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[189081_at] aminoacylase-1

Description C10C5.5 /REP_DB=WormBase Gene ID /WP=CE03013 /TR=Q17900 /GB=CAA92446.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=aminoacylase-1
Cluster 6grp_total > 67      4grp_total > 44      6grp_total_sub > Increase      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 188
1 2 3 4 range
A 139.6
(1.1)
P 		200.5
(3)
P 		51
(-1.8)
A 		13
(-3)
A 		188
B 152.7
(2.6)
P 		162.3
(3)
P 		74
(-0.9)
A 		27.4
(-3)
A 		135
C 163.4
(3)
P 		150.1
(2)
P 		83.8
(-3)
P 		138.7
(1.1)
A 		80
avr 151.9
(2) 		171
(3) 		69.6
(-2.5) 		59.7
(-3) 		111

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 37
1 2 3 4 5 6 range
A 5.1
(-2.7)
A 		6.5
(-2.4)
A 		38.9
(2.9)
A 		3.1
(-3)
A 		8.1
(-2.2)
A 		39.5
(3)
A 		36
B 9.2
(-2.6)
A 		17.6
(-0.5)
A 		21.2
(0.5)
A 		7.4
(-3)
A 		31.4
(3)
A 		11.2
(-2.1)
A 		24
C 28.4
(1.8)
A 		7.5
(-2.1)
A 		2.6
(-3)
A 		9.3
(-1.8)
A 		5.9
(-2.4)
A 		34.9
(3)
A 		32
avr 14.2
(-0.9) 		10.5
(-1.9) 		20.9
(0.9) 		6.6
(-3) 		15.1
(-0.7) 		28.5
(3) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 52
1 2 3 4 range
A 50.8
(3)
P 		43.5
(2.1)
P 		13.3
(-1.6)
A 		1.9
(-3)
A 		49
B 48.7
(3)
P 		40.1
(1.8)
P 		17.1
(-1.4)
A 		5.8
(-3)
A 		43
C 54.1
(3)
P 		43.2
(0.9)
P 		29.2
(-1.9)
P 		23.4
(-3)
A 		31
avr 51.2
(3) 		42.3
(1.7) 		19.9
(-1.6) 		10.4
(-3) 		41

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 0.9
(-2.9)
A 		2.3
(-2)
A 		8.5
(2.3)
A 		0.8
(-3)
A 		2.5
(-1.8)
A 		9.6
(3)
A 		9
B 3.2
(-2.3)
A 		5.9
(-0.8)
A 		5.1
(-1.3)
A 		2
(-3)
A 		12.8
(3)
A 		4.2
(-1.8)
A 		11
C 10.5
(2.3)
A 		2.3
(-2.1)
A 		0.7
(-3)
A 		1.9
(-2.3)
A 		1.9
(-2.3)
A 		11.7
(3)
A 		11
avr 4.9
(-0.1) 		3.5
(-1.3) 		4.8
(-0.2) 		1.6
(-3) 		5.7
(0.6) 		8.5
(3) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189081_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9291
Sequence Type Exemplar sequence
Representative Public ID C10C5.5 NCBI
Target Description C10C5.5 /REP_DB=WormBase Gene ID /WP=CE03013 /TR=Q17900 /GB=CAA92446.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=aminoacylase-1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069251(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069251 NCBI Caenorhabditis elegans C10C5.5 (aminoacylase-1) mRNA, complete cds. 11/11 None
SNAP00000010267 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9381492:9383092:1 11/11 None
GENEFINDER00000010270 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9381492:9383092:1 11/11 None
C10C5.5 ENSEMBL cdna:known chromosome:CEL140:IV:9381492:9383092:1 gene:C10C5.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9381497-9383098(+) 100.0 100.0
Public Domain and Genome References
Gene Title aminoacylase-1
Ensembl C10C5.5
Entrez Gene 177769 Entrez gene
SwissProt Q17900 EMBL-EBI
WormBase CE36099 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:253033_AT aminoacylase, putative / N-acyl-L-amino-acid amidohydrolase, putative at
CANINE:1592296_AT similar to aminoacylase 1 cfa
CANINE_2:CFA.13503.1.S1_AT similar to aminoacylase 1 cfa
CANINE_2:CFA.13503.1.S1_S_AT similar to aminoacylase 1 cfa
CANINE_2:CFA.18715.1.S1_S_AT similar to aminoacylase 1 cfa
CANINE_2:CFAAFFX.15587.1.S1_AT similar to aminoacylase 1 cfa
CANINE_2:CFAAFFX.15598.1.S1_AT similar to aminoacylase 1 cfa
DROSOPHILA_2:1634971_AT dm
DROSGENOME1:151952_AT dm
HG-U133_PLUS_2:202740_AT aminoacylase 1 hs
HG-FOCUS:202740_AT aminoacylase 1 hs
HG-U133A_2:202740_AT aminoacylase 1 hs
HG-U133A:202740_AT aminoacylase 1 hs
HG-U95AV2:37713_AT aminoacylase 1 hs
HUGENEFL:L07548_AT aminoacylase 1 hs
U133_X3P:G4501900_3P_AT aminoacylase 1 hs
HG-U133_PLUS_2:238849_AT Aminoacylase 1 hs
HG-U133B:238849_AT Aminoacylase 1 hs
HG-U95E:73245_AT Aminoacylase 1 hs
HU35KSUBD:RC_AA485931_AT Aminoacylase 1 hs
U133_X3P:HS.236025.0.A1_3P_AT Aminoacylase 1 hs
MOUSE430_2:1419173_AT aminoacylase 1 mm
MOE430A:1419173_AT aminoacylase 1 mm
MOUSE430A_2:1419173_AT aminoacylase 1 mm
MU11KSUBA:AA709553_AT aminoacylase 1 mm
MG-U74AV2:101387_AT aminoacylase 1 mm
MG-U74BV2:164694_R_AT aminoacylase 1 mm
MU19KSUBA:TC15690_S_AT Aminoacylase 1, mRNA (cDNA clone MGC:11593 IMAGE:3964138) mm
MU19KSUBA:TC23040_AT Aminoacylase 1, mRNA (cDNA clone MGC:11593 IMAGE:3964138) mm
MU19KSUBC:TC39375_AT Aminoacylase 1, mRNA (cDNA clone MGC:11593 IMAGE:3964138) mm
MU19KSUBC:TC39375_G_AT Aminoacylase 1, mRNA (cDNA clone MGC:11593 IMAGE:3964138) mm
RG-U34A:RC_AA891914_AT aminoacylase 1 rn
RAE230A:1372170_AT aminoacylase 1 rn
RAT230_2:1372170_AT aminoacylase 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92446 Hypothetical protein C10C5.5 [Caenorhabditis elegans] ref|NP_501652.2| C10C5.5 [Caenorhabditis elegans] 0.0
blast CAA92445 Hypothetical protein C10C5.3 [Caenorhabditis elegans] ref|NP_501650.1| C10C5.3 [Caenorhabditis elegans] 0.0
blast CAA92447 Hypothetical protein C10C5.4 [Caenorhabditis elegans] ref|NP_501651.1| C10C5.4 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002933 EMBL-EBI Peptidase M20 1.7E-94
Sequence
Target Sequence 
>C. ELEGANS:189081_AT
ggttcctagccagtgccagaaaatttcgcaacgaacaaaaagttgtattggagagtaatc
caaatttaacactgggagatgttacgactttgaacgtgaatattgtaaatggtggagttc
agttcaatgtgattcctgaaaagtttgaagcttatgttgatatgagattgacacctcatg
aagattttaataaaatacgtgaaatgttggatcaatgggcaaagaatgccggagaaggtg
tcacctatgaattttcccaatattctgaccaaaaaccaatatctgcacatactcgagata
attcattctgggctgcatttgaggacagtttgaatcaagaaaactgcaaatttgaaaaag
ggataatggttgcatcaacagattcaagatttgaaggagtaaattccattaacttttccc
caatgatcaacacaccgtttcttccacacgatcacaatga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTTCCTAGCCAGTGCCAGAAAATT 100 507 662 Antisense
GAGATTGACACCTCATGAAGATTTT 455 395 825 Antisense
AGAATGCCGGAGAAGGTGTCACCTA 449 75 884 Antisense
GAAGGTGTCACCTATGAATTTTCCC 181 335 895 Antisense
GAATTTTCCCAATATTCTGACCAAA 518 325 910 Antisense
AAACCAATATCTGCACATACTCGAG 369 125 934 Antisense
GAGATAATTCATTCTGGGCTGCATT 159 397 956 Antisense
TCTGGGCTGCATTTGAGGACAGTTT 432 605 968 Antisense
ATTCCATTAACTTTTCCCCAATGAT 470 5 1064 Antisense
TAACTTTTCCCCAATGATCAACACA 30 639 1071 Antisense
CGTTTCTTCCACACGATCACAATGA 611 247 1097 Antisense
Sequence Source Affymetrix Proprietary Database