[Home] | [Total List]

[188961_at] glutaminase

Description DH11.1 /REP_DB=WormBase Gene ID /WP=CE02170 /TR=SW:Q19013 /GB=CAA88938.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=glutaminase
Cluster 6grp_highest_10_10 > 45      6grp_high1_10_10 > 43      4grp_highest_8_8 > 45      4grp_high_8_8 > 09      6grp_highest_nonorm > 73      6grp_total > 10      4grp_total > 23      6grp_high1_sub > 02      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 465
1 2 3 4 range
A 768.8
(3)
P 		303.6
(-3)
P 		341.5
(-2.5)
P 		586.5
(0.6)
P 		465
B 698.3
(2)
P 		389.2
(-2.5)
P 		354.5
(-3)
P 		763.9
(3)
P 		409
C 717.8
(3)
P 		340.9
(-3)
P 		370.6
(-2.5)
P 		646.6
(1.9)
P 		377
avr 728.3
(3) 		344.6
(-3) 		355.5
(-2.8) 		665.7
(2) 		384

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 370
1 2 3 4 5 6 range
A 425.7
(-3)
P 		611.5
(0.4)
P 		755.6
(3)
P 		466.5
(-2.3)
P 		464.2
(-2.3)
P 		494.2
(-1.8)
P 		330
B 389.1
(-3)
P 		605.1
(1.7)
P 		496.9
(-0.7)
P 		519.1
(-0.2)
P 		666
(3)
P 		617.7
(2)
P 		277
C 454.8
(-1.5)
P 		663.7
(3)
P 		602.5
(1.7)
P 		385.9
(-3)
P 		483.5
(-0.9)
P 		563.1
(0.8)
P 		278
avr 423.2
(-3) 		626.8
(3) 		618.3
(2.7) 		457.2
(-2) 		537.9
(0.4) 		558.3
(1) 		204
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 214
1 2 3 4 range
A 279.9
(3)
P 		65.9
(-3)
P 		89.3
(-2.3)
P 		85.8
(-2.4)
P 		214
B 222.7
(3)
P 		96.1
(-2.4)
P 		82.2
(-3)
P 		162.8
(0.4)
P 		141
C 237.6
(3)
P 		98
(-3)
P 		129.2
(-1.7)
P 		109
(-2.5)
P 		140
avr 246.7
(3) 		86.7
(-3) 		100.2
(-2.5) 		119.2
(-1.8) 		160

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 193
1 2 3 4 5 6 range
A 78.5
(-3)
P 		217.5
(3)
P 		164.6
(0.7)
P 		118.3
(-1.3)
P 		140.1
(-0.3)
P 		120.3
(-1.2)
P 		139
B 135.4
(-2.4)
P 		201.4
(0.2)
P 		120.7
(-3)
P 		137.5
(-2.3)
P 		270.6
(3)
P 		230.3
(1.4)
P 		150
C 168.6
(1.4)
P 		202.5
(3)
P 		153.3
(0.6)
P 		77.6
(-3)
P 		156.5
(0.8)
P 		188.5
(2.3)
P 		125
avr 127.5
(-2) 		207.1
(3) 		146.2
(-0.8) 		111.1
(-3) 		189.1
(1.9) 		179.7
(1.3) 		96
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188961_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3629
Sequence Type Exemplar sequence
Representative Public ID DH11.1 NCBI
Target Description DH11.1 /REP_DB=WormBase Gene ID /WP=CE02170 /TR=SW:Q19013 /GB=CAA88938.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=glutaminase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063274(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063274 NCBI Caenorhabditis elegans DH11.1 (glutaminase) mRNA, complete cds. 11/11 None
SNAP00000004561 ENSEMBL cdna:SNAP chromosome:CEL140:II:8008909:8011322:1 11/11 None
GENEFINDER00000004568 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8008605:8011322:1 11/11 None
DH11.1.2 ENSEMBL cdna:known chromosome:CEL140:II:8008541:8011552:1 gene:DH11.1 11/11 None
DH11.1.1 ENSEMBL cdna:known chromosome:CEL140:II:8008596:8011552:1 gene:DH11.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8008905-8011319(+) 100.0 100.0
Public Domain and Genome References
Gene Title glutaminase
Ensembl DH11.1
Entrez Gene 174282 Entrez gene
SwissProt Q19013 EMBL-EBI
WormBase CE28902 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.14966.1.S1_AT similar to Glutaminase, kidney isoform, mitochondrial precursor (GLS) (L-glutamine amidohydrolase) (K-glutaminase) cfa
CANINE_2:CFAAFFX.14969.1.S1_S_AT similar to Glutaminase, kidney isoform, mitochondrial precursor (GLS) (L-glutamine amidohydrolase) (K-glutaminase) cfa
DROSOPHILA_2:1634658_A_AT no extended memory dm
DROSGENOME1:152880_AT no extended memory dm
CHICKEN:GGA.17639.1.S1_S_AT glutaminase gga
CHICKEN:GGA.2058.1.S1_S_AT glutaminase gga
CHICKEN:GGA.2058.1.S1_AT Similar to Glutaminase, kidney isoform, mitochondrial precursor (GLS) (L-glutamine amidohydrolase) (K-glutaminase) gga
HG-U95AV2:34719_AT glutaminase hs
HG-U133A:203159_AT glutaminase hs
HG-U133_PLUS_2:203159_AT glutaminase hs
HG-U133A_2:203159_AT glutaminase hs
HG-U133A:221510_S_AT glutaminase hs
HG-U133_PLUS_2:221510_S_AT glutaminase hs
HG-U133A_2:221510_S_AT glutaminase hs
HG-U133_PLUS_2:211414_AT glutaminase hs
HG-U133A:211414_AT glutaminase hs
HG-U133A_2:211414_AT glutaminase hs
HU35KSUBA:AA243523_AT glutaminase hs
HU35KSUBA:RC_AA182001_I_AT glutaminase hs
HU35KSUBA:RC_AA182001_R_AT glutaminase hs
HU35KSUBB:RC_F02807_AT glutaminase hs
HU35KSUBC:RC_AA521126_AT glutaminase hs
HG-U133A:203157_S_AT glutaminase hs
HG-U133_PLUS_2:203157_S_AT glutaminase hs
HG-U133A_2:203157_S_AT glutaminase hs
HG-U133A:203158_S_AT glutaminase hs
HG-U133_PLUS_2:203158_S_AT glutaminase hs
HG-U133A_2:203158_S_AT glutaminase hs
U133_X3P:G7662327_3P_AT glutaminase hs
U133_X3P:G6002675_3P_X_AT glutaminase hs
U133_X3P:G6002675_3P_AT glutaminase hs
U133_X3P:G6002672_3P_A_AT glutaminase hs
U133_X3P:G5690371_3P_X_AT glutaminase hs
U133_X3P:G5690371_3P_A_AT glutaminase hs
U133_X3P:G4240164_3P_A_AT glutaminase hs
U133_X3P:HS.239189.1.S1_3P_A_AT glutaminase hs
U133_X3P:221510_3P_S_AT glutaminase hs
HG-U133_PLUS_2:223079_S_AT glutaminase hs
HG-U133B:223079_S_AT glutaminase hs
HG-U133_PLUS_2:241034_AT glutaminase hs
HG-U133B:241034_AT glutaminase hs
HG-U95B:43839_F_AT glutaminase hs
HG-U95B:54799_AT glutaminase hs
HG-U95C:57270_F_AT glutaminase hs
HG-U95C:65484_F_AT glutaminase hs
HU35KSUBB:RC_AA088431_AT Glutaminase hs
U133_X3P:HS.68837.0.A1_3P_AT Glutaminase hs
U133_X3P:HS.239189.1.S4_3P_X_AT Glutaminase hs
HG-U133_PLUS_2:223080_AT Glutaminase hs
HG-U133B:223080_AT Glutaminase hs
HG-U95B:47827_AT Glutaminase hs
HG-U133_PLUS_2:239614_X_AT Glutaminase hs
HG-U133B:239614_X_AT Glutaminase hs
HG-U133_PLUS_2:244247_AT Glutaminase hs
HG-U133B:244247_AT Glutaminase hs
HG-U95AV2:31357_AT Glutaminase hs
HG-U95D:72807_AT Glutaminase hs
HG-U95D:75809_AT Glutaminase hs
HU35KSUBB:RC_AA074891_AT Glutaminase hs
HU35KSUBC:RC_AA280288_AT Glutaminase hs
U133_X3P:239614_3P_X_AT Glutaminase hs
U133_X3P:HS.116448.0.A1_3P_AT Glutaminase hs
U133_X3P:HS.88746.0.A1_3P_AT Glutaminase hs
U133_X3P:HS.88746.0.A1_3P_X_AT Glutaminase hs
MG-U74BV2:107334_R_AT glutaminase mm
MG-U74BV2:111865_AT glutaminase mm
MOE430B:1436299_AT glutaminase mm
MOUSE430_2:1436299_AT glutaminase mm
MG-U74BV2:115704_AT MKIAA0838 protein mm
MOE430B:1434657_AT MKIAA0838 protein mm
MOUSE430_2:1434657_AT MKIAA0838 protein mm
MOE430B:1435708_AT MKIAA0838 protein mm
MOUSE430_2:1435708_AT MKIAA0838 protein mm
MG-U74BV2:115843_AT MKIAA0838 protein mm
MG-U74CV2:131851_AT MKIAA0838 protein mm
MOE430B:1438827_AT MKIAA0838 protein mm
MOUSE430_2:1438827_AT MKIAA0838 protein mm
MOE430B:1457211_AT MKIAA0838 protein mm
MOUSE430_2:1457211_AT MKIAA0838 protein mm
MU19KSUBA:TC20869_AT MKIAA0838 protein mm
MU19KSUBB:TC28305_AT MKIAA0838 protein mm
RG-U34A:RC_AI176504_AT glutaminase rn
RG-U34B:RC_AA925755_AT glutaminase rn
RG-U34C:RC_AI177367_AT glutaminase rn
RAE230A:1386932_AT glutaminase rn
RAT230_2:1386932_AT glutaminase rn
RAE230A:1367806_AT glutaminase rn
RAT230_2:1367806_AT glutaminase rn
RAE230A:1367805_AT glutaminase rn
RAT230_2:1367805_AT glutaminase rn
RAE230B:1382521_AT glutaminase rn
RAT230_2:1382521_AT glutaminase rn
RAE230B:1382616_AT glutaminase rn
RAT230_2:1382616_AT glutaminase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6541 glutamine metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4359 glutaminase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88938 Hypothetical protein DH11.1 [Caenorhabditis elegans] ref|NP_495675.1| DH11.1 [Caenorhabditis elegans] sp|Q19013|GLS1_CAEEL Putative glutaminase DH11.1 (GLS) (L-glutamine amidohydrolase) 0.0
blast T20384 hypothetical protein DH11.1 - Caenorhabditis elegans 0.0
blast CAE67780 Hypothetical protein CBG13355 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002110 EMBL-EBI Ankyrin 18.0
Pfam IPR002110 EMBL-EBI Ankyrin 1.7E-5
Pfam IPR007043 EMBL-EBI Glutaminase 1.0E-126
Pfam IPR002110 EMBL-EBI Ankyrin 18.0
Pfam IPR002110 EMBL-EBI Ankyrin 1.7E-5
Pfam IPR007043 EMBL-EBI Glutaminase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:188961_AT
atgtcgggttgccagctaaatcaggagtatctggtgcaatgatagtggtggtgcctaatg
taatgggtatttgtctattttccccaccactggattcacttggtaacagttgtagaggtg
ttgcattctgcaagaaactggtttccactttcaactttcacaattatgactgtcttgttc
ataactccaatattaaaagtgatccaagaagaagagacattcgagagcgtgatcgattaa
tccctgttttccacgtggcaagagctggggatctcccaacaatgagaagattgtatatgc
aaggagaagatttgaatacctctgatcacgatgatagaacagtcttgcatattgcagcta
ctgaaggatatgagacaatgatcaaattcctggttaatgtggcaaaggttgatgtggata
agaaagatcgttggggacggactccgttggatgaagcta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGTCGGGTTGCCAGCTAAATCAGG 541 47 1118 Antisense
TCCCCACCACTGGATTCACTTGGTA 577 595 1198 Antisense
GTTGTAGAGGTGTTGCATTCTGCAA 188 437 1226 Antisense
TGGTTTCCACTTTCAACTTTCACAA 455 551 1256 Antisense
GACTGTCTTGTTCATAACTCCAATA 37 377 1285 Antisense
GTGATCGATTAATCCCTGTTTTCCA 314 483 1346 Antisense
ACGTGGCAAGAGCTGGGGATCTCCC 155 95 1370 Antisense
GATTTGAATACCTCTGATCACGATG 630 427 1426 Antisense
ACAGTCTTGCATATTGCAGCTACTG 360 107 1456 Antisense
GAAAGATCGTTGGGGACGGACTCCG 249 359 1539 Antisense
GGACGGACTCCGTTGGATGAAGCTA 707 517 1552 Antisense
Sequence Source Affymetrix Proprietary Database