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[189027_at] kringle domain

Description T22A3.6 /REP_DB=WormBase Gene ID /WP=CE25122 /TR=P91823 /GB=CAB03383.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=kringle domain
Cluster 6grp_total > 49      4grp_total > 08      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 52
1 2 3 4 range
A 7.3
(-2)
A 		1.6
(-3)
A 		34.2
(2.5)
A 		37.1
(3)
A 		36
B 18.8
(-3)
A 		39.7
(3)
A 		27
(-0.6)
A 		19.2
(-2.9)
A 		21
C 27.9
(-0.7)
A 		12
(-3)
A 		14.6
(-2.6)
A 		53.2
(3)
P 		41
avr 18
(-2.9) 		17.8
(-3) 		25.3
(-0.6) 		36.5
(3) 		19

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 52.6
(3)
A 		3.2
(-3)
A 		24.1
(-0.5)
A 		12.4
(-1.9)
A 		33.2
(0.6)
A 		25.7
(-0.3)
A 		49
B 7.4
(-3)
A 		39.7
(3)
A 		15.6
(-1.5)
A 		27.1
(0.7)
A 		28.1
(0.8)
A 		28.7
(1)
A 		32
C 14.5
(0.6)
A 		9.2
(-1.1)
A 		13.4
(0.3)
A 		5.5
(-2.3)
A 		3.2
(-3)
A 		21.8
(3)
A 		19
avr 24.8
(2.7) 		17.4
(-1.6) 		17.7
(-1.4) 		15
(-3) 		21.5
(0.8) 		25.4
(3) 		10
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 2.6
(-1.4)
A 		0.3
(-3)
A 		8.9
(3)
A 		5.4
(0.6)
A 		9
B 6
(-1)
A 		9.8
(3)
A 		6.3
(-0.7)
A 		4.1
(-3)
A 		6
C 9.2
(3)
A 		3.5
(-3)
A 		5.1
(-1.3)
A 		9
(2.8)
P 		6
avr 5.9
(0.7) 		4.5
(-3) 		6.8
(3) 		6.2
(1.4) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 9.7
(2.8)
A 		1.1
(-3)
A 		5.2
(-0.2)
A 		3.1
(-1.7)
A 		10
(3)
A 		6.3
(0.5)
A 		9
B 2.6
(-3)
A 		13.2
(3)
A 		3.8
(-2.3)
A 		7.2
(-0.4)
A 		11.4
(2)
A 		10.7
(1.6)
A 		11
C 5.4
(1.2)
A 		2.8
(-1.3)
A 		3.4
(-0.7)
A 		1.1
(-2.9)
A 		1
(-3)
A 		7.3
(3)
A 		6
avr 5.9
(-0.1) 		5.7
(-0.3) 		4.1
(-2.6) 		3.8
(-3) 		7.5
(2.2) 		8.1
(3) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 189027_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1992
Sequence Type Exemplar sequence
Representative Public ID T22A3.6 NCBI
Target Description T22A3.6 /REP_DB=WormBase Gene ID /WP=CE25122 /TR=P91823 /GB=CAB03383.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=kringle domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060372(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060372 NCBI Caenorhabditis elegans T22A3.6 (T22A3.6) mRNA, complete cds. 10/11 None
SNAP00000000337 ENSEMBL cdna:SNAP chromosome:CEL140:I:10603114:10606578:1 10/11 None
GENEFINDER00000000340 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10604355:10606578:1 11/11 None
T22A3.6 ENSEMBL cdna:known chromosome:CEL140:I:10603081:10606578:1 gene:T22A3.6 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10603011-10606144(+) 97.52 100.0
Public Domain and Genome References
Gene Title kringle domain
Ensembl T22A3.6
Entrez Gene 188711 Entrez gene
SwissProt P91823 EMBL-EBI
WormBase CE28689 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB03383 Hypothetical protein T22A3.6 [Caenorhabditis elegans] ref|NP_492773.1| T22A3.6 [Caenorhabditis elegans] 0.0
blast CAE56593 Hypothetical protein CBG24340 [Caenorhabditis briggsae] 1.0E-165
blast CAE56593 Hypothetical protein CBG24340 [Caenorhabditis briggsae] 1.0E-160
blast CAE56594 Hypothetical protein CBG24341 [Caenorhabditis briggsae] 2.0E-20
Protein Domains
Database ID Description E-Value
Pfam IPR000001 EMBL-EBI Kringle 1.3E-6
Pfam IPR000001 EMBL-EBI Kringle 1.3E-6
Pfam IPR000001 EMBL-EBI Kringle 1.3E-6
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492773.1 1 85-107
T22A3.6 1 85-107
SNAP00000000337 1 59-81
Sequence
Target Sequence 
>C. ELEGANS:189027_AT
cgagatctatgttttccgagttttaatgaacatgaaatattcacgtatcaacaaggaatc
ttactcgatgcaataattgaagatgaactgacaatatctggatgtacattctggagacga
tgcttctcatcatgtcaagatgacttggcaacttgttggctgaaatctcaaaaaggatat
tttgggtcaaaagctaccagtgtcagtgggaaacagtgtattccatggactcaagccacg
tcggaaatattgagtatggtcaaagtgaattccacgtcatcaggtgtctatcatatgtac
catcggcttctttttgaggatcccagtcaatttttcactgaaagtagacttttcatgaat
actgaagcctcttgtatgcttctgaaccggagaaactcagtggaagttaagaattcatac
aaagaatcaccattttttacgaacgagaaattggtttcggaatttgaaaaattattccaa
caaggtcctggatgctttgtcaaacaggtattggaaatcagtaatttttgtgaaacgtgg
tgtataaaggcgcacagctttattcatatggg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGAGATCTATGTTTTCCGAGTTTTA 174 251 1135 Antisense
GGAGACGATGCTTCTCATCATGTCA 468 519 1247 Antisense
AAGATGACTTGGCAACTTGTTGGCT 509 155 1271 Antisense
TTCCATGGACTCAAGCCACGTCGGA 462 699 1355 Antisense
GTGTCTATCATATGTACCATCGGCT 162 487 1418 Antisense
CCATCGGCTTCTTTTTGAGGATCCC 40 271 1434 Antisense
TGAGGATCCCAGTCAATTTTTCACT 107 555 1449 Antisense
CCTCTTGTATGCTTCTGAACCGGAG 115 269 1502 Antisense
GAATCACCATTTTTTACGAACGAGA 385 327 1558 Antisense
CAAGGTCCTGGATGCTTTGTCAAAC 496 183 1615 Antisense
AGGCGCACAGCTTTATTCATATGGG 433 53 1682 Antisense
Sequence Source Affymetrix Proprietary Database