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[188950_s_at] flavoprotein

Description C34B2.7 /REP_DB=WormBase Gene ID /WP=CE16895 /TR=O44954 /GB=AAB97539.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=flavoprotein
Cluster 6grp_highest_10_10 > 69      6grp_high1_10_10 > 95      4grp_highest_8_8 > 11      4grp_high_8_8 > 47      6grp_highest_nonorm > 98      6grp_total > 85      4grp_total > 48      6grp_highest_sub > In      6grp_high1_sub > In      6grp_rule_based > S6      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 335
1 2 3 4 range
A 237.6
(-3)
P 		489.3
(2.8)
P 		498.1
(3)
P 		378.1
(0.2)
P 		261
B 304.2
(-3)
P 		402.7
(-0.8)
P 		572.4
(3)
P 		353.3
(-1.9)
P 		268
C 275.9
(-3)
P 		455.8
(1.1)
P 		536.7
(3)
P 		293.1
(-2.6)
P 		261
avr 272.6
(-3) 		449.3
(1) 		535.7
(3) 		341.5
(-1.4) 		263

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1329
1 2 3 4 5 6 range
A 545.7
(-3)
P 		594.5
(-2.6)
P 		826.3
(-0.7)
P 		782.9
(-1.1)
P 		1273.2
(2.9)
P 		1289.3
(3)
P 		744
B 588.4
(-3)
P 		724.1
(-2.3)
P 		1039.5
(-0.6)
P 		1421.4
(1.4)
P 		1684.6
(2.8)
P 		1727
(3)
P 		1139
C 562.9
(-3)
P 		627.5
(-2.7)
P 		763.1
(-2.1)
P 		1364.3
(0.7)
P 		1208.6
(-0)
P 		1874.2
(3)
P 		1311
avr 565.7
(-3) 		648.7
(-2.5) 		876.3
(-1.2) 		1189.5
(0.5) 		1388.8
(1.6) 		1630.2
(3) 		1065
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 138
1 2 3 4 range
A 86.5
(-0.5)
P 		106.2
(1.1)
P 		130.2
(3)
P 		55.3
(-3)
P 		75
B 97
(-0.7)
P 		99.5
(-0.5)
P 		132.6
(3)
P 		75.3
(-3)
P 		57
C 91.3
(-1.2)
P 		131
(0.6)
P 		187.1
(3)
P 		49.4
(-3)
P 		138
avr 91.6
(-0.9) 		112.2
(0.5) 		150
(3) 		60
(-3) 		90

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 584
1 2 3 4 5 6 range
A 100.6
(-3)
P 		211.4
(-0.7)
P 		179.9
(-1.3)
P 		198.6
(-0.9)
P 		384.2
(3)
P 		313.9
(1.5)
P 		284
B 204.7
(-3)
P 		241
(-2.5)
P 		252.4
(-2.4)
P 		376.5
(-0.9)
P 		684.4
(3)
P 		644
(2.5)
P 		480
C 208.7
(-2.8)
P 		191.5
(-3)
P 		194.2
(-3)
P 		274.4
(-1.9)
P 		391.1
(-0.3)
P 		627.4
(3)
P 		436
avr 171.3
(-3) 		214.6
(-2.3) 		208.8
(-2.4) 		283.2
(-1.1) 		486.6
(2.3) 		528.4
(3) 		357
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 188950_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.349
Sequence Type Exemplar sequence
Representative Public ID C34B2.7 NCBI
Target Description C34B2.7 /REP_DB=WormBase Gene ID /WP=CE16895 /TR=O44954 /GB=AAB97539.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=flavoprotein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060397(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060397 NCBI Caenorhabditis elegans C34B2.7 (flavoprotein) mRNA, complete cds. 11/11 None
SNAP00000007247 ENSEMBL cdna:SNAP chromosome:CEL140:I:10691499:10693704:-1 11/11 None
GENEFINDER00000007258 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10691499:10695174:-1 11/11 None
C34B2.7.1 ENSEMBL cdna:known chromosome:CEL140:I:10691407:10693745:-1 gene:C34B2.7 11/11 None
C34B2.7.3 ENSEMBL cdna:known chromosome:CEL140:I:10691407:10694003:-1 gene:C34B2.7 11/11 None
C34B2.7.2 ENSEMBL cdna:known chromosome:CEL140:I:10691407:10693708:-1 gene:C34B2.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10691429-10693635(-) 100.0 100.0
Public Domain and Genome References
Gene Title flavoprotein
Ensembl C34B2.7
Entrez Gene 172968 Entrez gene
SwissProt O44954 EMBL-EBI
WormBase CE16895 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13431_AT succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial, putative / flavoprotein subunit of complex II, putative at
ATH1-121501:265329_AT succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial, putative / flavoprotein subunit of complex II, putative at
YEAST_2:1772202_AT Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
15036 disulfide oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB97539 Hypothetical protein C34B2.7 [Caenorhabditis elegans] ref|NP_492798.1| C34B2.7 [Caenorhabditis elegans] 0.0
blast CAE67342 Hypothetical protein CBG12805 [Caenorhabditis briggsae] 0.0
blast AAB37034 Hypothetical protein C03G5.1 [Caenorhabditis elegans] ref|NP_509446.1| C03G5.1 [Caenorhabditis elegans] sp|Q09508|DHSA_CAEEL Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor (FP) (Flavoprotein subunit of complex II) 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004112 EMBL-EBI Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal 8.7E-95
Pfam IPR003953 EMBL-EBI Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal 1.0E-126
Pfam IPR004112 EMBL-EBI Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal 8.7E-95
Pfam IPR009346 EMBL-EBI GRIM-19 2.0E-104
Pfam IPR003953 EMBL-EBI Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000007258 1 29-51
Sequence
Target Sequence 
>C. ELEGANS:188950_S_AT
atctttggaagatcttgcgctctcactatccttaatgagaacaaaccaggagattcaatc
ccggagcttccggtaaattgtgaagagaaatcgtgtgacaatttgaacggacttttgcac
tcaaaaggagatatttcatctatcgaattaagacaaaagatgcaaatgacaatgcagaaa
catgctgctgttttcagacggggcgatcttttgaaggaaggagtcgataaaatgtcctcc
atctacaaagagcaacaaaatttgaaggcgtgtgccgactctggaaaagtatggaattcg
gagcttgtcgaaactctcgagcttcagaatttgcttatcaacgccaatcaaaccatcgtc
gccgccgaaaatcgcactgaatctcgtggagcccacgctcgtgatgatttccaagaaaga
attgacgaatatgactacagcaatccacttgagggacagcagaaaaaaccgtttgatcag
cactggcgcaagcattccatcatcggtatcgatacgaaaactggagctgttgatttgaca
taccgccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCTTTGGAAGATCTTGCGCTCTCA 85 33 1321 Antisense
GAGATTCAATCCCGGAGCTTCCGGT 443 395 1370 Antisense
GCTGCTGTTTTCAGACGGGGCGATC 184 297 1504 Antisense
TTGAAGGCGTGTGCCGACTCTGGAA 17 703 1582 Antisense
GAGCTTGTCGAAACTCTCGAGCTTC 182 389 1621 Antisense
GCTTATCAACGCCAATCAAACCATC 516 303 1653 Antisense
AATCGCACTGAATCTCGTGGAGCCC 625 167 1690 Antisense
AGCCCACGCTCGTGATGATTTCCAA 110 83 1710 Antisense
AAACCGTTTGATCAGCACTGGCGCA 115 127 1786 Antisense
GCAAGCATTCCATCATCGGTATCGA 597 319 1808 Antisense
GAGCTGTTGATTTGACATACCGCCC 301 387 1844 Antisense
Sequence Source Affymetrix Proprietary Database