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[189069_at] aminoacylase-1

Description C10C5.3 /REP_DB=WormBase Gene ID /WP=CE03011 /TR=Q17898 /GB=CAA92445.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=aminoacylase-1
Cluster 6grp_total > 78      4grp_total > 42      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 142
1 2 3 4 range
A 73.1
(-3)
A 		163.1
(3)
P 		131.2
(0.9)
P 		105.2
(-0.9)
A 		90
B 69.2
(-3)
A 		211.5
(3)
P 		124.2
(-0.7)
P 		75.2
(-2.7)
P 		142
C 91.9
(-3)
A 		181.4
(3)
P 		144.8
(0.5)
P 		125
(-0.8)
A 		90
avr 78.1
(-3) 		185.3
(3) 		133.4
(0.1) 		101.8
(-1.7) 		107

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 168
1 2 3 4 5 6 range
A 33.9
(-3)
A 		40.1
(-2.7)
A 		75.9
(-1.3)
A 		45.2
(-2.5)
A 		88.3
(-0.8)
A 		179.6
(3)
P 		146
B 40.7
(-1.6)
A 		48.8
(-1.2)
A 		42.6
(-1.5)
A 		12.7
(-3)
A 		78.8
(0.2)
A 		135.3
(3)
P 		123
C 36.8
(-1.9)
A 		52.1
(-1.2)
A 		11.6
(-3)
A 		19.8
(-2.6)
A 		71
(-0.4)
A 		146.8
(3)
P 		135
avr 37.1
(-2.5) 		47
(-2) 		43.4
(-2.2) 		25.9
(-3) 		79.4
(-0.5) 		153.9
(3) 		128
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 37
1 2 3 4 range
A 26.6
(0.4)
A 		35.4
(3)
P 		34.3
(2.7)
P 		15.4
(-3)
A 		20
B 22.1
(-2)
A 		52.2
(3)
P 		28.8
(-0.9)
P 		16
(-3)
P 		36
C 30.4
(-1.2)
A 		52.2
(3)
P 		50.5
(2.7)
P 		21.1
(-3)
A 		31
avr 26.4
(-1.2) 		46.6
(3) 		37.9
(1.2) 		17.5
(-3) 		29

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 48
1 2 3 4 5 6 range
A 6.2
(-3)
A 		14.3
(-1.7)
A 		16.5
(-1.4)
A 		11.5
(-2.2)
A 		26.7
(0.3)
A 		43.7
(3)
P 		38
B 14.2
(-1.6)
A 		16.2
(-1.4)
A 		10.4
(-2.1)
A 		3.4
(-3)
A 		32
(0.6)
A 		50.5
(3)
P 		47
C 13.6
(-1.6)
A 		15.9
(-1.3)
A 		3
(-3)
A 		4
(-2.9)
A 		23
(-0.4)
A 		49.1
(3)
P 		46
avr 11.3
(-2.3) 		15.5
(-1.7) 		10
(-2.5) 		6.3
(-3) 		27.2
(0) 		47.8
(3) 		42
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189069_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8501
Sequence Type Exemplar sequence
Representative Public ID C10C5.3 NCBI
Target Description C10C5.3 /REP_DB=WormBase Gene ID /WP=CE03011 /TR=Q17898 /GB=CAA92445.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=aminoacylase-1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069249(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069249 NCBI Caenorhabditis elegans C10C5.3 (aminoacylase-1) mRNA, complete cds. 11/11 None
GENEFINDER00000010271 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9374832:9376585:1 11/11 None
C10C5.3 ENSEMBL cdna:known chromosome:CEL140:IV:9374832:9376441:1 gene:C10C5.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000010265 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9374837-9376405(+) 100.0 100.0
Public Domain and Genome References
Gene Title aminoacylase-1
Ensembl C10C5.3
Entrez Gene 177767 Entrez gene
SwissProt Q17898 EMBL-EBI
WormBase CE03011 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261326_S_AT aminoacylase, putative / N-acyl-L-amino-acid amidohydrolase, putative at
DROSOPHILA_2:1630933_AT dm
DROSGENOME1:150425_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92445 Hypothetical protein C10C5.3 [Caenorhabditis elegans] ref|NP_501650.1| C10C5.3 [Caenorhabditis elegans] 0.0
blast CAA92446 Hypothetical protein C10C5.5 [Caenorhabditis elegans] ref|NP_501652.2| C10C5.5 [Caenorhabditis elegans] 0.0
blast CAA92447 Hypothetical protein C10C5.4 [Caenorhabditis elegans] ref|NP_501651.1| C10C5.4 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002933 EMBL-EBI Peptidase M20 6.7E-92
Pfam IPR002933 EMBL-EBI Peptidase M20 4.5E-85
Sequence
Target Sequence 
>C. ELEGANS:189069_AT
aaactcgagcggtacctggctagtgccagaaaattccgtgatgagcaaaaggctctattg
gaaagtaatcctgatttgacaattggagatgttacaactttgaacgtgaatattgtaaat
ggtggagttcaattcaatgtgattcctgaaaaatttgaagcttttgtcgacataagattg
acgccgtccatagattttaatgaaatgcgaaacaagctggatcaatgggtaaaagatgca
ggagaaggtgtcacttatgaattttcaaagcattccgacttgaaactagtgactccacat
acacgagatgatccattttgggttgcatttgaagatagtttgaaacaagaaaaatgcaag
tttacaactgaagtactcattggatctaccgattcccgcatcgttagagaggctggagtt
cgagcaatcaatttttctccattgataaacactcctcttctagcacatgcacataa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACTCGAGCGGTACCTGGCTAGTG 15 127 652 Antisense
GGCTAGTGCCAGAAAATTCCGTGAT 334 537 669 Antisense
ATTGACGCCGTCCATAGATTTTAAT 316 5 828 Antisense
TCCGACTTGAAACTAGTGACTCCAC 561 589 925 Antisense
GTGACTCCACATACACGAGATGATC 15 483 940 Antisense
GAGATGATCCATTTTGGGTTGCATT 206 397 956 Antisense
AAGTACTCATTGGATCTACCGATTC 641 155 1022 Antisense
GATTCCCGCATCGTTAGAGAGGCTG 235 431 1042 Antisense
GAGAGGCTGGAGTTCGAGCAATCAA 587 395 1058 Antisense
TTCTCCATTGATAAACACTCCTCTT 35 695 1086 Antisense
CTCCTCTTCTAGCACATGCACATAA 596 235 1103 Antisense
Sequence Source Affymetrix Proprietary Database