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[188959_at] Plasminogen

Description ZK546.15 /REP_DB=WormBase Gene ID /WP=CE02915 /TR=Q23528 /GB=AAA68746.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Plasminogen
Cluster 6grp_total > 99      4grp_total > 40      6grp_cgc > 79      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 51
1 2 3 4 range
A 11.6
(-2.5)
A 		14.4
(-2.2)
A 		57.4
(3)
A 		7.5
(-3)
A 		50
B 6.7
(-3)
A 		22.1
(-0.1)
A 		10.9
(-2.2)
A 		38.5
(3)
A 		32
C 13.9
(-1.2)
A 		7.9
(-3)
A 		27.8
(3)
A 		8.7
(-2.8)
A 		20
avr 10.7
(-3) 		14.8
(-1.8) 		32
(3) 		18.2
(-0.9) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 249
1 2 3 4 5 6 range
A 12.9
(-3)
A 		15.6
(-2.9)
A 		34.1
(-2.5)
A 		12.7
(-3)
A 		189
(1.4)
A 		252.3
(3)
P 		240
B 3.1
(-3)
A 		15.8
(-2.6)
A 		18
(-2.5)
A 		10.8
(-2.8)
A 		193
(3)
P 		165.1
(2.1)
P 		190
C 5.2
(-3)
A 		3.5
(-3)
A 		6.9
(-2.9)
A 		12.1
(-2.8)
A 		138.8
(0.7)
P 		221.7
(3)
P 		218
avr 7.1
(-3) 		11.6
(-2.9) 		19.7
(-2.6) 		11.9
(-2.9) 		173.6
(1.9) 		213
(3) 		206
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 4.2
(-1.7)
A 		3.1
(-2.1)
A 		15
(3)
A 		1.1
(-3)
A 		14
B 2.1
(-3)
A 		5.5
(0.3)
A 		2.5
(-2.6)
A 		8.2
(3)
A 		6
C 4.6
(-0.7)
A 		2.3
(-2.4)
A 		9.7
(3)
A 		1.5
(-3)
A 		8
avr 3.6
(-3) 		3.6
(-3) 		9.1
(3) 		3.6
(-3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 2.4
(-3)
A 		5.6
(-2.7)
A 		7.4
(-2.5)
A 		3.2
(-2.9)
A 		57
(2.6)
A 		61.4
(3)
P 		59
B 1.1
(-3)
A 		5.2
(-2.7)
A 		4.4
(-2.7)
A 		2.9
(-2.9)
A 		78.4
(3)
P 		61.5
(1.7)
P 		77
C 1.9
(-2.9)
A 		1.1
(-3)
A 		1.7
(-3)
A 		2.4
(-2.9)
A 		44.9
(0.6)
P 		74.2
(3)
P 		73
avr 1.8
(-3) 		4
(-2.8) 		4.5
(-2.7) 		2.8
(-2.9) 		60.1
(2.5) 		65.7
(3) 		64
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 188959_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5964
Sequence Type Exemplar sequence
Representative Public ID ZK546.15 NCBI
Target Description ZK546.15 /REP_DB=WormBase Gene ID /WP=CE02915 /TR=Q23528 /GB=AAA68746.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=Plasminogen
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062509(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062509 NCBI Caenorhabditis elegans ZK546.15 (Plasminogen) mRNA, complete cds. 11/11 None
SNAP00000034952 ENSEMBL cdna:SNAP chromosome:CEL140:II:4948246:4949447:-1 11/11 None
GENEFINDER00000034962 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:4948246:4949447:-1 11/11 None
ZK546.15 ENSEMBL cdna:known chromosome:CEL140:II:4948246:4949447:-1 gene:ZK546.15 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:4948243-4949445(-) 100.0 100.0
Public Domain and Genome References
Gene Title Plasminogen
Gene Symbol try-1
Ensembl ZK546.15
Entrez Gene 173856 Entrez gene
SwissProt Q23528 EMBL-EBI
WormBase CE36075 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.29531.1.S1_S_AT similar to protease, serine, 33 cfa
DROSOPHILA_2:1632966_AT dm
DROSGENOME1:155018_AT dm
U133_X3P:HS2.280658.1.S1_3P_S_AT protease, serine, 33 hs
U133_X3P:HS2.280658.1.S1_3P_AT protease, serine, 33 hs
HG-U133_PLUS_2:1552348_AT protease, serine, 33 hs
HG-U133_PLUS_2:1552349_A_AT protease, serine, 33 hs
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4263 chymotrypsin activity inferred from electronic annotation QuickGO AmiGO
4295 trypsin activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA68746 Trypsin-like protease protein 1 [Caenorhabditis elegans] ref|NP_494910.2| ZK546.15 [Caenorhabditis elegans] 1.0E-163
blast AAA68746 Trypsin-like protease protein 1 [Caenorhabditis elegans] ref|NP_494910.2| ZK546.15 [Caenorhabditis elegans] 1.0E-156
blast CAE59027 Hypothetical protein CBG02304 [Caenorhabditis briggsae] 1.0E-142
blast CAE59027 Hypothetical protein CBG02304 [Caenorhabditis briggsae] 1.0E-134
blast CAE59010 Hypothetical protein CBG02286 [Caenorhabditis briggsae] 8.0E-65
Protein Domains
Database ID Description E-Value
Pfam IPR001254 EMBL-EBI Peptidase S1, chymotrypsin 2.4E-72
Pfam IPR001254 EMBL-EBI Peptidase S1, chymotrypsin 3.0E-44
Pfam IPR001254 EMBL-EBI Peptidase S1, chymotrypsin 1.0E-19
Sequence
Target Sequence 
>C. ELEGANS:188959_AT
gagtgggaggacatcgttcaggttctggaagtccacaccgtgtgacagctgtatcgattc
atccatggtataacattggatttccaagttcctatgacttcgcgattatgagaattcatc
cgccagtcaatacttcaactacagctcgcccgatatgtttgccaagccttccagccgtcg
aaaatcggctttgtgtggttaccggctggggatcaacaatcgaaggaagctcattatcgg
caccgactttgcgtgaaatccatgttccacttctatcaacgttgttctgtagcagtcttc
ccaactacattggccgaattcatctcccgtctatgctatgcgctggttatagttatggaa
aaatagactcatgccaggtaacagctgaaatttctgcatttgtgaagcttaccgagtata
tatttgattcgagaagcgtcgagttgggagatagtggcggccctcttatgtgcgctcgcg
acggtcattgggagctgacaggtgttgtgagttggggaattggttgtgctcgtcccggaa
tgcctggagtttatggaaatgtgcattcggcatccacgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGTGGGAGGACATCGTTCAGGTTC 476 399 395 Antisense
GTCCACACCGTGTGACAGCTGTATC 361 477 425 Antisense
TTCATCCGCCAGTCAATACTTCAAC 461 687 509 Antisense
CAACTACAGCTCGCCCGATATGTTT 196 189 530 Antisense
TGTGGTTACCGGCTGGGGATCAACA 548 547 588 Antisense
TTATCGGCACCGACTTTGCGTGAAA 663 679 628 Antisense
GAAATCCATGTTCCACTTCTATCAA 611 361 649 Antisense
TGTTCTGTAGCAGTCTTCCCAACTA 259 563 677 Antisense
AACTACATTGGCCGAATTCATCTCC 155 141 697 Antisense
TGCGCTCGCGACGGTCATTGGGAGC 457 581 865 Antisense
GGAAATGTGCATTCGGCATCCACGT 519 527 949 Antisense
Sequence Source Affymetrix Proprietary Database