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[189116_at] protein kinase

Description T17A3.8 /REP_DB=WormBase Gene ID /WP=CE19585 /TR=O76695 /GB=AAC26954.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 11      4grp_highest_8_8 > 40      4grp_high_8_8 > 50      6grp_highest_nonorm > 61      6grp_total > 32      4grp_total > 53      6grp_highest_sub > De      6grp_cgc > 60      6grp_high1_sub > De      6grp_total_sub > Hat      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 638
1 2 3 4 range
A 801.4
(3)
P 		640.2
(1.2)
P 		571.9
(0.4)
P 		276.5
(-3)
P 		525
B 857.8
(3)
P 		678.9
(1.3)
P 		605.6
(0.6)
P 		219.5
(-3)
P 		638
C 842.7
(3)
P 		709.8
(1.6)
P 		533.4
(-0.3)
P 		282.8
(-3)
P 		560
avr 834
(3) 		676.3
(1.4) 		570.3
(0.2) 		259.6
(-3) 		574

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 446
1 2 3 4 5 6 range
A 482.6
(0)
P 		601.6
(1.7)
P 		493
(0.2)
P 		690
(3)
P 		432.6
(-0.7)
P 		268.3
(-3)
P 		422
B 537.5
(3)
P 		444.4
(1.1)
P 		416.8
(0.5)
P 		467.9
(1.6)
P 		415.1
(0.5)
P 		244.4
(-3)
P 		293
C 581.6
(2)
P 		516.1
(1)
P 		650.7
(3)
P 		344.1
(-1.6)
P 		396
(-0.8)
P 		253
(-3)
P 		398
avr 533.9
(3) 		520.7
(2.7) 		520.2
(2.7) 		500.7
(2.3) 		414.6
(0.4) 		255.2
(-3) 		279
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 251
1 2 3 4 range
A 291.8
(3)
P 		139
(-0.6)
P 		149.5
(-0.4)
P 		40.5
(-3)
P 		251
B 273.6
(3)
P 		167.7
(0.2)
P 		140.3
(-0.5)
P 		46.8
(-3)
P 		227
C 279
(3)
P 		204.1
(1.1)
P 		185.9
(0.6)
P 		47.7
(-3)
P 		231
avr 281.5
(3) 		170.3
(0.2) 		158.6
(-0.1) 		45
(-3) 		237

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 150
1 2 3 4 5 6 range
A 89
(-2)
P 		214
(3)
P 		107.4
(-1.3)
P 		175
(1.4)
P 		130.5
(-0.4)
P 		65.3
(-3)
P 		149
B 187
(3)
P 		147.9
(0.6)
P 		101.2
(-2.4)
P 		123.9
(-0.9)
P 		168.6
(1.8)
P 		91.1
(-3)
P 		96
C 215.6
(3)
P 		157.5
(0.6)
P 		165.6
(1)
P 		69.2
(-3)
P 		128.1
(-0.6)
P 		84.7
(-2.4)
P 		146
avr 163.9
(2.4) 		173.1
(3) 		124.7
(-0.1) 		122.7
(-0.3) 		142.4
(1) 		80.4
(-3) 		93
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189116_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8176
Sequence Type Exemplar sequence
Representative Public ID T17A3.8 NCBI
Target Description T17A3.8 /REP_DB=WormBase Gene ID /WP=CE19585 /TR=O76695 /GB=AAC26954.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064757(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064757 NCBI Caenorhabditis elegans VEGF (vascular endothelial growth factor) Receptor family member (ver-2) (ver-2) mRNA, complete cds. 11/11 None
GENEFINDER00000008197 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:139643:153417:-1 9/11 None
SNAP00000008188 ENSEMBL cdna:SNAP chromosome:CEL140:III:145543:147606:-1 9/11 None
T17A3.8 ENSEMBL cdna:known chromosome:CEL140:III:146982:150175:-1 gene:T17A3.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:146981-150196(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Gene Symbol ver-2
Ensembl T17A3.8
Entrez Gene 188569 Entrez gene
SwissProt O76695 EMBL-EBI
WormBase CE31609 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC26954 Vegf (vascular endothelial growth factor) receptor family protein 2 [Caenorhabditis elegans] ref|NP_497158.2| VEGF (vascular endothelial growth factor) Receptor family member (ver-2) [Caenorhabditis elegans] 0.0
blast AAC26950 Hypothetical protein T17A3.3 [Caenorhabditis elegans] ref|NP_497154.1| T17A3.3 [Caenorhabditis elegans] 0.0
blast AAC26951 Hypothetical protein T17A3.4 [Caenorhabditis elegans] ref|NP_497155.1| T17A3.4 [Caenorhabditis elegans] 0.0
blast AAC26953 Hypothetical protein T17A3.7 [Caenorhabditis elegans] ref|NP_497157.1| T17A3.7 [Caenorhabditis elegans] 1.0E-164
blast AAC26951 Hypothetical protein T17A3.4 [Caenorhabditis elegans] ref|NP_497155.1| T17A3.4 [Caenorhabditis elegans] 1.0E-122
blast AAC26950 Hypothetical protein T17A3.3 [Caenorhabditis elegans] ref|NP_497154.1| T17A3.3 [Caenorhabditis elegans] 1.0E-111
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 2.0E-82
Protein Domains
Database ID Description E-Value
Pfam IPR000433 EMBL-EBI Zn-finger, ZZ type 1.7E-11
Pfam IPR000719 EMBL-EBI Protein kinase 0.12
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-40
Pfam IPR000433 EMBL-EBI Zn-finger, ZZ type 2.6E-7
Pfam IPR001810 EMBL-EBI Cyclin-like F-box 1.1E-6
Pfam IPR001810 EMBL-EBI Cyclin-like F-box 2.5E-5
Pfam IPR001810 EMBL-EBI Cyclin-like F-box 1.2E-7
Pfam IPR000719 EMBL-EBI Protein kinase 9.6E-52
Pfam IPR001810 EMBL-EBI Cyclin-like F-box 1.1E-6
Pfam IPR000433 EMBL-EBI Zn-finger, ZZ type 2.6E-7
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000008197 1 298-320
Sequence
Target Sequence 
>C. ELEGANS:189116_AT
gagtttattccacaagagcgacgtctcgatgttctggttaacgcccagaaaacaatttgt
gaaactaaagaaaagaaagggcggatagtttttgtgacattcgccacaaaattcgacaaa
aaagtggttgaaattaccttagatgaagaggacccgctgagccagttgtacaaaacagcc
caggaaatttttccttacttctcatggcggttttgtcttgatgagccaaccaatctcatt
gaaggcttgtcaaacaaacgccgagtttttggtagtatcaagcaatcccgtttctacaac
tttctctatcttgtcatcactctcttaccgacttatcatccattcgactgtgacgagtgc
aaggcagaatgcaactggaataatcgatacaaatgcacaatatgcgccgattatgacctt
tgtaggcagtgtgaggcaaaaaacttgcacgcaaatcatgcaatgcttaggattctctct
agtgataccgaact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGTTTATTCCACAAGAGCGACGTC 90 397 1411 Antisense
AGAGCGACGTCTCGATGTTCTGGTT 385 69 1425 Antisense
GGATAGTTTTTGTGACATTCGCCAC 530 509 1493 Antisense
GACCCGCTGAGCCAGTTGTACAAAA 597 381 1561 Antisense
GGCGGTTTTGTCTTGATGAGCCAAC 289 541 1616 Antisense
TATCAAGCAATCCCGTTTCTACAAC 408 659 1686 Antisense
ACAACTTTCTCTATCTTGTCATCAC 406 113 1706 Antisense
ACCGACTTATCATCCATTCGACTGT 329 85 1737 Antisense
TATGCGCCGATTATGACCTTTGTAG 357 657 1811 Antisense
TCATGCAATGCTTAGGATTCTCTCT 200 623 1866 Antisense
GGATTCTCTCTAGTGATACCGAACT 455 509 1880 Antisense
Sequence Source Affymetrix Proprietary Database