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[189119_at] protein kinase

Description K03E5.3 /REP_DB=WormBase Gene ID /WP=CE18009 /TR=O61847 /GB=AAC17568.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 45      4grp_total > 29      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 73
1 2 3 4 range
A 63.8
(1.7)
A 		31.9
(-1.1)
A 		9.9
(-3)
A 		78.4
(3)
A 		69
B 79.9
(3)
A 		42.9
(-0.1)
A 		7.3
(-3)
A 		60.3
(1.4)
A 		73
C 60.2
(3)
A 		54.4
(2.3)
A 		12.6
(-3)
A 		19.1
(-2.2)
A 		48
avr 68
(3) 		43.1
(0.4) 		9.9
(-3) 		52.6
(1.4) 		58

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 20
(3)
A 		14.9
(0.2)
A 		11.5
(-1.6)
A 		8.9
(-3)
A 		14.2
(-0.1)
A 		9.4
(-2.7)
A 		11
B 8.4
(-2.2)
A 		22.6
(3)
A 		6.2
(-3)
A 		9.6
(-1.8)
A 		8
(-2.3)
A 		14.5
(0)
A 		16
C 5.6
(-3)
A 		22.5
(0.1)
A 		38
(3)
A 		8.9
(-2.4)
A 		20.5
(-0.2)
A 		32.7
(2)
A 		32
avr 11.3
(-1.8) 		20
(3) 		18.6
(2.2) 		9.1
(-3) 		14.2
(-0.2) 		18.9
(2.4) 		11
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 24
1 2 3 4 range
A 23.2
(3)
A 		6.9
(-1.7)
A 		2.6
(-3)
A 		11.5
(-0.4)
A 		21
B 25.5
(3)
A 		10.6
(-0.8)
A 		1.7
(-3)
A 		12.9
(-0.2)
A 		24
C 19.9
(3)
A 		15.6
(1.5)
A 		4.4
(-2.6)
A 		3.2
(-3)
A 		17
avr 22.9
(3) 		11
(-0.6) 		2.9
(-3) 		9.2
(-1.1) 		20

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9
1 2 3 4 5 6 range
A 3.7
(-0.2)
A 		5.3
(3)
A 		2.5
(-2.6)
A 		2.3
(-3)
A 		4.3
(1)
A 		2.3
(-3)
A 		3
B 2.9
(-1.6)
A 		7.5
(3)
A 		1.5
(-3)
A 		2.6
(-1.9)
A 		3.3
(-1.2)
A 		5.4
(0.9)
A 		6
C 2.1
(-2.8)
A 		6.9
(0.4)
A 		9.7
(2.2)
A 		1.8
(-3)
A 		6.6
(0.2)
A 		10.9
(3)
A 		9
avr 2.9
(-2) 		6.6
(3) 		4.6
(0.3) 		2.2
(-3) 		4.7
(0.4) 		6.2
(2.5) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189119_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.189
Sequence Type Exemplar sequence
Representative Public ID K03E5.3 NCBI
Target Description K03E5.3 /REP_DB=WormBase Gene ID /WP=CE18009 /TR=O61847 /GB=AAC17568.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026366(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026366 NCBI Caenorhabditis elegans K03E5.3 (K03E5.3) mRNA, complete cds. 11/11 None
K03E5.3a ENSEMBL cdna:known chromosome:CEL140:I:3408034:3415071:1 gene:K03E5.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000035350 8/11 Cross Hyb Matching Probes None
GENEFINDER00000035356 8/11 Cross Hyb Matching Probes None
K03E5.3b 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:3408033-3415071(+) 95.84 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl K03E5.3
Entrez Gene 171911 Entrez gene
SwissProt O61847 EMBL-EBI
WormBase CE36652 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC17568 Hypothetical protein K03E5.3 [Caenorhabditis elegans] ref|NP_001021537.1| K03E5.3 [Caenorhabditis elegans] 0.0
blast CAE68971 Hypothetical protein CBG14952 [Caenorhabditis briggsae] 1.0E-157
blast AAD05577 Cdc2 cyclin-dependent kinase [Pneumocystis carinii f. sp. carinii] 1.0E-86
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 3.0E-84
hanks 3.1.1 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; CDC2Hs 1.0E-87
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 7.7E-88
Sequence
Target Sequence 
>C. ELEGANS:189119_AT
gtcatctccgacggattgttcaccgtgatctgaagcctcagaatattctggtttcagatt
ctggagtcatcaaaattgcggatttcggattggcaagaaatttctcgttccccagtcgaa
actatactcacgaggtggtaactctttggtatcgtccgccagagattctgctcggctcgc
aacgttattcaacatcactggatatgtggtcgctgggatgtatattctccgaaattgcat
cgaataagcctctgtttccaggcgaatgcgagatttcacagctattcaagatatttgaaa
ttgttggaacaccaaatattaagagctggccaggcgtcgactcgtttccccactacaagg
cagtctttccacagtggccggtgaatttgaagaagctcgaagaaacatcatgcctgactg
gaaatggtcttgacgtgcttcgtgagatacttcgttatccaccggagcgacgtctcaccg
cgaaaggtgctctctctcatcgctactttctacagaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCATCTCCGACGGATTGTTCACCG 474 467 542 Antisense
TGGCAAGAAATTTCTCGTTCCCCAG 295 543 632 Antisense
GTTCCCCAGTCGAAACTATACTCAC 552 441 648 Antisense
GTGGTAACTCTTTGGTATCGTCCGC 602 475 676 Antisense
CTCGGCTCGCAACGTTATTCAACAT 407 231 712 Antisense
GCATCGAATAAGCCTCTGTTTCCAG 707 307 778 Antisense
TTAAGAGCTGGCCAGGCGTCGACTC 161 683 860 Antisense
ACAAGGCAGTCTTTCCACAGTGGCC 489 113 896 Antisense
GAAATGGTCTTGACGTGCTTCGTGA 312 361 962 Antisense
GTGAGATACTTCGTTATCCACCGGA 622 483 983 Antisense
TCTCTCATCGCTACTTTCTACAGAA 219 613 1034 Antisense
Sequence Source Affymetrix Proprietary Database