SNAP25 fusion protein [Loligo pealei] 1.0E-70
Protein Domains
Database ID Description E-Value
Pfam IPR000928 EMBL-EBI SNAP-25 1.8E-25
Pfam IPR000727 EMBL-EBI Target SNARE coiled-coil domain 1.8E-18
Pfam IPR000928 EMBL-EBI SNAP-25 1.8E-25
Pfam IPR000727 EMBL-EBI Target SNARE coiled-coil domain 1.8E-18
Pfam IPR000928 EMBL-EBI SNAP-25 1.8E-25
Pfam IPR000727 EMBL-EBI Target SNARE coiled-coil domain 1.8E-18
Sequence
Target Sequence 
>C. ELEGANS:189128_S_AT
atgggttggtacttccagctgatatgagtgatgagcttaaagggcttaatgtgggaattg
atgaaaagactatagagtcattggaatccaccagaagaatgttggctctttgcgaagaaa
gtaaagaggctggaatcaaaactttggttatgctcgatgatcaaggagaacaacttgagc
gttgcgaaggtgctcttgatacaatcaatcaggacatgaaagaagcagaagatcatttga
aaggaatggaaaaatgttgtggtttgtgtgtattgccatggaacaagaccgatgactttg
aaaagacggaatttgcaaaagcatggaagaaagatgatgatggaggtgttatctctgatc
agccaaggatcactgttggagattcatcgatgggacctcaaggaggatatattaccaaga
tcactaatgatgcacgagaagatgaaatggacgagaatgttcaacaagtttcaacaatgg
tcggcaatttgcgtaacatggcaattgatatgagcacagaagtttccaaccagaatagac
aactcgacagaattcatgacaaggctcaatccaacgaagtccgtgtggaatctgctaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGGGTTGGTACTTCCAGCTGATAT 335 49 89 Antisense
AAAACTTTGGTTATGCTCGATGATC 350 131 226 Antisense
GCGTTGCGAAGGTGCTCTTGATACA 502 291 267 Antisense
TGGTTTGTGTGTATTGCCATGGAAC 600 549 348 Antisense
GGAGGTGTTATCTCTGATCAGCCAA 268 517 430 Antisense
GGATCACTGTTGGAGATTCATCGAT 269 511 455 Antisense
GATTCATCGATGGGACCTCAAGGAG 185 429 469 Antisense
TCAACAATGGTCGGCAATTTGCGTA 192 629 559 Antisense
GACAACTCGACAGAATTCATGACAA 674 365 626 Antisense
CAAGGCTCAATCCAACGAAGTCCGT 546 183 648 Antisense
CGAAGTCCGTGTGGAATCTGCTAAC 218 253 663 Antisense
Sequence Source Affymetrix Proprietary Database