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[189065_at] Tyrosinase

Description C02C2.1 /REP_DB=WormBase Gene ID /WP=CE06754 /TR=SW:P34269 /GB=AAA27909.2 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Tyrosinase
Cluster 6grp_highest_10_10 > 99      6grp_high1_10_10 > 91      4grp_highest_8_8 > 09      4grp_high_8_8 > 53      6grp_highest_nonorm > 55      6grp_total > 94      4grp_total > 58      6grp_cgc > 88      6grp_high1_sub > 05      6grp_total_sub > Hat      6grp_rule_based > S5      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1195
1 2 3 4 range
A 587
(-0.4)
P 		1132.2
(3)
P 		1054.1
(2.5)
P 		179.1
(-3)
P 		953
B 591.8
(-0.8)
P 		1091.4
(1.7)
P 		1340.6
(3)
P 		145.9
(-3)
P 		1195
C 534.4
(-1)
P 		1186.8
(3)
P 		1116.2
(2.6)
P 		202.3
(-3)
P 		985
avr 571.1
(-0.6) 		1136.8
(2.8) 		1170.3
(3) 		175.8
(-3) 		995

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1947
1 2 3 4 5 6 range
A 900.3
(-2.3)
P 		712.5
(-3)
P 		1233.6
(-1.2)
P 		1460
(-0.4)
P 		2444.4
(3)
P 		1192.2
(-1.3)
P 		1732
B 1025.8
(-2.2)
P 		784.8
(-3)
P 		1255.5
(-1.5)
P 		1473.5
(-0.8)
P 		2629
(3)
P 		1307.4
(-1.3)
P 		1844
C 863.2
(-2.4)
P 		681.7
(-3)
P 		1147.1
(-1.6)
P 		1247.9
(-1.2)
P 		2614.9
(3)
P 		1471.2
(-0.5)
P 		1933
avr 929.8
(-2.3) 		726.3
(-3) 		1212.1
(-1.4) 		1393.8
(-0.8) 		2562.8
(3) 		1323.6
(-1) 		1837
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 363
1 2 3 4 range
A 213.7
(1.5)
P 		245.8
(2.3)
P 		275.6
(3)
P 		26.2
(-3)
P 		249
B 188.7
(0.4)
P 		269.6
(2.1)
P 		310.6
(3)
P 		31.1
(-3)
P 		280
C 176.9
(-0.6)
P 		341.2
(2.2)
P 		389
(3)
P 		34.1
(-3)
P 		355
avr 193.1
(0.3) 		285.5
(2.2) 		325.1
(3) 		30.5
(-3) 		295

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 902
1 2 3 4 5 6 range
A 166
(-3)
P 		253.4
(-2.1)
P 		268.7
(-1.9)
P 		370.3
(-0.9)
P 		737.6
(3)
P 		290.3
(-1.7)
P 		572
B 356.9
(-2.3)
P 		261.2
(-3)
P 		304.9
(-2.7)
P 		390.3
(-2)
P 		1068.1
(3)
P 		487.5
(-1.3)
P 		807
C 319.9
(-1.9)
P 		208
(-3)
P 		291.9
(-2.2)
P 		251
(-2.6)
P 		846.2
(3)
P 		492.5
(-0.3)
P 		638
avr 280.9
(-2.6) 		240.9
(-3) 		288.5
(-2.6) 		337.2
(-2.1) 		884
(3) 		423.4
(-1.3) 		643
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189065_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6259
Sequence Type Exemplar sequence
Representative Public ID C02C2.1 NCBI
Target Description C02C2.1 /REP_DB=WormBase Gene ID /WP=CE06754 /TR=SW:P34269 /GB=AAA27909.2 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Tyrosinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066310(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066310 NCBI Caenorhabditis elegans C02C2.1 (Tyrosinase) mRNA, complete cds. 11/11 None
SNAP00000005402 ENSEMBL cdna:SNAP chromosome:CEL140:III:7873709:7876785:1 11/11 None
GENEFINDER00000005408 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:7873709:7876785:1 11/11 None
C02C2.1.2 ENSEMBL cdna:known chromosome:CEL140:III:7873701:7877020:1 gene:C02C2.1 11/11 None
C02C2.1.1 ENSEMBL cdna:known chromosome:CEL140:III:7873703:7877020:1 gene:C02C2.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7873706-7876783(+) 100.0 100.0
Public Domain and Genome References
Gene Title Tyrosinase
Gene Symbol tyr-1
Ensembl C02C2.1
Entrez Gene 176105 Entrez gene
SwissProt P34269 EMBL-EBI
WormBase CE06754 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA27909 Tyrosinase protein 1 [Caenorhabditis elegans] ref|NP_498711.1| C02C2.1 [Caenorhabditis elegans] sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor 0.0
blast CAE66890 Hypothetical protein CBG12271 [Caenorhabditis briggsae] 0.0
blast CAE66891 Hypothetical protein CBG12272 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002227 EMBL-EBI Tyrosinase 7.9E-14
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 5.0E-12
Pfam IPR003582 EMBL-EBI Metridin-like ShK toxin 3.5E-15
Sequence
Target Sequence 
>C. ELEGANS:189065_AT
gcggatctcaatatctgttctgtgatacacgtggcaatccacattgcgtggcaaaggtga
agccaggtggtttgtgccgtggattcgaaggattagattcttgttacatgggtacatgtg
ttgctggatggtgtagaggtggacaacagttccaacagccagcgcaaaccactgcagtgg
ctactgttcaacaacctcagcagcagccccagcaacagcaaccacagcaacagagaccag
ccacaaccccacaatctaattgctacaacgaagatccatgctgtaatcagtggtctcgtc
agaatgagtgtcgaacaaatacagtttacatgaatagatattgtaggaaatcttgtggat
tgtgtcagtctaatgataacaatagaggatgtcatgatcgtcacatatcttgtgcctact
ggcgtggacagaacttctgtacccgccgtcgtcaatggatggctgaaaattgtcaagcaa
catgtggatggtgcaatatgaacgaagctcaattatgtgcatcagttgctcgtcaatcaa
gaagagttcgaagaaatgcaaagttctggctcactgagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGGATCTCAATATCTGTTCTGTGA 504 293 1190 Antisense
CACGTGGCAATCCACATTGCGTGGC 635 197 1217 Antisense
AGGTGGTTTGTGCCGTGGATTCGAA 521 55 1254 Antisense
AGCCAGCGCAAACCACTGCAGTGGC 660 83 1346 Antisense
GCTACTGTTCAACAACCTCAGCAGC 382 299 1369 Antisense
GATCCATGCTGTAATCAGTGGTCTC 17 417 1462 Antisense
GATCGTCACATATCTTGTGCCTACT 139 419 1585 Antisense
GTGCCTACTGGCGTGGACAGAACTT 499 477 1601 Antisense
TACCCGCCGTCGTCAATGGATGGCT 632 647 1629 Antisense
ATGTGCATCAGTTGCTCGTCAATCA 83 49 1704 Antisense
AATGCAAAGTTCTGGCTCACTGAGC 329 165 1744 Antisense
Sequence Source Affymetrix Proprietary Database