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[188984_s_at] CHL1 protein

Description M03C11.2 /REP_DB=WormBase Gene ID /WP=CE03493 /TR=Q21489 /GB=CAA88959.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=CHL1 protein
Cluster 6grp_total > 95      4grp_total > 57      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 62
1 2 3 4 range
A 9.2
(-2.9)
A 		50
(3)
A 		8.6
(-3)
A 		23.5
(-0.8)
A 		41
B 15.2
(-2.3)
A 		28.5
(-1)
A 		69.3
(3)
A 		7.8
(-3)
A 		62
C 45.9
(1.5)
A 		36.3
(0.4)
A 		58.7
(3)
A 		7.5
(-3)
A 		51
avr 23.4
(-1.1) 		38.3
(1.7) 		45.5
(3) 		12.9
(-3) 		33

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 158
1 2 3 4 5 6 range
A 55.9
(-3)
A 		61.8
(-2.6)
A 		66.6
(-2.3)
A 		135.4
(2.4)
A 		122.7
(1.6)
M 		143.8
(3)
P 		88
B 48.2
(-2.6)
A 		40.3
(-3)
A 		48.7
(-2.6)
A 		69.7
(-1.6)
M 		95.6
(-0.3)
P 		162.9
(3)
P 		123
C 24.6
(-2.2)
A 		17.8
(-2.5)
A 		4.9
(-3)
A 		127.5
(2)
A 		107.9
(1.2)
P 		153
(3)
P 		148
avr 42.9
(-2.8) 		40
(-3) 		40.1
(-3) 		110.9
(0.8) 		108.7
(0.6) 		153.2
(3) 		113
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 19
1 2 3 4 range
A 3.4
(-2.2)
A 		10.9
(3)
A 		2.3
(-3)
A 		3.4
(-2.2)
A 		9
B 4.8
(-1.7)
A 		7
(-0.8)
A 		16.1
(3)
A 		1.7
(-3)
A 		14
C 15.2
(1.4)
A 		10.4
(-0.1)
A 		20.4
(3)
A 		1.3
(-3)
A 		19
avr 7.8
(0.2) 		9.4
(1.1) 		12.9
(3) 		2.1
(-3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 60
1 2 3 4 5 6 range
A 10.3
(-3)
A 		22
(-0.4)
A 		14.5
(-2.1)
A 		34.3
(2.4)
A 		37
(3)
M 		35
(2.6)
P 		27
B 16.8
(-2.4)
A 		13.4
(-2.8)
A 		11.8
(-3)
A 		18.5
(-2.2)
M 		38.9
(0.3)
P 		60.8
(3)
P 		49
C 9.1
(-2.1)
A 		5.4
(-2.5)
A 		1.3
(-3)
A 		25.6
(-0.1)
A 		34.9
(1)
P 		51.2
(3)
P 		50
avr 12.1
(-2.6) 		13.6
(-2.3) 		9.2
(-3) 		26.1
(-0.5) 		36.9
(1.2) 		49
(3) 		40
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188984_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6663
Sequence Type Exemplar sequence
Representative Public ID M03C11.2 NCBI
Target Description M03C11.2 /REP_DB=WormBase Gene ID /WP=CE03493 /TR=Q21489 /GB=CAA88959.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=CHL1 protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066894(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066894 NCBI Caenorhabditis elegans M03C11.2 (M03C11.2) mRNA, complete cds. 11/11 A 
SNAP00000000515 ENSEMBL cdna:SNAP chromosome:CEL140:III:10399179:10405121:-1 11/11 None
GENEFINDER00000000554 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10399179:10405121:-1 11/11 None
M03C11.2 ENSEMBL cdna:known chromosome:CEL140:III:10398705:10405122:-1 gene:M03C11.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10399174-10405117(-) 100.0 100.0
Public Domain and Genome References
Gene Title CHL1 protein
Ensembl M03C11.2
Entrez Gene 176457 Entrez gene
SwissProt Q21489 EMBL-EBI
WormBase CE03493 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260159_AT helicase-related at
CANINE_2:CFAAFFX.24097.1.S1_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 cfa
CANINE_2:CFAAFFX.24097.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 cfa
CANINE_2:CFAAFFX.24099.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 cfa
DROSOPHILA_2:1626359_AT dm
DROSGENOME1:154240_AT dm
CHICKEN:GGA.11265.1.A1_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; yeast CHL1 homolog; DEAD/H box-11 (CHL1-related helicase gene-1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase) gga
CHICKEN:GGAAFFX.24068.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; yeast CHL1 homolog; DEAD/H box-11 (CHL1-related helicase gene-1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase) gga
CHICKEN:GGAAFFX.8207.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; yeast CHL1 homolog; DEAD/H box-11 (CHL1-related helicase gene-1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase) gga
HG-U133_PLUS_2:208159_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:208159_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:208159_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-FOCUS:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:232816_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133B:232816_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:210206_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:210206_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:210206_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBA:U75968_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBA:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBB:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBC:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBD:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HUGENEFL:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HC-G110:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HUGENEFL:U75968_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:G1517815_3P_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:G13787196_3P_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:HS.129998.3.S1_3P_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-FOCUS:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95AV2:31935_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95C:57224_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:89108_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:G13787196_3P_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95C:57224_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:73694_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:73062_R_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:86738_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
MG-U74BV2:111583_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOE430B:1438447_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOUSE430_2:1438447_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOE430B:1441062_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOUSE430_2:1441062_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
RAE230B:1395376_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
RAT230_2:1395376_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
RAE230B:1391118_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
RAT230_2:1391118_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
YEAST_2:1777889_AT Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism inferred from electronic annotation QuickGO AmiGO
6289 nucleotide-excision repair inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
4003 ATP-dependent DNA helicase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
8026 ATP-dependent helicase activity inferred from electronic annotation QuickGO AmiGO
16818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88959 Hypothetical protein M03C11.2 [Caenorhabditis elegans] ref|NP_499295.1| M03C11.2 [Caenorhabditis elegans] 0.0
blast CAE71476 Hypothetical protein CBG18394 [Caenorhabditis briggsae] 0.0
blast NP_001007320 hypothetical protein LOC492353 [Danio rerio] gb|AAH85645.1| Zgc:92172 [Danio rerio] 1.0E-127
blast NP_001007320 hypothetical protein LOC492353 [Danio rerio] gb|AAH85645.1| Zgc:92172 [Danio rerio] 1.0E-125
Protein Domains
Database ID Description E-Value
Pfam IPR010614 EMBL-EBI DEAD_2 1.1E-76
Pfam IPR010614 EMBL-EBI DEAD_2 4.6E-82
Pfam IPR010614 EMBL-EBI DEAD_2 4.6E-82
Sequence
Target Sequence 
>C. ELEGANS:188984_S_AT
taccacgttgagatcgttggccacgtcaattcaggccctgattccgcatattccgaatgg
agttgtgatctttgtgccgtcatacgactttttgttcaatttccagaaaaagatgaagga
atttgggattttgaagcggatcgaggaaaagaaggccgtattcacagaaagccggcaacc
aacatcagacgtctgggaccgattcagccgagctgcaaaaacatcgaaaggagccattct
atttgctgtcgtcggcggtaaaatgagcgagggaataaatttttgtgatgagctcggacg
ggcggtcattgttatcggattaccgtatccgaataagaccagcgtcgagttgagggaacg
gatgaagttcctcgacactcaaatgccgaacggtggaaacctgctctacgaatctctatg
catgcacgccgtgaatcaagccatcggt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACCACGTTGAGATCGTTGGCCACG 78 649 1932 Antisense
TGGCCACGTCAATTCAGGCCCTGAT 601 543 1949 Antisense
CCCTGATTCCGCATATTCCGAATGG 350 259 1967 Antisense
ATGGAGTTGTGATCTTTGTGCCGTC 121 53 1988 Antisense
GTGCCGTCATACGACTTTTTGTTCA 165 477 2005 Antisense
AGAAAGCCGGCAACCAACATCAGAC 371 73 2097 Antisense
ATCAGACGTCTGGGACCGATTCAGC 379 25 2115 Antisense
AGGAGCCATTCTATTTGCTGTCGTC 10 57 2160 Antisense
GGACGGGCGGTCATTGTTATCGGAT 39 525 2227 Antisense
CTACGAATCTCTATGCATGCACGCC 16 227 2337 Antisense
GCACGCCGTGAATCAAGCCATCGGT 117 311 2355 Antisense
Sequence Source Affymetrix Proprietary Database