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[188998_s_at] p-glycoprotein

Description C05A9.1 /REP_DB=WormBase Gene ID /WP=CE05221 /TR=Q17645 /GB=CAA94202.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=p-glycoprotein
Cluster 6grp_high1_10_10 > 07      6grp_total > 07      4grp_total > 55      6grp_cgc > 11      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 269
1 2 3 4 range
A 281.3
(3)
P 		93.1
(-1.9)
P 		63.6
(-2.7)
P 		53.1
(-3)
A 		228
B 296.6
(3)
P 		54.1
(-2.4)
P 		84
(-1.7)
P 		27.8
(-3)
A 		269
C 242.4
(3)
P 		74.1
(-1.9)
P 		76.5
(-1.9)
P 		38.2
(-3)
A 		204
avr 273.4
(3) 		73.8
(-2.1) 		74.7
(-2.1) 		39.7
(-3) 		234

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 192
1 2 3 4 5 6 range
A 148
(3)
P 		64.7
(-1.8)
P 		90.3
(-0.4)
P 		70.5
(-1.5)
P 		70.8
(-1.5)
P 		44.9
(-3)
A 		103
B 146.5
(3)
P 		112.8
(1.1)
P 		43.4
(-2.7)
P 		42.3
(-2.8)
A 		38.4
(-3)
P 		77.9
(-0.8)
P 		108
C 219.8
(3)
P 		102.7
(-0.7)
P 		87.8
(-1.1)
P 		89.5
(-1.1)
P 		27.7
(-3)
A 		48.6
(-2.3)
P 		192
avr 171.4
(3) 		93.4
(-0.7) 		73.8
(-1.7) 		67.4
(-2) 		45.6
(-3) 		57.1
(-2.5) 		126
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 97
1 2 3 4 range
A 102.4
(3)
P 		20.2
(-2.2)
P 		16.6
(-2.4)
P 		7.8
(-3)
A 		95
B 94.6
(3)
P 		13.4
(-2.5)
P 		19.5
(-2.1)
P 		5.9
(-3)
A 		89
C 80.2
(3)
P 		21.3
(-1.8)
P 		26.7
(-1.3)
P 		6.4
(-3)
A 		74
avr 92.4
(3) 		18.3
(-2.2) 		20.9
(-2) 		6.7
(-3) 		86

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 73
1 2 3 4 5 6 range
A 27.3
(3)
P 		23
(1.4)
P 		19.7
(0.2)
P 		17.9
(-0.4)
P 		21.4
(0.8)
P 		10.9
(-3)
A 		16
B 51
(3)
P 		37.5
(1)
P 		10.5
(-3)
P 		11.2
(-2.9)
A 		15.6
(-2.2)
P 		29.1
(-0.2)
P 		41
C 81.5
(3)
P 		31.3
(-1.2)
P 		22.3
(-1.9)
P 		18
(-2.3)
P 		9
(-3)
A 		16.3
(-2.4)
P 		73
avr 53.3
(3) 		30.6
(-0.6) 		17.5
(-2.7) 		15.7
(-2.9) 		15.3
(-3) 		18.8
(-2.4) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188998_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16309
Sequence Type Exemplar sequence
Representative Public ID C05A9.1 NCBI
Target Description C05A9.1 /REP_DB=WormBase Gene ID /WP=CE05221 /TR=Q17645 /GB=CAA94202.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=p-glycoprotein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077409(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077409 NCBI Caenorhabditis elegans C05A9.1 (p-glycoprotein) mRNA, complete cds. 11/11 None
SNAP00000001257 ENSEMBL cdna:SNAP chromosome:CEL140:X:10854304:10856022:-1 11/11 None
C05A9.1 ENSEMBL cdna:known chromosome:CEL140:X:10854249:10859099:-1 gene:C05A9.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10854303-10859099(-) 100.0 100.0
Public Domain and Genome References
Gene Title p-glycoprotein
Gene Symbol pgp-5
Ensembl C05A9.1
Entrez Gene 181276 Entrez gene
SwissProt Q17645 EMBL-EBI
WormBase CE05221 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
166 nucleotide binding inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94202 Hypothetical protein C05A9.1 [Caenorhabditis elegans] ref|NP_509810.1| C05A9.1 [Caenorhabditis elegans] 0.0
blast CAA94219 Hypothetical protein T21E8.2 [Caenorhabditis elegans] ref|NP_509812.2| T21E8.2 [Caenorhabditis elegans] 0.0
blast CAE70807 Hypothetical protein CBG17569 [Caenorhabditis briggsae] 0.0
blast CAA94220 Hypothetical protein T21E8.1 [Caenorhabditis elegans] ref|NP_509813.1| T21E8.1 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 6.5E-24
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 3.2E-29
Pfam IPR003439 EMBL-EBI ABC transporter 4.4E-66
Pfam IPR003439 EMBL-EBI ABC transporter 4.3E-57
Pfam IPR001140 EMBL-EBI ABC transporter, transmembrane region 2.8E-23
Pfam IPR003439 EMBL-EBI ABC transporter 4.3E-57
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509810.1 12 5-27,127-149,203-222,227-244,316-335,342-364,714-736,756-778,835-857,937-959,974-996,1003-1022
C05A9.1 12 5-27,127-149,203-222,227-244,316-335,342-364,714-736,756-778,835-857,937-959,974-996,1003-1022
SNAP00000001257 4 43-65,145-167,182-204,211-230
Sequence
Target Sequence 
>C. ELEGANS:188998_S_AT
gtggtaaatctactataatatctttattggaaagattttatcatgctgtagatggagaag
tcaaaattgatgaggaaaatgtggttgacgtcaatttgcaccatcttcgcgaaagtgtat
ctttagtttcacaagaacccgtattattcaactgctcaattaaagaaaacttcttgtttg
gaatttctcacaatgcatctcaattagaaattgatcaggcattaaaagttgcaaacgctt
ttagttttgtaagccagttcccacag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGGTAAATCTACTATAATATCTTT 128 489 3236 Antisense
GGAAAGATTTTATCATGCTGTAGAT 627 527 3264 Antisense
GTTGACGTCAATTTGCACCATCTTC 175 439 3319 Antisense
AATTTGCACCATCTTCGCGAAAGTG 600 173 3328 Antisense
ACCATCTTCGCGAAAGTGTATCTTT 26 87 3335 Antisense
GTATCTTTAGTTTCACAAGAACCCG 527 453 3352 Antisense
GAACCCGTATTATTCAACTGCTCAA 349 347 3370 Antisense
AACTTCTTGTTTGGAATTTCTCACA 213 139 3403 Antisense
GGAATTTCTCACAATGCATCTCAAT 625 533 3415 Antisense
TTGCAAACGCTTTTAGTTTTGTAAG 502 701 3464 Antisense
TAGTTTTGTAAGCCAGTTCCCACAG 215 651 3477 Antisense
Sequence Source Affymetrix Proprietary Database