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[189102_at] protein kinase

Description C18H7.4 /REP_DB=WormBase Gene ID /WP=CE17429 /TR=Q9GZG1 /GB=AAF98610.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster 6grp_total > 98      4grp_total > 27      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 22
1 2 3 4 range
A 15.6
(1)
A 		19.1
(3)
A 		8.8
(-3)
A 		16.3
(1.4)
A 		10
B 8.2
(3)
A 		6.7
(1.2)
A 		3.2
(-3)
A 		3.5
(-2.6)
A 		5
C 5.1
(-3)
A 		14.3
(-0.2)
A 		8.7
(-1.9)
A 		24.7
(3)
A 		20
avr 9.6
(-0.9) 		13.4
(1.9) 		6.9
(-3) 		14.8
(3) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 144
1 2 3 4 5 6 range
A 3.8
(-3)
A 		14.2
(-2.5)
A 		10.6
(-2.7)
A 		34.5
(-1.4)
A 		74.5
(0.6)
A 		120.9
(3)
P 		117
B 3.9
(-2.9)
A 		3.5
(-3)
A 		38.3
(-1.5)
A 		2.4
(-3)
A 		97.3
(1)
M 		146
(3)
P 		144
C 8.3
(-2.7)
A 		14.9
(-2.3)
A 		18
(-2.1)
A 		3.6
(-3)
A 		67.5
(1)
A 		98.5
(3)
P 		95
avr 5.3
(-3) 		10.9
(-2.7) 		22.3
(-2.1) 		13.5
(-2.6) 		79.8
(0.8) 		121.8
(3) 		117
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5
1 2 3 4 range
A 5.7
(3)
A 		4.1
(0.2)
A 		2.3
(-3)
A 		2.4
(-2.8)
A 		3
B 2.6
(3)
A 		1.7
(0.2)
A 		0.7
(-3)
A 		0.7
(-3)
A 		2
C 1.7
(-3)
A 		4.1
(2.8)
A 		3
(0.1)
A 		4.2
(3)
A 		3
avr 3.3
(3) 		3.3
(3) 		2
(-3) 		2.4
(-1.2) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 54
1 2 3 4 5 6 range
A 0.7
(-3)
A 		5.1
(-2.1)
A 		2.3
(-2.7)
A 		8.7
(-1.3)
A 		22.5
(1.6)
A 		29.4
(3)
P 		29
B 1.3
(-2.9)
A 		1.2
(-2.9)
A 		9.3
(-2)
A 		0.6
(-3)
A 		39.5
(1.3)
M 		54.4
(3)
P 		54
C 3.1
(-2.6)
A 		4.5
(-2.3)
A 		4.6
(-2.3)
A 		0.7
(-3)
A 		21.9
(0.9)
A 		33
(3)
P 		32
avr 1.7
(-3) 		3.6
(-2.7) 		5.4
(-2.4) 		3.3
(-2.7) 		28
(1.2) 		38.9
(3) 		37
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189102_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10399
Sequence Type Exemplar sequence
Representative Public ID C18H7.4 NCBI
Target Description C18H7.4 /REP_DB=WormBase Gene ID /WP=CE17429 /TR=Q9GZG1 /GB=AAF98610.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067552(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067552 NCBI Caenorhabditis elegans C18H7.4 (C18H7.4) mRNA, complete cds. 11/11 None
SNAP00000042862 ENSEMBL cdna:SNAP chromosome:CEL140:IV:593477:595167:1 11/11 None
GENEFINDER00000042881 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:593477:595127:1 11/11 None
C18H7.4 ENSEMBL cdna:known chromosome:CEL140:IV:592485:595167:1 gene:C18H7.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:592490-595173(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
Ensembl C18H7.4
Entrez Gene 182803 Entrez gene
SwissProt Q9GZG1 EMBL-EBI
WormBase CE17429 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF98610 Hypothetical protein C18H7.4 [Caenorhabditis elegans] ref|NP_499953.1| C18H7.4 [Caenorhabditis elegans] 0.0
blast CAE59293 Hypothetical protein CBG02628 [Caenorhabditis briggsae] 0.0
blast CAA88727 Hypothetical protein R05H5.4 [Caenorhabditis elegans] ref|NP_496201.1| R05H5.4 [Caenorhabditis elegans] 1.0E-162
Protein Families
Method ID Description E-Value
hanks 2.1.6 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; CamKI 6.0E-66
hanks 1.9.5 AGC group; AGC Other; DdK2 3.0E-65
hanks 1.9.5 AGC group; AGC Other; DdK2 2.0E-65
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.1E-65
Pfam IPR000719 EMBL-EBI Protein kinase 4.1E-65
Sequence
Target Sequence 
>C. ELEGANS:189102_AT
ccgcaattgcctcatccataatggtgtagtgaagatggcggattttggaatgtgtcgcgc
tacagccgtctacaaagtcgacctttcgaaacctctgaacgttcgctggctagctccgga
ggtctggaccaacggagagactcgctacaacacagatgtctacgcgtttggtgtcatgat
ttgggagttcttcatcaccccataccaatccccctacaccgaatggaaaggatatactgt
taagcaaaaagttcgaggtggctaccggatgcaaccgccggagggcatgccgaaagacgt
ggcatctctgcttgccgagtgctggaaccacgatcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCGCAATTGCCTCATCCATAATGGT 667 261 918 Antisense
TTTTGGAATGTGTCGCGCTACAGCC 469 677 960 Antisense
ACAGCCGTCTACAAAGTCGACCTTT 265 109 979 Antisense
GTCGACCTTTCGAAACCTCTGAACG 400 417 994 Antisense
CTAGCTCCGGAGGTCTGGACCAACG 560 223 1027 Antisense
GTCTACGCGTTTGGTGTCATGATTT 166 469 1075 Antisense
TTTGGGAGTTCTTCATCACCCCATA 207 667 1097 Antisense
CAATCCCCCTACACCGAATGGAAAG 225 179 1123 Antisense
GTTCGAGGTGGCTACCGGATGCAAC 156 443 1168 Antisense
GAAAGACGTGGCATCTCTGCTTGCC 128 361 1209 Antisense
TTGCCGAGTGCTGGAACCACGATCC 627 701 1229 Antisense
Sequence Source Affymetrix Proprietary Database