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[189118_at] protein kinase

Description T17A3.1 /REP_DB=WormBase Gene ID /WP=CE19579 /TR=O76698 /GB=AAC26948.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 43      4grp_total > 02      6grp_cgc > 91      6grp_cgc_sub > 03      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 33
1 2 3 4 range
A 3.8
(-2.3)
A 		5.3
(-1.6)
A 		2.2
(-3)
A 		15.8
(3)
A 		14
B 4.4
(-2.7)
A 		3.6
(-2.8)
A 		2.9
(-3)
A 		29.2
(3)
A 		26
C 5.7
(-2.3)
A 		4.4
(-2.5)
A 		1.9
(-3)
A 		34.7
(3)
A 		33
avr 4.6
(-2.4) 		4.4
(-2.5) 		2.3
(-3) 		26.6
(3) 		24

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 15
1 2 3 4 5 6 range
A 4.4
(-1.9)
A 		4.3
(-1.9)
A 		16.5
(3)
A 		1.7
(-3)
A 		4.2
(-2)
A 		1.9
(-2.9)
A 		15
B 6
(3)
A 		5
(1.3)
A 		2.6
(-2.8)
A 		3.5
(-1.3)
A 		2.5
(-3)
A 		2.8
(-2.5)
A 		4
C 5.2
(-1.8)
A 		4.7
(-2)
A 		15.5
(3)
A 		2.5
(-3)
A 		3.3
(-2.6)
A 		2.9
(-2.8)
A 		13
avr 5.2
(-1.2) 		4.7
(-1.5) 		11.5
(3) 		2.6
(-2.9) 		3.3
(-2.5) 		2.5
(-3) 		9
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6
1 2 3 4 range
A 1.4
(-0.2)
A 		1.1
(-1.2)
A 		0.6
(-3)
A 		2.3
(3)
A 		2
B 1.4
(-2.2)
A 		0.9
(-2.8)
A 		0.7
(-3)
A 		6.2
(3)
A 		6
C 1.9
(-1.6)
A 		1.3
(-2.3)
A 		0.7
(-3)
A 		5.9
(3)
A 		5
avr 1.6
(-1.7) 		1.1
(-2.4) 		0.7
(-3) 		4.8
(3) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4
1 2 3 4 5 6 range
A 0.8
(-2.3)
A 		1.5
(-0.9)
A 		3.6
(3)
A 		0.4
(-3)
A 		1.3
(-1.3)
A 		0.5
(-2.8)
A 		3
B 2.1
(3)
A 		1.7
(1.4)
A 		0.6
(-3)
A 		0.9
(-1.8)
A 		1
(-1.4)
A 		1
(-1.4)
A 		2
C 1.9
(-0.5)
A 		1.4
(-1.4)
A 		3.9
(3)
A 		0.5
(-3)
A 		1.1
(-1.9)
A 		1
(-2.1)
A 		3
avr 1.6
(-0.1) 		1.5
(-0.4) 		2.7
(3) 		0.6
(-3) 		1.1
(-1.6) 		0.8
(-2.4) 		2
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189118_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8212
Sequence Type Exemplar sequence
Representative Public ID T17A3.1 NCBI
Target Description T17A3.1 /REP_DB=WormBase Gene ID /WP=CE19579 /TR=O76698 /GB=AAC26948.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064761(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064761 NCBI Caenorhabditis elegans VEGF (vascular endothelial growth factor) Receptor family member (ver-1) (ver-1) mRNA, complete cds. 11/11 A 
SNAP00000008195 ENSEMBL cdna:SNAP chromosome:CEL140:III:157405:160878:1 10/11 None
T17A3.1 ENSEMBL cdna:known chromosome:CEL140:III:156823:163541:1 gene:T17A3.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:156822-160878(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Gene Symbol ver-1
Ensembl T17A3.1
Entrez Gene 175182 Entrez gene
SwissProt O76698 EMBL-EBI
WormBase CE31854 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC26948 Vegf (vascular endothelial growth factor) receptor family protein 1 [Caenorhabditis elegans] ref|NP_497162.2| VEGF (vascular endothelial growth factor) Receptor family member (ver-1) [Caenorhabditis elegans] gb|AAF00548.1| tyrosine kinase receptor T17A3.1 [Caenorhabditis elegans] 0.0
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 0.0
blast CAE70781 Hypothetical protein CBG17536 [Caenorhabditis briggsae] 0.0
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 1.0E-103
blast CAE70781 Hypothetical protein CBG17536 [Caenorhabditis briggsae] 1.0E-102
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-53
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.01
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 8.2E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 8.2E-5
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497162.2 2 13-35,736-758
T17A3.1 2 13-35,736-758
SNAP00000008195 1 587-609
Sequence
Target Sequence 
>C. ELEGANS:189118_AT
tccgacgggctcaaagcttgactgcaacattgatggaagacccccgcccgagtaccaatg
gtttaaggatggcaccccatatggtactgggagacggctgaagttttttgaggaagataa
cagtgggatttatcagtgcctggcaactaatcgtgctggatctgcgactaactcctttga
attgaaaactgctggaagatcttatggaatcttcgtgcttctggcaatactagctctcgg
gatcttagttattttgggttggaagatctccacaaagctgggctggaagaaaaatcgaga
cctgaaacttctctacaaatcgctgattggtagcgaaaactttctaccgaatggaaaaaa
ccaatttagtaattttaactttgaatttcacaaggatagtttagaaattctcgagccaat
tggctccggccactttggagttgtgaggagaggaattttgaagggtacaaagacagtggt
ggctgtgaaaagttcatcataccgcagtagcattgggttccagaaagtgatagtagaaga
gctgaaactaatgagtgctatccctaagcatccgaatgttctggcgctgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCGACGGGCTCAAAGCTTGACTGC 113 595 2019 Antisense
GGATGGCACCCCATATGGTACTGGG 293 513 2085 Antisense
GTGCCTGGCAACTAATCGTGCTGGA 29 479 2154 Antisense
TGGATCTGCGACTAACTCCTTTGAA 148 551 2175 Antisense
TATGGAATCTTCGTGCTTCTGGCAA 311 655 2221 Antisense
CTTCTGGCAATACTAGCTCTCGGGA 63 221 2236 Antisense
GAAGATCTCCACAAAGCTGGGCTGG 40 339 2280 Antisense
GAAACTTCTCTACAAATCGCTGATT 701 355 2322 Antisense
TCTCGAGCCAATTGGCTCCGGCCAC 632 609 2427 Antisense
ATGAGTGCTATCCCTAAGCATCCGA 402 45 2569 Antisense
AAGCATCCGAATGTTCTGGCGCTGG 322 151 2584 Antisense
Sequence Source Affymetrix Proprietary Database